Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   DQL21_RS05200 Genome accession   NZ_LS483343
Coordinates   1003224..1004456 (-) Length   410 a.a.
NCBI ID   WP_018029889.1    Uniprot ID   A0A2X3Y0Z5
Organism   Streptococcus ferus strain NCTC12278     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 998224..1009456
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL21_RS05180 (NCTC12278_01028) - 998914..1000173 (+) 1260 WP_018029885.1 PLP-dependent aminotransferase family protein -
  DQL21_RS05185 (NCTC12278_01029) mmuM 1000188..1001138 (-) 951 WP_018029886.1 homocysteine S-methyltransferase -
  DQL21_RS05190 (NCTC12278_01030) - 1001148..1002524 (-) 1377 WP_018029887.1 amino acid permease -
  DQL21_RS05195 (NCTC12278_01031) yihA 1002626..1003213 (-) 588 WP_018029888.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  DQL21_RS05200 (NCTC12278_01032) clpX 1003224..1004456 (-) 1233 WP_018029889.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  DQL21_RS05210 (NCTC12278_01034) - 1004669..1005169 (-) 501 WP_018029890.1 dihydrofolate reductase -
  DQL21_RS05215 (NCTC12278_01035) - 1005252..1006091 (-) 840 WP_018029891.1 thymidylate synthase -
  DQL21_RS05220 (NCTC12278_01036) - 1006313..1007497 (+) 1185 WP_026161894.1 hydroxymethylglutaryl-CoA synthase -
  DQL21_RS05225 (NCTC12278_01037) - 1007484..1008776 (+) 1293 WP_018029893.1 hydroxymethylglutaryl-CoA reductase, degradative -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 45337.74 Da        Isoelectric Point: 4.4500

>NTDB_id=1137600 DQL21_RS05200 WP_018029889.1 1003224..1004456(-) (clpX) [Streptococcus ferus strain NCTC12278]
MTGTRTNDVTVHCSFCGKSQDEVRKIIAGNGVFICNECVELSQEIIREELSEEVLSDLAEVPKPKELLDILNNYVIGQDR
AKRALAVAVYNHYKRVSFTESRDEEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENI
LLKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKIIGFGQSNRKIDDQASYMQEIISEDIQKFGLIPEFIGRLPVIAALEQLTVDDLVKI
LTEPRNALVKQYQTLLSYDGVELEFDREALEAIAQKAIERKTGARGLRSIIEETMLDIMFEIPSEEDVTSVRITKAAVDG
RDKPILETAS

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=1137600 DQL21_RS05200 WP_018029889.1 1003224..1004456(-) (clpX) [Streptococcus ferus strain NCTC12278]
ATGACTGGAACAAGAACTAACGATGTCACTGTCCACTGCTCATTCTGTGGCAAAAGTCAGGACGAAGTAAGAAAAATCAT
TGCTGGTAACGGCGTTTTCATCTGTAATGAATGTGTCGAATTGTCACAAGAGATTATTCGTGAGGAATTGTCTGAAGAAG
TCCTGTCAGACTTGGCAGAAGTCCCTAAACCGAAAGAACTACTGGATATTCTCAATAATTATGTCATTGGTCAGGATCGT
GCCAAACGGGCTTTGGCTGTTGCTGTCTATAACCACTACAAGCGTGTCAGCTTTACTGAGAGCCGCGATGAAGAAGATGT
TGATTTGCAAAAGTCCAACATCCTGATGATCGGCCCTACCGGTTCAGGCAAGACGTTCTTGGCGCAGACACTAGCTAAGA
GCCTCAATGTTCCATTTGCGATTGCAGATGCGACAGCTTTGACCGAGGCCGGTTATGTTGGAGAAGATGTTGAAAACATT
TTGCTTAAGCTGATTCAGGCTGCTGATTTTAATATTGAACGTGCGGAACGTGGCATTATCTATGTAGATGAGATTGATAA
GATTGCTAAGAAAGGCGAGAACGTCTCAATCACCCGAGATGTTTCAGGTGAAGGTGTTCAGCAGGCCTTACTTAAAATTA
TTGAAGGTACGGTTGCCAGTGTTCCCCCACAAGGAGGGCGCAAGCATCCGCAGCAAGAGATGATTCAAATCGATACGAAG
AATATCCTCTTCATCGTTGGAGGTGCCTTTGACGGGATCGAAGAAATCGTCAAACAGCGCCTCGGTGAGAAAATTATCGG
ATTCGGTCAGTCCAACCGCAAAATTGATGATCAGGCTTCTTATATGCAGGAAATTATCTCCGAGGACATTCAAAAATTTG
GTCTTATTCCAGAGTTCATCGGTCGTCTGCCAGTTATTGCAGCTCTTGAGCAGCTGACAGTTGACGACTTGGTTAAAATT
CTGACAGAGCCCAGAAATGCTCTGGTGAAACAGTATCAAACCCTCCTGTCTTATGACGGTGTAGAATTAGAATTTGACAG
AGAGGCTTTAGAAGCGATTGCTCAGAAAGCTATTGAACGTAAAACAGGTGCTCGCGGCCTTCGCTCTATTATTGAGGAAA
CCATGCTGGATATCATGTTTGAAATTCCAAGTGAGGAAGATGTTACCTCTGTCCGTATTACCAAGGCTGCCGTTGATGGC
CGTGATAAGCCTATTTTAGAAACAGCTTCTTAA

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

AAA domain (Cdc48 subfamily) (AAA_2)

(110-306)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(312-390)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2X3Y0Z5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

92.683

100

0.927
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.855

97.805

0.566

Multiple sequence alignment