Detailed information    

insolico Bioinformatically predicted

Overview

Name   hdrM   Type   Regulator
Locus tag   DQL21_RS08170 Genome accession   NZ_LS483343
Coordinates   1575778..1576467 (+) Length   229 a.a.
NCBI ID   WP_018030690.1    Uniprot ID   A0A2X3W1A8
Organism   Streptococcus ferus strain NCTC12278     
Function   repress competence development; negative regulate HdrR activity (predicted from homology)   
Competence regulation

Genomic Context

Location: 1570778..1581467
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL21_RS08155 (NCTC12278_01632) uvrA 1571073..1573898 (-) 2826 WP_018030693.1 excinuclease ABC subunit UvrA -
  DQL21_RS08160 (NCTC12278_01633) - 1574034..1574978 (+) 945 WP_018030692.1 magnesium transporter CorA family protein -
  DQL21_RS08165 (NCTC12278_01634) - 1575018..1575695 (+) 678 WP_018030691.1 DUF1129 domain-containing protein -
  DQL21_RS08170 (NCTC12278_01635) hdrM 1575778..1576467 (+) 690 WP_018030690.1 LiaF domain-containing protein Regulator
  DQL21_RS08175 (NCTC12278_01636) rpsR 1576520..1576759 (-) 240 WP_018030689.1 30S ribosomal protein S18 -
  DQL21_RS08180 (NCTC12278_01637) ssb 1576859..1577353 (-) 495 WP_018030688.1 single-stranded DNA-binding protein Machinery gene
  DQL21_RS08185 (NCTC12278_01638) rpsF 1577365..1577655 (-) 291 WP_018030687.1 30S ribosomal protein S6 -
  DQL21_RS08190 (NCTC12278_01639) mutY 1578507..1579658 (+) 1152 WP_026161971.1 A/G-specific adenine glycosylase -
  DQL21_RS08195 (NCTC12278_01640) trxA 1579676..1579990 (-) 315 WP_018030685.1 thioredoxin -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 25714.63 Da        Isoelectric Point: 6.6062

>NTDB_id=1137612 DQL21_RS08170 WP_018030690.1 1575778..1576467(+) (hdrM) [Streptococcus ferus strain NCTC12278]
MKKNHFGIAVLVLLAAYLITTAFVPDLQVIFNSLLVLAIFFTTLGLSHKNMVVFFMGLGFLAIYLKDVFNFTYSSGPLFA
GLVILGVILNYFIKPKYKTQYSSDSDHFFQDAEVAHIDSQSQVTLKTFFSENAYYVTSQNLERITINVKFGEQNIDLTQA
QFLTAYPQIYLDVHFGEANIRIPRHWKISNQTNHPLASVSVSGFQTEAEDAVTVELLGTAAMAAVNIRY

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1137612 DQL21_RS08170 WP_018030690.1 1575778..1576467(+) (hdrM) [Streptococcus ferus strain NCTC12278]
ATGAAAAAGAATCATTTTGGCATTGCTGTCTTGGTCTTACTGGCAGCCTACCTTATCACAACAGCCTTTGTACCCGATTT
ACAAGTGATTTTCAACAGCCTGCTGGTTCTGGCAATTTTCTTCACCACACTAGGCCTCAGTCATAAAAATATGGTTGTTT
TCTTTATGGGTCTTGGTTTTTTAGCCATTTACCTCAAGGATGTTTTTAATTTCACCTACTCAAGCGGTCCGCTTTTTGCT
GGACTTGTCATTCTGGGAGTTATTCTGAATTATTTTATCAAACCCAAATACAAGACTCAGTATTCATCCGACTCTGATCA
CTTCTTTCAGGACGCAGAGGTCGCCCATATTGACAGCCAAAGTCAGGTCACTTTAAAAACGTTCTTTTCGGAAAATGCCT
ACTATGTGACCTCTCAGAATCTTGAAAGAATCACTATCAATGTTAAATTTGGCGAACAAAATATTGACCTCACTCAGGCA
CAGTTTCTAACCGCCTATCCCCAGATTTATCTAGATGTTCATTTTGGCGAGGCTAATATCAGGATTCCTAGACACTGGAA
AATCAGCAACCAGACGAACCACCCACTGGCATCTGTTTCCGTCAGCGGTTTTCAGACCGAGGCTGAAGATGCGGTCACCG
TAGAGCTTCTGGGTACTGCCGCCATGGCTGCTGTCAACATTAGATACTAA

Domains

Predicted by InterproScan.

Cell wall-active antibiotics response 4TMS YvqF (LiaF-like_C)

(128-205)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2X3W1A8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hdrM Streptococcus mutans UA159

53.043

100

0.533

Multiple sequence alignment