Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   DQL23_RS02340 Genome accession   NZ_LS483341
Coordinates   503032..503721 (+) Length   229 a.a.
NCBI ID   WP_045505796.1    Uniprot ID   A0AAW3H5C9
Organism   Streptococcus gordonii strain NCTC7865     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 498032..508721
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL23_RS02320 (NCTC7865_00461) - 498377..499246 (-) 870 WP_060552995.1 Rgg/GadR/MutR family transcriptional regulator -
  DQL23_RS02325 (NCTC7865_00462) - 499345..499875 (+) 531 WP_012000007.1 YceD family protein -
  DQL23_RS02330 (NCTC7865_00463) - 499978..501459 (+) 1482 WP_060552994.1 flotillin family protein -
  DQL23_RS02335 (NCTC7865_00464) gndA 501595..503019 (+) 1425 WP_060552993.1 NADP-dependent phosphogluconate dehydrogenase -
  DQL23_RS02340 (NCTC7865_00465) covR 503032..503721 (+) 690 WP_045505796.1 response regulator transcription factor Regulator
  DQL23_RS02345 (NCTC7865_00466) - 504079..506271 (+) 2193 WP_060552992.1 PTS transporter subunit IIBC -
  DQL23_RS02350 (NCTC7865_00467) - 506289..507104 (+) 816 WP_045505802.1 endonuclease/exonuclease/phosphatase family protein -
  DQL23_RS02355 (NCTC7865_00468) - 507247..507663 (-) 417 WP_060552991.1 hypothetical protein -
  DQL23_RS02360 (NCTC7865_00469) nrdR 507843..508316 (+) 474 WP_012000014.1 transcriptional regulator NrdR -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26275.27 Da        Isoelectric Point: 5.1861

>NTDB_id=1137451 DQL23_RS02340 WP_045505796.1 503032..503721(+) (covR) [Streptococcus gordonii strain NCTC7865]
MAKRILLVENEKNLARFIMLELQKESYQVDLAETGQEGLALAKENDYDLLLLNNQFADGTAFAFAQQLSLLKPAAVIIVM
VSREEIADSAEEIQQFAVSYMVKPFIISDLVDKISAIFRGRDFIDQRCSQLKVPTAYRNLRVDLKNHTVYRGDEIIALTR
REYDLLVTLMSSNKVMSREQLLDRVWKYESASETNIVDVYIRYLRSKIDLPGQESYIKTVRGIGYSMQG

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1137451 DQL23_RS02340 WP_045505796.1 503032..503721(+) (covR) [Streptococcus gordonii strain NCTC7865]
ATGGCGAAGCGGATTTTATTAGTTGAAAATGAAAAGAATCTAGCACGATTTATCATGCTGGAATTACAAAAGGAAAGTTA
TCAAGTAGACCTAGCGGAAACAGGCCAAGAGGGACTAGCTCTAGCAAAGGAAAACGATTATGATTTACTTTTACTAAATA
ATCAGTTTGCTGATGGAACAGCCTTTGCCTTTGCTCAACAATTGAGTTTATTAAAACCTGCTGCAGTTATCATTGTAATG
GTGAGTCGAGAGGAAATTGCGGATTCGGCTGAAGAGATTCAGCAGTTTGCAGTTTCTTATATGGTAAAACCCTTTATTAT
CAGTGATTTGGTTGATAAGATATCCGCTATTTTTCGTGGGCGGGATTTTATCGATCAGAGATGTAGCCAGTTAAAAGTCC
CTACTGCTTATCGAAATCTGCGGGTTGATTTGAAAAATCATACGGTTTATCGAGGGGATGAAATTATTGCTTTGACGAGA
CGAGAGTACGATTTACTAGTGACTCTAATGAGCAGTAATAAGGTGATGAGTCGTGAGCAACTGTTAGACCGAGTGTGGAA
ATATGAAAGTGCATCTGAAACGAATATAGTGGATGTATATATTCGCTATCTCCGCAGTAAAATCGATCTTCCAGGTCAAG
AAAGTTATATTAAAACCGTTCGTGGAATTGGTTATTCCATGCAGGGTTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

51.77

98.69

0.511
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.737

99.563

0.445

Multiple sequence alignment