Detailed information NTG1137495

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: DQL23_RS07315
• Genome accession: NZ_LS483341
• Coordinates: 1506107..1507336 (+)
• Length: 409 a.a.
• NCBI ID: WP_008808666.1
• Uniprot ID: A0AAP2K4Q6
• Organism: Streptococcus gordonii strain NCTC7865
• Function: require for competence development (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Prophage	1482605..1510605	1506107..1507336	within	0

Gene organization within MGE regions

Location: 1482605..1510605

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL23_RS07220 (NCTC7865_01458)	guaC	1482605..1483588 (+)	984	WP_008808651.1	GMP reductase	-
DQL23_RS07225 (NCTC7865_01459)	-	1483769..1484350 (+)	582	WP_008808652.1	xanthine phosphoribosyltransferase	-
DQL23_RS07230 (NCTC7865_01460)	-	1484352..1485617 (+)	1266	WP_037622361.1	nucleobase:cation symporter-2 family protein	-
DQL23_RS07235 (NCTC7865_01461)	-	1485731..1485913 (-)	183	WP_060553585.1	4-oxalocrotonate tautomerase	-
DQL23_RS07240 (NCTC7865_01462)	-	1486035..1486610 (+)	576	WP_045503019.1	thymidine kinase	-
DQL23_RS07245 (NCTC7865_01463)	prfA	1486643..1487722 (+)	1080	WP_060553586.1	peptide chain release factor 1	-
DQL23_RS07250 (NCTC7865_01464)	prmC	1487722..1488552 (+)	831	WP_060553587.1	peptide chain release factor N(5)-glutamine methyltransferase	-
DQL23_RS07255 (NCTC7865_01465)	-	1488545..1489135 (+)	591	WP_060553588.1	L-threonylcarbamoyladenylate synthase	-
DQL23_RS07260 (NCTC7865_01466)	glyA	1489183..1490445 (+)	1263	WP_045503008.1	serine hydroxymethyltransferase	-
DQL23_RS07265 (NCTC7865_01467)	-	1490447..1491421 (+)	975	WP_060553589.1	nucleoid-associated protein	-
DQL23_RS07270 (NCTC7865_01468)	-	1491421..1492023 (+)	603	WP_046165585.1	lysozyme family protein	-
DQL23_RS07275 (NCTC7865_01469)	-	1492204..1500297 (+)	8094	WP_111705895.1	GEVED domain-containing protein	-
DQL23_RS07280	-	1500412..1501624 (+)	1213	Protein_1430	IS3 family transposase	-
DQL23_RS07285 (NCTC7865_01472)	-	1501692..1502537 (+)	846	WP_060553598.1	alpha/beta hydrolase	-
DQL23_RS07290 (NCTC7865_01473)	-	1502712..1503671 (+)	960	WP_060553599.1	ROK family glucokinase	-
DQL23_RS07295 (NCTC7865_01474)	-	1503770..1504609 (+)	840	WP_060553600.1	thymidylate synthase	-
DQL23_RS07300 (NCTC7865_01475)	-	1504740..1505240 (+)	501	WP_060553601.1	hypothetical protein	-
DQL23_RS07305 (NCTC7865_01476)	-	1505386..1505898 (+)	513	WP_060553602.1	dihydrofolate reductase	-
DQL23_RS07315 (NCTC7865_01477)	clpX	1506107..1507336 (+)	1230	WP_008808666.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
DQL23_RS07320 (NCTC7865_01478)	yihA	1507346..1507939 (+)	594	WP_048779982.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
DQL23_RS07325 (NCTC7865_01479)	-	1508073..1508762 (+)	690	WP_012000547.1	glucosaminidase domain-containing protein	-
DQL23_RS07330 (NCTC7865_01480)	-	1508890..1509687 (+)	798	WP_060954898.1	formate/nitrite transporter family protein	-
DQL23_RS07335 (NCTC7865_01481)	-	1509781..1510605 (+)	825	WP_060553604.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 45650.21 Da
• Isoelectric Point: 4.4870

