Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   DQM73_RS05505 Genome accession   NZ_LS483346
Coordinates   1121537..1122766 (+) Length   409 a.a.
NCBI ID   WP_002924853.1    Uniprot ID   A0A2X3VMN2
Organism   Streptococcus sanguinis strain NCTC11085     
Function   require for competence development (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1118244..1131154 1121537..1122766 within 0


Gene organization within MGE regions


Location: 1118244..1131154
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM73_RS05475 (NCTC11085_01072) - 1118244..1118654 (+) 411 WP_032908181.1 GNAT family N-acetyltransferase -
  DQM73_RS05485 (NCTC11085_01073) - 1118767..1119726 (+) 960 WP_002924859.1 ROK family glucokinase -
  DQM73_RS05490 (NCTC11085_01074) - 1119831..1120670 (+) 840 WP_002924857.1 thymidylate synthase -
  DQM73_RS05495 (NCTC11085_01075) - 1120795..1121307 (+) 513 WP_002924855.1 dihydrofolate reductase -
  DQM73_RS05500 (NCTC11085_01076) - 1121310..1121480 (+) 171 WP_002895584.1 hypothetical protein -
  DQM73_RS05505 (NCTC11085_01077) clpX 1121537..1122766 (+) 1230 WP_002924853.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  DQM73_RS05510 (NCTC11085_01078) yihA 1122777..1123364 (+) 588 WP_002924843.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  DQM73_RS05515 (NCTC11085_01079) - 1123512..1124210 (+) 699 WP_002924833.1 glucosaminidase domain-containing protein -
  DQM73_RS05520 (NCTC11085_01080) mmuM 1124332..1125279 (+) 948 WP_002924831.1 homocysteine S-methyltransferase -
  DQM73_RS05525 (NCTC11085_01081) - 1125392..1126189 (+) 798 WP_002924829.1 formate/nitrite transporter family protein -
  DQM73_RS05535 (NCTC11085_01082) - 1126947..1127663 (+) 717 WP_231908375.1 hypothetical protein -
  DQM73_RS05545 (NCTC11085_01083) - 1127871..1128500 (+) 630 WP_002924821.1 hypothetical protein -
  DQM73_RS05555 (NCTC11085_01085) rplJ 1128784..1129284 (+) 501 WP_002895572.1 50S ribosomal protein L10 -
  DQM73_RS05560 (NCTC11085_01086) rplL 1129358..1129726 (+) 369 WP_002895571.1 50S ribosomal protein L7/L12 -
  DQM73_RS05565 (NCTC11085_01087) - 1129859..1131154 (+) 1296 WP_197709055.1 hypothetical protein -

Sequence

Protein


Download         Length: 409 a.a.        Molecular weight: 45601.05 Da        Isoelectric Point: 4.4012

>NTDB_id=1137704 DQM73_RS05505 WP_002924853.1 1121537..1122766(+) (clpX) [Streptococcus sanguinis strain NCTC11085]
MPTSRNDDMMVFCSFCGKNQDEVQKIIAGNNAFICNECVELAQEIIREELAEEVLADLSEVPKPQELLNILNHYVIGQDR
AKRALAVAVYNHYKRINYHDSREEEDVELQKSNILMIGPTGSGKTFLAQTLARSLNVPFAIADATALTEAGYVGEDVENI
LLKLLQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDTK
NILFIVGGAFDGIEEIVKQRLGEKIIGFGQNNRAIDEDGSYMQEIISEDVQKFGIIPELIGRLPVFAALEQLTVDDLVRI
LKEPRNALIKQYQALLSYDDVKLEFDEEALQEIANKAIERKTGARGLRSIIEETMMDVMFEVPSQENVKLVRITKEAVDG
TDKPILETA

Nucleotide


Download         Length: 1230 bp        

>NTDB_id=1137704 DQM73_RS05505 WP_002924853.1 1121537..1122766(+) (clpX) [Streptococcus sanguinis strain NCTC11085]
ATGCCTACAAGTCGTAATGATGATATGATGGTTTTTTGTTCTTTCTGTGGGAAGAACCAAGATGAGGTGCAGAAGATTAT
CGCTGGTAACAATGCCTTTATCTGCAATGAATGTGTGGAGCTTGCGCAGGAAATCATCCGTGAAGAGCTAGCTGAGGAAG
TGCTAGCAGATCTGTCTGAGGTACCAAAACCTCAGGAGCTGCTGAATATCTTGAACCACTATGTTATTGGGCAAGACCGA
GCTAAGCGTGCCTTAGCGGTAGCGGTCTATAATCACTACAAGCGTATTAACTACCACGACAGCCGAGAAGAAGAAGATGT
GGAACTGCAAAAGTCAAATATTTTGATGATTGGCCCGACTGGGTCAGGTAAGACCTTCCTGGCGCAGACTCTGGCTCGCA
GTCTCAATGTGCCTTTTGCCATTGCGGACGCAACTGCTCTGACTGAAGCTGGTTATGTCGGTGAAGATGTGGAAAATATC
CTCCTCAAGCTTTTGCAGGCGGCTGACTTTAATATTGAGCGTGCAGAACGCGGCATTATCTATGTCGATGAGATTGACAA
AATTGCCAAGAAAGGTGAGAACGTCTCTATTACTCGTGATGTTTCAGGAGAAGGAGTTCAACAAGCTCTTCTGAAGATTA
TCGAAGGAACAGTAGCTAGTGTGCCGCCGCAAGGTGGACGTAAGCATCCGCAGCAGGAAATGATTCAGGTTGATACCAAG
AATATTCTCTTCATTGTTGGCGGTGCTTTTGACGGTATTGAAGAAATCGTAAAACAGCGTCTGGGTGAGAAAATCATTGG
TTTCGGTCAGAATAACCGAGCGATTGACGAAGATGGGTCCTATATGCAGGAAATTATCTCAGAAGACGTTCAAAAGTTTG
GAATTATCCCTGAGTTGATTGGCCGTTTGCCTGTTTTTGCTGCCCTGGAGCAACTGACAGTTGATGATTTGGTTCGGATT
TTGAAAGAGCCGAGAAATGCTCTTATCAAGCAGTATCAAGCACTTCTATCCTACGATGATGTGAAGCTTGAATTTGACGA
AGAGGCTCTGCAGGAAATTGCCAATAAGGCGATTGAACGTAAAACTGGTGCGCGCGGTCTTCGCTCTATCATTGAAGAAA
CTATGATGGATGTCATGTTTGAAGTTCCGAGTCAGGAAAATGTCAAACTTGTCCGCATTACCAAAGAAGCAGTAGATGGA
ACAGATAAGCCTATTCTAGAAACTGCCTAA

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(312-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(110-305)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2X3VMN2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

85.819

100

0.858
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.357

98.044

0.562

Multiple sequence alignment