Detailed information NTG1137826

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: DQM48_RS06000
• Genome accession: NZ_LS483348
• Coordinates: 1150855..1152084 (-)
• Length: 409 a.a.
• NCBI ID: WP_020916897.1
• Uniprot ID: A0AB33AMD1
• Organism: Streptococcus lutetiensis strain NCTC8738
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1145855..1157084

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM48_RS05980 (NCTC8738_01245)	-	1147084..1147752 (+)	669	WP_043895254.1	YoaK family protein	-
DQM48_RS05985 (NCTC8738_01246)	mmuM	1147784..1148728 (-)	945	Protein_1115	homocysteine S-methyltransferase	-
DQM48_RS05990 (NCTC8738_01248)	-	1148747..1150038 (-)	1292	Protein_1116	amino acid permease	-
DQM48_RS05995 (NCTC8738_01249)	yihA	1150251..1150844 (-)	594	WP_043895055.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
DQM48_RS06000 (NCTC8738_01250)	clpX	1150855..1152084 (-)	1230	WP_020916897.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
DQM48_RS06010 (NCTC8738_01252)	-	1152311..1152805 (-)	495	WP_111698831.1	dihydrofolate reductase	-
DQM48_RS06015 (NCTC8738_01253)	-	1152888..1153727 (-)	840	WP_111698833.1	thymidylate synthase	-
DQM48_RS06020 (NCTC8738_01254)	-	1154055..1155230 (+)	1176	WP_111698835.1	hydroxymethylglutaryl-CoA synthase	-
DQM48_RS06025 (NCTC8738_01255)	-	1155220..1156491 (+)	1272	WP_111698837.1	hydroxymethylglutaryl-CoA reductase, degradative	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 45224.79 Da
• Isoelectric Point: 4.5119

>NTDB_id=1137826 DQM48_RS06000 WP_020916897.1 1150855..1152084(-) (clpX) [Streptococcus lutetiensis strain NCTC8738]
MVGNRTNDVKVYCSFCGKSQDEVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLAEVPKPKELLATLDEYVVGQER
AKRALAVAVYNHYKRVSFAESRDEEDVELQKSNILLIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQINTK
NILFIVGGAFDGIEDIVKQRLGEKVIGFGQNNRKIDEDASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLTTDDLVRI
LTEPRNALVKQYQTLLSYDGVELEFDEDALQAIANKAIERKTGARGLRSIIEETMMDIMFEIPSRVEVTKVRITKDAVEG
KDKPILEIA

Nucleotide

• Length: 1230 bp

>NTDB_id=1137826 DQM48_RS06000 WP_020916897.1 1150855..1152084(-) (clpX) [Streptococcus lutetiensis strain NCTC8738]
ATGGTTGGAAATCGAACAAATGATGTAAAAGTTTATTGCTCATTTTGTGGAAAAAGCCAAGACGAAGTAAAAAAAATCAT
TGCCGGAAATAACGTATTTATCTGTAATGAATGTGTGGCTTTATCCCAAGAAATTATTAAAGAGGAGTTAGCAGAAGAAG
TTCTCGCAGATTTGGCTGAAGTTCCAAAACCAAAAGAATTATTAGCAACCCTCGATGAATATGTTGTCGGTCAAGAACGC
GCTAAACGTGCCCTCGCAGTGGCTGTATACAACCACTACAAACGTGTTTCATTTGCCGAAAGTCGTGATGAAGAAGATGT
TGAATTGCAAAAATCTAACATCTTATTGATTGGACCAACTGGTTCAGGGAAAACTTTCCTTGCTCAAACCTTGGCGAAAA
GTTTAAACGTTCCATTTGCGATTGCTGATGCGACATCATTGACAGAAGCAGGATACGTTGGTGAAGACGTTGAAAATATC
CTTTTGAAACTCATTCAAGCAGCTGATTTTAATATTGAACGCGCAGAACGTGGTATCATCTACGTGGATGAAATTGATAA
AATTGCCAAAAAAGGTGAAAATGTCTCAATCACTCGTGATGTTTCAGGCGAAGGTGTTCAACAAGCTCTTCTTAAAATTA
TTGAAGGAACAGTTGCTAGCGTGCCACCACAAGGTGGTCGTAAACACCCGAACCAAGAAATGATTCAAATCAATACTAAG
AATATCCTTTTCATCGTTGGTGGTGCTTTTGACGGTATTGAAGATATTGTTAAACAACGTCTCGGTGAAAAAGTTATTGG
TTTTGGTCAAAATAACCGTAAGATCGATGAAGATGCTTCTTATATGCAAGAAATTATCTCGGAAGATATTCAGAAATTTG
GTTTAATTCCTGAATTTATCGGACGTTTGCCAGTCGTTGCTGCCCTTGAACAATTGACAACAGATGATTTGGTACGAATC
TTGACAGAACCTCGTAATGCCTTGGTTAAACAATACCAAACGCTTCTATCATATGATGGTGTTGAGTTGGAATTTGATGA
AGATGCCCTTCAAGCTATTGCTAATAAAGCAATCGAACGTAAGACAGGTGCACGTGGACTTCGTTCAATCATTGAAGAAA
CAATGATGGATATCATGTTTGAAATTCCAAGTCGTGTAGAGGTCACTAAAGTCCGTATTACAAAAGATGCCGTTGAAGGC
AAAGATAAACCAATTTTAGAGATTGCCTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-390)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	88.998	100	0.89
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.853	98.044	0.577