>NTDB_id=1137495 DQL23_RS07315 WP_008808666.1 1506107..1507336(+) (clpX) [Streptococcus gordonii strain NCTC7865]
MPTNRNEEMMVYCSFCGKNQDEVQKIIAGNNAFICNECVELAQEIIREELAEEVLADLSEVPKPQELLHILNHYVIGQER
AKRALAVAVYNHYKRINFHDSREEDDVELQKSNILMIGPTGSGKTFLAQTLARSLNVPFAIADATALTEAGYVGEDVENI
LLKLLQAADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDTK
NILFIVGGAFDGIEEIVKQRLGEKIIGFGQNNKAIDENESYMQAIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRI
LREPKNALVKQYQALLSYDDVKLEFDDDALQEIANKAIERKTGARGLRSIIEETMMDVMFEVPSKENVKLVRITKEAVDG
TDKPILETA

Nucleotide

• Length: 1230 bp

>NTDB_id=1137495 DQL23_RS07315 WP_008808666.1 1506107..1507336(+) (clpX) [Streptococcus gordonii strain NCTC7865]
ATGCCTACCAATCGTAATGAAGAGATGATGGTATATTGTTCATTTTGTGGGAAGAACCAAGATGAAGTTCAAAAGATTAT
TGCAGGTAATAACGCTTTTATTTGTAATGAGTGTGTAGAATTAGCGCAAGAAATTATCCGTGAAGAATTGGCCGAAGAAG
TCTTAGCTGACTTGTCAGAGGTTCCAAAACCTCAAGAATTATTGCATATTCTAAACCATTATGTCATCGGCCAAGAGCGT
GCTAAAAGAGCGCTAGCTGTAGCGGTATATAATCACTACAAGCGTATTAATTTTCATGACAGTCGCGAAGAAGACGATGT
TGAATTACAAAAATCAAATATTTTAATGATCGGTCCAACGGGTTCTGGAAAAACTTTTCTTGCTCAAACCTTGGCTAGAA
GTTTAAATGTGCCATTTGCGATTGCTGATGCGACAGCATTAACAGAGGCTGGTTATGTCGGAGAAGATGTAGAAAATATT
CTTTTAAAACTTTTACAGGCGGCTGATTTCAATATTGAACGTGCAGAACGCGGAATTATCTACGTTGATGAGATTGATAA
GATCGCTAAAAAAAGTGAAAATGTTTCTATCACGCGCGATGTATCAGGTGAAGGAGTACAGCAAGCACTCTTAAAAATTA
TCGAGGGTACTGTAGCAAGTGTTCCGCCTCAAGGAGGTCGCAAGCATCCGCAGCAAGAAATGATTCAAGTTGATACCAAA
AATATTCTTTTCATCGTTGGTGGTGCCTTTGATGGAATTGAAGAAATTGTTAAACAACGTTTGGGCGAGAAAATTATTGG
TTTTGGTCAAAATAACAAAGCTATTGATGAAAACGAGTCCTACATGCAGGCTATTATTGCCGAAGATATTCAAAAATTTG
GAATTATCCCTGAATTAATTGGTCGTTTGCCTGTTTTTGCTGCTCTGGAACAACTGACTGTAGATGACTTGGTTCGTATT
CTTCGTGAACCTAAGAATGCTTTGGTTAAACAATACCAAGCTCTCTTGTCTTATGATGATGTTAAACTAGAGTTTGATGA
TGATGCTTTACAGGAAATCGCGAACAAGGCCATTGAGCGCAAAACTGGTGCTCGCGGTCTACGTTCTATCATCGAAGAAA
CCATGATGGATGTTATGTTTGAAGTTCCAAGTAAAGAAAATGTGAAACTTGTCAGAATTACGAAGGAAGCCGTTGATGGT
ACGGATAAACCAATTTTAGAGACTGCTTGA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-389)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	85.575	100	0.856
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.105	98.044	0.57