Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   DQL69_RS03090 Genome accession   NZ_LS483345
Coordinates   591191..592228 (+) Length   345 a.a.
NCBI ID   WP_111690739.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC8231     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 586191..597228
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL69_RS03065 (NCTC8231_00598) - 586455..587786 (+) 1332 WP_011054719.1 dipeptidase -
  DQL69_RS03070 (NCTC8231_00599) arcC 587806..588756 (+) 951 WP_011528820.1 carbamate kinase -
  DQL69_RS03075 (NCTC8231_00600) asnA 589069..590061 (+) 993 WP_002983817.1 aspartate--ammonia ligase -
  DQL69_RS03080 (NCTC8231_00601) rsmD 590184..590723 (+) 540 WP_002983819.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  DQL69_RS03085 (NCTC8231_00602) coaD 590713..591204 (+) 492 WP_002983821.1 pantetheine-phosphate adenylyltransferase -
  DQL69_RS03090 (NCTC8231_00603) sepM 591191..592228 (+) 1038 WP_111690739.1 SepM family pheromone-processing serine protease Regulator
  DQL69_RS03095 (NCTC8231_00604) - 592642..593619 (+) 978 WP_002994809.1 LacI family DNA-binding transcriptional regulator -
  DQL69_RS03100 (NCTC8231_00605) - 594121..594741 (+) 621 WP_032464468.1 YutD family protein -
  DQL69_RS03105 (NCTC8231_00606) rlmN 594745..595824 (+) 1080 WP_002992788.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  DQL69_RS03110 (NCTC8231_00607) - 595906..596532 (-) 627 WP_002983834.1 prepilin peptidase -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 37569.30 Da        Isoelectric Point: 9.6692

>NTDB_id=1137647 DQL69_RS03090 WP_111690739.1 591191..592228(+) (sepM) [Streptococcus pyogenes strain NCTC8231]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDADFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKAVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRA
AKRLKTKMKIVPITTVQEALVYLRK

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=1137647 DQL69_RS03090 WP_111690739.1 591191..592228(+) (sepM) [Streptococcus pyogenes strain NCTC8231]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGGGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCTCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATGCTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGTTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGGGATGAAGTTACGGTTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGCAGTAGGAGGACCTAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGGCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTATTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(129-192)

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(233-309)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

68.696

100

0.687

Multiple sequence alignment