Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   DQL21_RS02340 Genome accession   NZ_LS483343
Coordinates   433240..434538 (+) Length   432 a.a.
NCBI ID   WP_018030897.1    Uniprot ID   A0A2X3VJ97
Organism   Streptococcus ferus strain NCTC12278     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 428240..439538
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL21_RS02310 (NCTC12278_00446) - 428646..429287 (+) 642 WP_018030903.1 response regulator transcription factor -
  DQL21_RS02315 (NCTC12278_00447) - 429322..430719 (+) 1398 WP_018030902.1 Cof-type HAD-IIB family hydrolase -
  DQL21_RS02320 (NCTC12278_00448) - 430719..431075 (+) 357 WP_018030901.1 S1 RNA-binding domain-containing protein -
  DQL21_RS02325 (NCTC12278_00449) cysK 431139..432065 (-) 927 WP_018030900.1 cysteine synthase A -
  DQL21_RS02330 - 432295..432498 (+) 204 WP_018030899.1 cold-shock protein -
  DQL21_RS02335 - 432544..433173 (-) 630 WP_018030898.1 YigZ family protein -
  DQL21_RS02340 (NCTC12278_00451) comFA/cflA 433240..434538 (+) 1299 WP_018030897.1 DEAD/DEAH box helicase Machinery gene
  DQL21_RS02345 (NCTC12278_00452) - 434538..435200 (+) 663 WP_018030896.1 ComF family protein -
  DQL21_RS02350 (NCTC12278_00453) hpf 435277..435828 (+) 552 WP_018030895.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  DQL21_RS02355 (NCTC12278_00454) - 435972..437102 (+) 1131 WP_018030894.1 hypothetical protein -
  DQL21_RS02360 (NCTC12278_00455) - 437112..438773 (+) 1662 WP_018030893.1 zinc ribbon domain-containing protein -
  DQL21_RS02365 (NCTC12278_00456) - 439072..439458 (+) 387 WP_018030892.1 hypothetical protein -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 48827.67 Da        Isoelectric Point: 9.1953

>NTDB_id=1137585 DQL21_RS02340 WP_018030897.1 433240..434538(+) (comFA/cflA) [Streptococcus ferus strain NCTC12278]
MERLEQYCGRLLTADQLPAAYHELAQKMPAMTKKSGHFFCNRCAGQVENTHRLPDGSFYCRACLVFGRLTSKDSLYWLEQ
KAFPAQQALLWEGQLTAFQQEVSDALLAGIQEKTDLLVHAVTGAGKTEMIYETIAHVVSQGGSVALASPRIDVCLELHRR
LQKDFACPISLLHGQSEAYERAPLLIATTHQLIKFYQAFDLLIIDEVDAFPFVDNPMLYHALNQSLKTDGVKIFLTATST
QELDRQVKKGQLKKINLARRFHANPLVVPKTVWLPSLIPGLKKRRLPKTLLKRLQVQRKTGFPLLLFFPNIDRGQAFAEC
LQEFLPNDKIAFVSSRTESRLDKVEAFRKKEIDILVSTTILERGVTFPCVDVFVLEANHRLFTKSALVQISGRTGRSIER
PTGELLFFHDGLTTAIQQTISEIKEMNRRGGF

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=1137585 DQL21_RS02340 WP_018030897.1 433240..434538(+) (comFA/cflA) [Streptococcus ferus strain NCTC12278]
ATGGAAAGACTAGAACAGTATTGTGGACGACTGCTGACCGCTGATCAGCTTCCGGCAGCCTACCATGAATTGGCACAAAA
GATGCCGGCAATGACGAAAAAATCAGGTCATTTTTTCTGTAATCGCTGTGCCGGTCAGGTAGAAAACACACACCGTTTGC
CTGATGGCAGTTTCTATTGCAGAGCCTGCCTTGTTTTTGGTCGTCTGACCAGTAAGGATAGTCTCTATTGGCTAGAGCAA
AAAGCTTTTCCAGCCCAGCAGGCGCTTTTATGGGAGGGGCAGTTAACCGCTTTTCAGCAGGAAGTATCCGATGCGCTGTT
GGCGGGTATTCAGGAAAAAACGGATTTGTTGGTTCACGCCGTAACAGGTGCTGGTAAAACAGAAATGATATATGAGACGA
TTGCCCATGTCGTTAGCCAAGGAGGGTCTGTCGCTCTAGCCAGTCCTAGAATCGATGTTTGTTTAGAACTGCATCGGCGG
CTGCAAAAAGATTTTGCCTGTCCGATTTCTCTGCTCCATGGTCAATCAGAAGCCTATGAGAGGGCTCCCTTGCTGATTGC
AACAACACATCAGTTAATCAAATTTTATCAGGCTTTTGATCTTTTAATCATTGATGAAGTTGATGCCTTTCCTTTTGTGG
ACAATCCGATGCTTTATCATGCGCTCAACCAATCCCTTAAAACGGATGGGGTTAAAATTTTTCTGACGGCCACCTCAACA
CAAGAACTAGATAGGCAGGTCAAAAAAGGTCAGCTAAAGAAAATCAACTTAGCCAGACGCTTTCATGCGAATCCCCTTGT
TGTTCCGAAGACGGTCTGGCTCCCGTCACTAATTCCCGGTCTGAAAAAGAGGCGCCTCCCAAAAACCTTGTTGAAGAGAC
TGCAGGTGCAGAGAAAGACAGGTTTTCCCTTATTGCTTTTCTTTCCAAATATTGACCGAGGACAAGCGTTTGCTGAATGT
CTGCAAGAATTCCTGCCCAATGACAAAATCGCCTTTGTCTCAAGTCGAACAGAAAGTCGCCTGGACAAGGTAGAAGCTTT
CCGAAAAAAGGAAATTGATATTTTAGTCTCCACCACTATATTGGAGCGTGGAGTGACCTTTCCCTGTGTTGATGTCTTTG
TTTTGGAGGCTAACCATCGTCTGTTCACAAAATCAGCCTTAGTTCAGATTTCAGGCCGTACCGGCCGGTCTATTGAAAGA
CCGACAGGTGAGCTTTTGTTTTTTCACGATGGGCTTACCACAGCCATTCAACAAACGATTTCAGAAATTAAAGAGATGAA
TCGAAGAGGAGGGTTTTAG

Domains

Predicted by InterproScan.

DEAD/DEAH box helicase (DEAD)

(96-243)

Helicase conserved C-terminal domain (Helicase_C)

(291-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2X3VJ97

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

59.953

98.843

0.593
  comFA/cflA Streptococcus pneumoniae Rx1

59.155

98.611

0.583
  comFA/cflA Streptococcus pneumoniae D39

59.155

98.611

0.583
  comFA/cflA Streptococcus pneumoniae R6

59.155

98.611

0.583
  comFA/cflA Streptococcus pneumoniae TIGR4

59.155

98.611

0.583
  comFA/cflA Streptococcus mitis SK321

58.314

98.843

0.576
  comFA Lactococcus lactis subsp. cremoris KW2

52.451

94.444

0.495
  comFA Latilactobacillus sakei subsp. sakei 23K

41.379

100

0.417

Multiple sequence alignment