Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   DQM66_RS01870 Genome accession   NZ_LS483374
Coordinates   349155..349844 (+) Length   229 a.a.
NCBI ID   WP_000518011.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain NCTC7466     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 344155..354844
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM66_RS01845 (NCTC7466_00348) gpsB 344264..344593 (+) 330 WP_000146522.1 cell division regulator GpsB -
  DQM66_RS01855 (NCTC7466_00350) - 345079..346236 (+) 1158 WP_000711391.1 THUMP domain-containing class I SAM-dependent RNA methyltransferase -
  DQM66_RS01860 (NCTC7466_00351) mapZ 346249..347643 (+) 1395 WP_000039255.1 cell division site-positioning protein MapZ -
  DQM66_RS01865 (NCTC7466_00352) gndA 347719..349143 (+) 1425 WP_000158781.1 NADP-dependent phosphogluconate dehydrogenase -
  DQM66_RS01870 (NCTC7466_00353) covR 349155..349844 (+) 690 WP_000518011.1 response regulator transcription factor Regulator
  DQM66_RS01875 (NCTC7466_00354) cbpC 349942..350958 (+) 1017 WP_000771103.1 choline-binding protein CbpC -
  DQM66_RS01880 (NCTC7466_00355) mvk 351080..351958 (+) 879 WP_000163321.1 mevalonate kinase -
  DQM66_RS01885 (NCTC7466_00356) mvaD 351940..352893 (+) 954 WP_000373458.1 diphosphomevalonate decarboxylase -
  DQM66_RS01890 (NCTC7466_00357) - 352880..353887 (+) 1008 WP_000562411.1 phosphomevalonate kinase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26880.19 Da        Isoelectric Point: 6.9836

>NTDB_id=1139029 DQM66_RS01870 WP_000518011.1 349155..349844(+) (covR) [Streptococcus pneumoniae strain NCTC7466]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1139029 DQM66_RS01870 WP_000518011.1 349155..349844(+) (covR) [Streptococcus pneumoniae strain NCTC7466]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGCCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACACGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGACAAA
AAAGCTACATTAAAACTGTGCGTGGTGTTGGATATACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467

Multiple sequence alignment