Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   DQM55_RS02825 Genome accession   NZ_LS483364
Coordinates   549488..550786 (+) Length   432 a.a.
NCBI ID   WP_002920044.1    Uniprot ID   A0A2X4AK83
Organism   Streptococcus sanguinis strain NCTC11086     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 544488..555786
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM55_RS02800 (NCTC11086_00556) - 545229..545861 (+) 633 WP_111675396.1 response regulator transcription factor -
  DQM55_RS02805 (NCTC11086_00557) - 545901..547301 (+) 1401 WP_111675397.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  DQM55_RS02810 (NCTC11086_00558) - 547301..547663 (+) 363 WP_111675398.1 S1 RNA-binding domain-containing protein -
  DQM55_RS02815 (NCTC11086_00559) cysK 547770..548699 (-) 930 WP_004185656.1 cysteine synthase A -
  DQM55_RS02820 (NCTC11086_00560) - 548800..549432 (-) 633 WP_111675399.1 YigZ family protein -
  DQM55_RS02825 (NCTC11086_00561) comFA/cflA 549488..550786 (+) 1299 WP_002920044.1 DEAD/DEAH box helicase Machinery gene
  DQM55_RS02830 (NCTC11086_00562) - 550783..551448 (+) 666 WP_111675400.1 ComF family protein -
  DQM55_RS02835 (NCTC11086_00563) hpf 551530..552072 (+) 543 WP_002893481.1 ribosome hibernation-promoting factor, HPF/YfiA family -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49470.27 Da        Isoelectric Point: 8.6271

>NTDB_id=1138661 DQM55_RS02825 WP_002920044.1 549488..550786(+) (comFA/cflA) [Streptococcus sanguinis strain NCTC11086]
MLELQDCLGRIFTESQLESSLRAQAKEIPSIREEKGKLHCGRCNSLIERENQLPVGAYYCRECLILGRVRSDQKLYYFPQ
EDFPKKQVLKWQGQLTEFQGKVSKGLLDALEKRQNTLVHAVTGAGKTEMIYQVIARVIDRGGSVCLASPRIDVCLELYRR
LKEDFSCEIALLHGESEAYFRSPLVIATTHQLLKFYRAFDLLIVDEVDAFPYVDNPILYHAVERSVKEDATTIFLTATST
DELDKRVQKGELKRLSLPRRFHGNPLTIPQKVWLSDFQKHLQKKKIAPKLLKYIQKQRETQFPLLIFAAEIQRGEDVAQA
LQIALPDEKLAFVASTTENRLEIVEQFRRKEITILVTTTILERGVTFPGVDVFVLEANHRLFSRSALVQISGRVGRSMDR
PTGQLLFFHDGTTLAMEKAIREMRDMNKEAGL

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=1138661 DQM55_RS02825 WP_002920044.1 549488..550786(+) (comFA/cflA) [Streptococcus sanguinis strain NCTC11086]
ATGTTAGAGTTGCAAGATTGTTTAGGACGTATATTTACAGAGAGTCAGTTAGAGTCTAGCTTGCGAGCACAAGCAAAAGA
AATTCCCAGTATCCGAGAAGAAAAAGGCAAGCTCCACTGCGGACGCTGCAACAGCTTGATTGAACGAGAAAATCAGCTAC
CTGTTGGAGCTTATTATTGTAGAGAATGCTTAATATTGGGCCGGGTACGGAGTGACCAAAAACTTTACTATTTTCCTCAA
GAGGATTTTCCTAAAAAACAGGTGCTTAAATGGCAGGGGCAACTGACAGAGTTTCAGGGGAAGGTCTCCAAAGGCTTACT
GGATGCGCTAGAGAAAAGACAGAATACGTTAGTGCATGCTGTTACTGGCGCTGGAAAAACAGAAATGATTTACCAAGTGA
TTGCAAGAGTTATTGATAGAGGAGGGTCTGTTTGCTTGGCCAGTCCGCGGATTGATGTTTGTTTAGAACTTTATCGGCGC
CTAAAAGAAGACTTTTCTTGTGAAATAGCCCTTCTGCATGGGGAGTCAGAAGCTTATTTTCGCAGCCCCTTGGTAATTGC
GACCACCCACCAGCTCTTAAAATTTTATCGGGCTTTTGATTTGTTGATTGTGGACGAGGTAGACGCCTTTCCTTATGTGG
ATAATCCCATACTGTATCACGCTGTAGAGCGTTCAGTTAAAGAGGATGCTACAACTATTTTTCTGACAGCCACTTCCACA
GATGAATTGGATAAAAGAGTTCAAAAAGGTGAGTTGAAACGCCTGAGTCTTCCCAGAAGATTTCATGGTAATCCCTTGAC
CATCCCTCAGAAAGTTTGGTTATCTGATTTTCAAAAACATCTTCAGAAGAAGAAAATAGCACCTAAACTTTTAAAATATA
TACAAAAACAGAGGGAGACTCAATTTCCTCTCTTAATATTTGCTGCAGAAATTCAAAGAGGAGAGGATGTTGCTCAGGCT
TTGCAGATAGCTCTGCCTGATGAAAAGCTGGCTTTTGTCGCCTCTACAACAGAAAATCGTCTAGAGATTGTCGAGCAGTT
TCGTCGCAAGGAGATCACTATTTTGGTGACAACGACTATCTTAGAGCGTGGAGTAACTTTTCCTGGCGTGGATGTTTTTG
TCTTGGAAGCCAATCATCGCTTGTTCAGTCGTAGTGCTCTGGTTCAGATTTCAGGCCGAGTTGGCCGTAGTATGGATAGA
CCGACTGGACAGTTGCTATTTTTTCATGATGGGACTACCCTTGCTATGGAAAAAGCAATTCGAGAAATGAGAGATATGAA
TAAGGAGGCGGGATTATGA

Domains

Predicted by InterproScan.

DEAD/DEAH box helicase (DEAD)

(109-244)

Helicase conserved C-terminal domain (Helicase_C)

(290-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2X4AK83

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

70.726

98.843

0.699
  comFA/cflA Streptococcus pneumoniae D39

70.726

98.843

0.699
  comFA/cflA Streptococcus pneumoniae R6

70.726

98.843

0.699
  comFA/cflA Streptococcus pneumoniae TIGR4

70.492

98.843

0.697
  comFA/cflA Streptococcus mitis NCTC 12261

70.588

98.38

0.694
  comFA/cflA Streptococcus mitis SK321

69.412

98.38

0.683
  comFA Lactococcus lactis subsp. cremoris KW2

55.025

92.13

0.507
  comFA Latilactobacillus sakei subsp. sakei 23K

38.889

100

0.389

Multiple sequence alignment