Detailed information NTG1138275

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: DQM51_RS03875
• Genome accession: NZ_LS483356
• Coordinates: 727693..728922 (+)
• Length: 409 a.a.
• NCBI ID: WP_111713211.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC8230
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 722693..733922

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM51_RS03850 (NCTC8230_00765)	-	723309..724586 (-)	1278	WP_111713209.1	hydroxymethylglutaryl-CoA reductase, degradative	-
DQM51_RS03855 (NCTC8230_00766)	-	724573..725748 (-)	1176	WP_021299369.1	hydroxymethylglutaryl-CoA synthase	-
DQM51_RS03860 (NCTC8230_00767)	-	725957..726796 (+)	840	WP_010922172.1	thymidylate synthase	-
DQM51_RS03865 (NCTC8230_00768)	-	726876..727373 (+)	498	WP_111713210.1	dihydrofolate reductase	-
DQM51_RS03870 (NCTC8230_00769)	-	727393..727563 (+)	171	WP_002984950.1	hypothetical protein	-
DQM51_RS03875 (NCTC8230_00770)	clpX	727693..728922 (+)	1230	WP_111713211.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
DQM51_RS03880 (NCTC8230_00771)	yihA	728932..729531 (+)	600	WP_002984945.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
DQM51_RS03885 (NCTC8230_00772)	-	729679..730422 (+)	744	WP_002984942.1	hypothetical protein	-
DQM51_RS03890 (NCTC8230_00773)	-	730480..732579 (-)	2100	WP_002984939.1	AAA family ATPase	-
DQM51_RS03895 (NCTC8230_00774)	rpiA	732957..733640 (+)	684	WP_002984936.1	ribose-5-phosphate isomerase RpiA	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 44992.42 Da
• Isoelectric Point: 4.5458

>NTDB_id=1138275 DQM51_RS03875 WP_111713211.1 727693..728922(+) (clpX) [Streptococcus pyogenes strain NCTC8230]
MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDR
AKRALSVAVYNHYKRVSFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
DILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIQI
LTEPRNALVKQYQALLSYDGVELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEG
KSKPVLETA

Nucleotide

• Length: 1230 bp

>NTDB_id=1138275 DQM51_RS03875 WP_111713211.1 727693..728922(+) (clpX) [Streptococcus pyogenes strain NCTC8230]
ATGGCAGGAAGTAGAACTAACGATATTAAAGTATACTGTTCATTTTGTGGTAAAAGCCAGGATGACGTTAAAAAAATTAT
CGCAGGAAATAATGTTTTCATCTGCAATGAATGCGTAGCTTTATCACAAGAAATTATAAAAGAAGAATTGGCTGAAGAAG
TCCTTGCCGATTTGACAGAAGTTCCAAAACCAAAAGAGCTCCTTGATGTTTTAAATCAATATGTGGTTGGTCAAGATCGT
GCTAAACGTGCTTTATCAGTTGCTGTGTACAATCATTATAAGCGTGTCTCGTTTACAGAAAGTCGTGATGACGATGATGT
GGATTTACAAAAGTCCAACATTTTGATGATTGGACCAACAGGTTCAGGAAAAACCTTCTTAGCACAAACTCTGGCTAAAA
GCCTCAATGTACCATTTGCTATTGCAGATGCAACTTCTTTGACTGAAGCAGGGTATGTTGGAGAAGATGTGGAAAATATT
TTACTCAAACTGATTCAGGCTGCTGACTATAATGTCGAACGAGCAGAGCGTGGTATTATTTATGTTGATGAAATAGATAA
GATTGCTAAAAAAGGTGAGAACGTATCTATCACACGTGATGTATCTGGTGAAGGTGTACAGCAAGCCCTTCTTAAAATTA
TTGAAGGTACGGTAGCAAGTGTTCCCCCACAAGGTGGGCGGAAGCACCCTAATCAAGAAATGATCCAAATTGATACAAAA
GATATCTTGTTTATTGTTGGCGGGGCTTTTGATGGCATCGAGGAGATTGTTAAACAACGTTTAGGTGAAAAAGTTATTGG
TTTTGGTCAAAACAGCCGTAAAATTGATGACAATGCTTCTTATATGCAAGAAATTATTTCAGAAGATATTCAAAAGTTTG
GGCTTATTCCAGAATTTATTGGCCGCTTACCAGTTGTGGCAGCCCTTGAACAACTAAACACATCAGATTTGATTCAAATT
TTGACAGAACCAAGAAATGCCCTGGTCAAGCAATATCAGGCTCTTCTTTCTTACGATGGCGTCGAATTGGCATTTGATAA
GGAAGCCTTAGAAGCCATTGCCAATAAAGCCATTGAACGTAAGACAGGAGCACGTGGTCTTCGTTCTATTATCGAAGAAA
CGATGTTAGACATTATGTTTGAAATTCCAAGCCAAGAAGATGTCACAAAAGTGCGTATCACCAAGGCTGCTGTCGAAGGC
AAGTCAAAACCCGTTTTAGAGACAGCTTAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-391)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	88.753	100	0.888
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.354	98.044	0.572