Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   DQM59_RS08040 Genome accession   NZ_LS483349
Coordinates   1584792..1586093 (-) Length   433 a.a.
NCBI ID   WP_002279927.1    Uniprot ID   -
Organism   Streptococcus mutans strain NCTC10449     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1579792..1591093
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM59_RS08015 (NCTC10449_01558) - 1579850..1580485 (+) 636 WP_002263021.1 hypothetical protein -
  DQM59_RS08020 (NCTC10449_01559) - 1580565..1582265 (-) 1701 WP_002263022.1 zinc ribbon domain-containing protein -
  DQM59_RS08025 (NCTC10449_01560) - 1582285..1583379 (-) 1095 WP_002266342.1 hypothetical protein -
  DQM59_RS08030 (NCTC10449_01561) hpf 1583503..1584051 (-) 549 WP_002263024.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  DQM59_RS08035 (NCTC10449_01562) - 1584130..1584795 (-) 666 WP_002270131.1 ComF family protein -
  DQM59_RS08040 (NCTC10449_01563) comFA/cflA 1584792..1586093 (-) 1302 WP_002279927.1 DEAD/DEAH box helicase Machinery gene
  DQM59_RS08045 (NCTC10449_01564) - 1586166..1586795 (+) 630 WP_002263027.1 YigZ family protein -
  DQM59_RS08050 (NCTC10449_01565) cysK 1586886..1587812 (+) 927 WP_002279926.1 cysteine synthase A -
  DQM59_RS08055 (NCTC10449_01566) - 1588146..1589237 (-) 1092 WP_002263029.1 glycerol dehydrogenase -
  DQM59_RS08060 (NCTC10449_01567) - 1589275..1589943 (-) 669 WP_002279925.1 fructose-6-phosphate aldolase -

Sequence

Protein


Download         Length: 433 a.a.        Molecular weight: 49481.72 Da        Isoelectric Point: 9.9950

>NTDB_id=1137901 DQM59_RS08040 WP_002279927.1 1584792..1586093(-) (comFA/cflA) [Streptococcus mutans strain NCTC10449]
MENLENYYGRLLTENQMNSDLKKQAKILPAMIKKPHYFICNRCGSQNNLGNALPDGSIYCRACLVFGRLTNRDSLYYFEQ
KPFPKGQVLRWQGQLTPFQQEVSRGLKKSVCHKENMLIHAVTGAGKTEMIYETLASILNQGGAVALASPRIDVCIELYKR
LSRDFSCPISLLYGESEAYERSPLVIATTHQLLKFYRAFDLLIIDEVDAFPFVDNKMLYYAVDHCLKSDGVKVFLTATST
DQLDKQVKQGKLKKLHLARRFHANPLVVPKPIWLNLSLERLQRGKLPRSFLQQIRIQRQIQFPLLIFFPNIEDGLTFAKS
LQTYLPNEKIDFVSSLTTDRLEKVENFRKGNTQILVSTTILERGVTFPCVDVFVMMSNHYLFTKSSLVQIAGRVGRSADR
PDGKLLFFHNGMNRAMKKAIMEIKTMNKKGGFA

Nucleotide


Download         Length: 1302 bp        

>NTDB_id=1137901 DQM59_RS08040 WP_002279927.1 1584792..1586093(-) (comFA/cflA) [Streptococcus mutans strain NCTC10449]
ATGGAGAATTTAGAGAATTATTATGGCCGCCTCTTGACCGAGAATCAAATGAACAGTGATTTGAAAAAGCAAGCTAAAAT
CTTGCCAGCTATGATAAAAAAACCGCATTACTTTATCTGCAATCGTTGCGGCAGTCAGAACAATCTTGGTAATGCTTTGC
CGGATGGATCTATCTACTGTCGAGCTTGTCTTGTCTTTGGACGTCTTACTAACAGGGACAGTCTTTATTATTTTGAGCAA
AAGCCTTTTCCAAAGGGTCAGGTCTTAAGGTGGCAAGGGCAATTAACCCCTTTTCAGCAGGAAGTTTCCCGTGGTTTAAA
AAAGAGTGTTTGCCATAAGGAAAATATGCTTATTCATGCTGTAACAGGTGCAGGCAAAACGGAGATGATTTATGAAACTC
TGGCCAGCATTCTCAATCAAGGGGGTGCGGTTGCACTTGCTAGTCCTCGCATTGATGTCTGCATAGAACTGTATAAACGT
TTAAGTCGTGACTTTTCTTGTCCTATCAGTCTTTTGTATGGAGAGTCAGAAGCTTATGAACGCAGTCCATTAGTGATTGC
AACCACGCATCAACTTTTGAAATTTTACCGAGCTTTTGATTTGTTAATTATTGATGAAGTAGATGCCTTTCCTTTTGTTG
ACAATAAGATGCTCTATTATGCTGTAGATCATTGTCTGAAATCAGATGGTGTCAAAGTATTTTTGACTGCAACTTCGACT
GACCAATTAGACAAACAGGTTAAGCAAGGGAAGCTAAAAAAACTGCATTTAGCCAGACGATTTCATGCCAATCCCTTAGT
TGTTCCCAAGCCAATTTGGTTGAATTTATCTCTTGAAAGATTACAAAGAGGTAAATTACCGCGCTCTTTTTTACAGCAGA
TAAGAATTCAAAGGCAGATTCAATTCCCTCTTTTGATCTTTTTTCCGAATATTGAAGATGGTTTAACCTTTGCTAAATCA
CTGCAAACCTATCTTCCAAATGAGAAAATTGATTTTGTTTCCAGCTTGACAACAGATCGTTTAGAAAAAGTCGAAAATTT
TAGAAAAGGAAACACACAAATTTTGGTTTCAACAACGATTTTAGAGAGGGGAGTCACTTTTCCTTGTGTAGATGTTTTTG
TCATGATGAGCAACCATTATCTGTTCACCAAAAGTTCTCTGGTACAGATTGCTGGTCGTGTGGGACGCTCTGCCGATAGA
CCAGATGGAAAATTACTTTTCTTTCATAATGGAATGAACAGAGCCATGAAAAAGGCCATTATGGAAATCAAGACTATGAA
CAAAAAAGGAGGTTTTGCATGA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(94-168)

Helicase conserved C-terminal domain (Helicase_C)

(296-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

59.251

98.614

0.584
  comFA/cflA Streptococcus pneumoniae D39

59.251

98.614

0.584
  comFA/cflA Streptococcus pneumoniae R6

59.251

98.614

0.584
  comFA/cflA Streptococcus pneumoniae TIGR4

59.251

98.614

0.584
  comFA/cflA Streptococcus mitis NCTC 12261

58.548

98.614

0.577
  comFA/cflA Streptococcus mitis SK321

58.548

98.614

0.577
  comFA Lactococcus lactis subsp. cremoris KW2

51.777

90.993

0.471
  comFA Latilactobacillus sakei subsp. sakei 23K

38.695

99.076

0.383

Multiple sequence alignment