Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   DQM60_RS07235 Genome accession   NZ_LS483366
Coordinates   1570493..1571719 (-) Length   408 a.a.
NCBI ID   WP_002890340.1    Uniprot ID   J7SIE0
Organism   Streptococcus salivarius strain NCTC7366     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1565493..1576719
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM60_RS07205 (NCTC7366_01450) plsY 1565838..1566479 (+) 642 WP_014633423.1 glycerol-3-phosphate 1-O-acyltransferase PlsY -
  DQM60_RS07210 (NCTC7366_01451) - 1566597..1566974 (-) 378 WP_002885939.1 helix-hairpin-helix domain-containing protein -
  DQM60_RS07215 (NCTC7366_01452) - 1567049..1567303 (-) 255 WP_002886199.1 DUF1912 family protein -
  DQM60_RS07220 (NCTC7366_01453) mmuM 1567416..1568366 (-) 951 WP_049553995.1 homocysteine S-methyltransferase -
  DQM60_RS07225 (NCTC7366_01454) - 1568378..1569754 (-) 1377 WP_049553996.1 amino acid permease -
  DQM60_RS07230 (NCTC7366_01455) yihA 1569884..1570483 (-) 600 WP_002885996.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  DQM60_RS07235 (NCTC7366_01456) clpX 1570493..1571719 (-) 1227 WP_002890340.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  DQM60_RS07240 (NCTC7366_01457) - 1571737..1571907 (-) 171 WP_002886174.1 hypothetical protein -
  DQM60_RS07245 (NCTC7366_01458) - 1571912..1572415 (-) 504 WP_045001870.1 dihydrofolate reductase -
  DQM60_RS07250 (NCTC7366_01459) - 1572524..1573384 (-) 861 WP_014633426.1 thymidylate synthase -
  DQM60_RS07255 (NCTC7366_01460) - 1573690..1574856 (+) 1167 WP_014633427.1 hydroxymethylglutaryl-CoA synthase -
  DQM60_RS07260 (NCTC7366_01461) - 1574858..1576129 (+) 1272 WP_084871476.1 hydroxymethylglutaryl-CoA reductase, degradative -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 44993.33 Da        Isoelectric Point: 4.3489

>NTDB_id=1138788 DQM60_RS07235 WP_002890340.1 1570493..1571719(-) (clpX) [Streptococcus salivarius strain NCTC7366]
MAGNRNEEMVYCSFCGKNQEEVKKIIAGNGVFICNECVALSQEIIREEMAEEVLADLAETPKPKELLDILNNYVVGQDRA
KRALAVAVYNHYKRINFTESREDNDVDLQKSNILMIGPTGSGKTFLAQTLARSLNVPFAIADATSLTEAGYVGEDVENIL
LKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKN
ILFIVGGAFDGIEDIVKQRLGEKIIGFGQNNKAIDDDSSYMQEIVAEDIQKFGLIPEFIGRLPVLAALEQLTVDDLVRIL
TEPRNALVKQYQTLLSYDGVELEFDQDALEAIASKAIERKTGARGLRSIIEEVMMDVMFEIPSQEDVTKVRITKEAVDGT
AAPVLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=1138788 DQM60_RS07235 WP_002890340.1 1570493..1571719(-) (clpX) [Streptococcus salivarius strain NCTC7366]
ATGGCTGGAAATCGTAATGAAGAAATGGTTTATTGTTCATTTTGTGGCAAAAACCAAGAAGAAGTAAAGAAAATTATTGC
CGGCAATGGCGTCTTTATCTGTAACGAATGTGTGGCCTTGTCACAAGAAATCATTCGTGAGGAAATGGCAGAAGAAGTTT
TGGCTGACTTGGCTGAAACACCAAAGCCAAAAGAACTTTTGGATATTTTGAACAATTATGTCGTGGGGCAAGACCGTGCT
AAACGTGCCTTGGCGGTAGCTGTTTACAACCACTATAAACGTATCAACTTCACAGAAAGTCGTGAAGACAATGATGTTGA
TTTGCAAAAATCAAATATTCTCATGATTGGACCAACTGGTTCAGGGAAGACTTTCTTGGCTCAGACCTTGGCTCGTAGCT
TGAATGTTCCTTTCGCGATTGCGGATGCGACATCATTGACTGAGGCAGGTTATGTGGGTGAGGACGTGGAAAATATCCTC
CTCAAACTGATCCAAGCGGCAGACTTCAATATTGAACGTGCGGAACGTGGCATCATCTATGTCGACGAGATTGATAAGAT
TGCTAAAAAAGGTGAAAACGTATCAATCACTCGTGACGTTTCTGGTGAAGGGGTTCAACAAGCCCTCTTGAAGATTATCG
AAGGAACAGTAGCTAGCGTTCCACCTCAAGGTGGCCGTAAACACCCTAACCAAGAGATGATTCAAATTGATACAAAGAAT
ATTCTTTTTATCGTAGGTGGTGCTTTTGATGGTATCGAAGATATCGTTAAGCAACGTCTTGGTGAGAAAATCATTGGTTT
TGGTCAAAATAATAAGGCTATTGATGATGACTCATCATACATGCAAGAAATTGTGGCTGAAGATATCCAAAAATTCGGTC
TTATCCCCGAGTTTATCGGACGTTTGCCAGTCCTTGCGGCCCTTGAACAGTTAACGGTGGATGACTTGGTTCGTATCTTG
ACAGAGCCTAGAAATGCCTTGGTTAAACAGTATCAAACCCTCTTGTCTTATGATGGGGTTGAACTTGAGTTTGACCAGGA
TGCTCTTGAAGCTATTGCAAGTAAGGCGATTGAACGTAAGACTGGTGCGCGTGGGCTTCGCTCTATCATTGAAGAAGTCA
TGATGGATGTCATGTTTGAAATTCCTAGCCAGGAAGATGTGACTAAGGTTCGTATTACTAAAGAAGCCGTTGACGGTACA
GCTGCTCCAGTTTTGGAAACAGCGTAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB J7SIE0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

89.976

100

0.902
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.606

98.284

0.566

Multiple sequence alignment