Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   SFR_RS26295 Genome accession   NZ_CP009802
Coordinates   5939883..5940551 (+) Length   222 a.a.
NCBI ID   WP_003947363.1    Uniprot ID   A0ABR4S4B0
Organism   Streptomyces sp. FR-008     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 5934883..5945551
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SFR_RS26275 (SFR_5871) - 5935449..5936171 (-) 723 WP_008403843.1 transglycosylase SLT domain-containing protein -
  SFR_RS26280 (SFR_5873) - 5936628..5937725 (-) 1098 WP_075987486.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
  SFR_RS26285 (SFR_5872) - 5937722..5938441 (-) 720 WP_018470478.1 SDR family oxidoreductase -
  SFR_RS26290 (SFR_5875) - 5938715..5939890 (+) 1176 WP_075987487.1 GAF domain-containing sensor histidine kinase -
  SFR_RS26295 (SFR_5876) vraR 5939883..5940551 (+) 669 WP_003947363.1 response regulator transcription factor Regulator
  SFR_RS26300 (SFR_5878) - 5940730..5940975 (+) 246 WP_075987488.1 chaplin family protein -
  SFR_RS26305 (SFR_5879) - 5941053..5941826 (-) 774 WP_067411139.1 hypothetical protein -
  SFR_RS26310 (SFR_5880) - 5941957..5942754 (+) 798 WP_015508085.1 ABC transporter ATP-binding protein -
  SFR_RS26315 - 5942821..5943249 (+) 429 WP_003947359.1 NfeD family protein -
  SFR_RS26320 - 5943366..5944313 (+) 948 WP_008410203.1 SPFH domain-containing protein -
  SFR_RS26325 (SFR_5882) - 5944387..5944893 (-) 507 WP_003947357.1 HNH endonuclease -

Sequence

Protein


Download         Length: 222 a.a.        Molecular weight: 24298.67 Da        Isoelectric Point: 5.9095

>NTDB_id=113869 SFR_RS26295 WP_003947363.1 5939883..5940551(+) (vraR) [Streptomyces sp. FR-008]
MADTEREERHTQVIRVLLVDDHQVVRRGLRTFLEVQDDIEVVGEAGDGAEGVARAEELQPDVVLMDVKMPGMDGVEALRR
LRELANPARVLVVTSFTEQRTVVPALRAGAGGYVYKDVDPEALARAIRSVHAGHVLLQPEVAGALLSQDEHGQGQGRGGS
LTEREREVLGLIADGRSNREIARALVLSEKTVKTHVSNILMKLDLADRTQAALWAVRHGMAR

Nucleotide


Download         Length: 669 bp        

>NTDB_id=113869 SFR_RS26295 WP_003947363.1 5939883..5940551(+) (vraR) [Streptomyces sp. FR-008]
GTGGCTGACACCGAGCGCGAGGAACGGCACACCCAGGTCATCCGGGTCCTCCTCGTCGACGACCACCAGGTGGTCCGCCG
CGGCCTGCGCACCTTCCTGGAGGTCCAGGACGACATCGAGGTGGTCGGCGAGGCCGGCGACGGAGCCGAAGGCGTGGCCC
GCGCCGAGGAGCTCCAGCCCGACGTCGTCCTGATGGACGTCAAGATGCCCGGCATGGACGGCGTCGAGGCCCTGCGCCGC
CTGCGGGAACTGGCCAACCCCGCCCGCGTCCTGGTCGTCACCAGCTTCACCGAGCAGCGCACCGTGGTCCCCGCCCTGCG
CGCCGGCGCCGGGGGATACGTCTACAAGGACGTCGACCCCGAGGCGCTGGCCCGCGCCATCCGCTCCGTCCACGCCGGCC
ACGTCCTCCTCCAGCCCGAGGTCGCCGGCGCCCTCCTCAGCCAGGACGAGCACGGCCAGGGCCAGGGGCGCGGCGGCTCC
CTGACCGAACGCGAACGCGAGGTGCTCGGCCTGATCGCCGACGGCCGCTCCAACCGCGAGATCGCCCGCGCCCTCGTCCT
CTCCGAGAAGACGGTGAAGACCCACGTCTCGAACATCCTGATGAAACTCGACCTCGCCGACCGCACCCAGGCCGCCCTGT
GGGCCGTACGCCACGGAATGGCACGCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(160-215)

Response regulator receiver domain (Response_reg)

(16-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

45.411

93.243

0.423
  degU Bacillus subtilis subsp. subtilis str. 168

38.009

99.55

0.378