Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilA   Type   Machinery gene
Locus tag   DQM57_RS08380 Genome accession   NZ_LS483369
Coordinates   1621628..1623052 (+) Length   474 a.a.
NCBI ID   WP_111727510.1    Uniprot ID   A0A7T3BLV7
Organism   Neisseria cinerea strain NCTC10294     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1616628..1628052
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM57_RS08355 (NCTC10294_01590) - 1617275..1617547 (-) 273 WP_111727505.1 membrane lipoprotein lipid attachment site-containing protein -
  DQM57_RS08360 (NCTC10294_01591) - 1617573..1618253 (-) 681 WP_111727506.1 pyrimidine 5'-nucleotidase -
  DQM57_RS08365 (NCTC10294_01592) - 1618312..1619313 (+) 1002 WP_111727507.1 thiamine ABC transporter substrate-binding protein -
  DQM57_RS08370 (NCTC10294_01593) - 1619344..1619829 (+) 486 WP_111727508.1 CinA family protein -
  DQM57_RS08375 (NCTC10294_01594) msrAB 1619914..1621482 (-) 1569 WP_111727509.1 bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB -
  DQM57_RS08380 (NCTC10294_01595) pilA 1621628..1623052 (+) 1425 WP_111727510.1 signal recognition particle-docking protein FtsY Machinery gene
  DQM57_RS08385 (NCTC10294_01596) - 1623363..1623629 (+) 267 WP_019271767.1 DUF3079 domain-containing protein -
  DQM57_RS08390 (NCTC10294_01597) - 1623839..1624099 (+) 261 WP_111727511.1 hypothetical protein -
  DQM57_RS08395 (NCTC10294_01598) pilA2 1624167..1624643 (+) 477 WP_108044216.1 pilin Machinery gene
  DQM57_RS09980 (NCTC10294_01599) - 1624684..1625307 (+) 624 WP_269460473.1 pilin -
  DQM57_RS09985 - 1625304..1625426 (-) 123 WP_003678392.1 hypothetical protein -
  DQM57_RS08405 (NCTC10294_01600) yccS 1625446..1627596 (-) 2151 WP_111727512.1 YccS family putative transporter -

Sequence

Protein


Download         Length: 474 a.a.        Molecular weight: 50906.56 Da        Isoelectric Point: 4.3031

>NTDB_id=1138964 DQM57_RS08380 WP_111727510.1 1621628..1623052(+) (pilA) [Neisseria cinerea strain NCTC10294]
MFSFFRRKKKQETPAPEEAQVQETAAKIESEVAQVIENIKEDSESLAESVKGNVESVVESAVETVSETVSETVEQVREAL
TETLSETVEKVEEHVEAAKEAAVETASEALEQVKETVAEMPSEVAEAAEEAVEQAEAVKEEAVEAVSEAVEPVQEAVAET
PAEASAPAEEHKLSWAARLKQGLTKSRDKMAKSLAGVFGGGQIDEDLYEELETVLITSDMGMEATEYLMKDVRDRVSLKG
LKDGNELRGALKDALYDLIKPLEKPLVLPETKEPFVIMLAGINGAGKTTSIGKLAKYFQAQGKSVLLAAGDTFRAAAREQ
LQAWGERNNVTVISQTTGDSAAVCFDAVQAAKARGIDIVLADTAGRLPTQLHLMEEIKKVKRVLQKAMPDAPHEIIVVLD
ANIGQNAVNQVKAFDDALGLTGLIVTKLDGTAKGGILAALASDRPVPVRYIGVGEGIDDLRPFDARAFVDALLD

Nucleotide


Download         Length: 1425 bp        

>NTDB_id=1138964 DQM57_RS08380 WP_111727510.1 1621628..1623052(+) (pilA) [Neisseria cinerea strain NCTC10294]
ATGTTCAGCTTCTTCCGTCGCAAGAAAAAACAGGAAACTCCGGCTCCTGAGGAGGCTCAAGTTCAGGAAACCGCAGCAAA
AATAGAATCTGAAGTTGCTCAAGTAATTGAAAATATTAAAGAAGATTCCGAATCTTTAGCAGAAAGCGTCAAAGGGAATG
TTGAATCAGTTGTCGAATCGGCTGTTGAAACTGTCAGCGAAACCGTCAGCGAAACCGTCGAGCAGGTTCGGGAAGCTTTG
ACCGAAACGCTGTCTGAAACAGTCGAAAAAGTAGAAGAACACGTTGAAGCGGCAAAAGAAGCGGCTGTTGAAACCGCCAG
CGAGGCTCTTGAACAGGTAAAAGAAACCGTTGCCGAGATGCCGTCTGAAGTGGCTGAAGCTGCTGAGGAAGCAGTAGAAC
AGGCCGAAGCAGTCAAAGAAGAAGCTGTTGAGGCAGTTAGCGAAGCTGTCGAGCCAGTTCAAGAAGCCGTTGCGGAAACA
CCGGCTGAAGCCTCTGCTCCGGCAGAAGAACATAAGCTCAGTTGGGCGGCGCGTTTGAAACAAGGCTTGACCAAATCACG
CGACAAAATGGCAAAATCGCTGGCGGGCGTGTTCGGCGGCGGACAGATCGACGAGGATTTGTACGAAGAGCTGGAAACCG
TGTTGATTACCAGCGACATGGGCATGGAAGCGACGGAATACCTGATGAAAGACGTGCGCGACCGCGTCAGCCTCAAAGGG
CTGAAAGACGGCAACGAATTGCGCGGCGCGCTGAAGGATGCGCTGTACGACCTGATTAAGCCGTTGGAAAAACCGCTGGT
CTTGCCCGAAACCAAAGAGCCTTTCGTGATTATGCTTGCCGGTATCAACGGCGCGGGCAAAACCACGTCTATCGGCAAAC
TCGCCAAATATTTCCAAGCGCAGGGCAAATCCGTATTGCTGGCGGCAGGCGATACTTTCCGCGCAGCCGCGCGTGAGCAG
CTTCAGGCTTGGGGAGAGCGCAACAACGTAACCGTGATTTCGCAAACCACGGGCGATTCCGCAGCCGTTTGTTTTGATGC
CGTCCAAGCCGCCAAAGCGCGCGGCATCGACATCGTGCTGGCCGACACCGCCGGCCGCCTGCCCACGCAGCTTCATTTGA
TGGAAGAAATCAAAAAAGTGAAGCGCGTACTGCAAAAAGCCATGCCCGACGCGCCGCACGAAATCATCGTCGTGCTTGAT
GCCAACATCGGGCAAAACGCCGTCAACCAAGTCAAAGCCTTTGACGACGCATTGGGGCTGACCGGTTTAATCGTTACCAA
GCTAGACGGCACGGCAAAAGGCGGCATCCTTGCCGCGCTTGCCTCCGACCGCCCAGTTCCTGTCCGCTACATCGGCGTAG
GCGAAGGCATAGACGATTTGCGTCCGTTTGACGCGCGCGCGTTTGTGGACGCACTGCTGGATTGA

Domains

Predicted by InterproScan.

SRP54-type protein, helical bundle domain (SRP54_N)

(189-255)

SRP54-type protein, GTPase domain (SRP54)

(274-473)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7T3BLV7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilA Neisseria gonorrhoeae MS11

79.536

100

0.795

Multiple sequence alignment