Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   DQL28_RS05555 Genome accession   NZ_LS483334
Coordinates   1101979..1103208 (-) Length   409 a.a.
NCBI ID   WP_111676489.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC12050     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1096979..1108208
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL28_RS05535 (NCTC12050_01101) rpiA 1097261..1097944 (-) 684 WP_111676485.1 ribose-5-phosphate isomerase RpiA -
  DQL28_RS05540 (NCTC12050_01102) - 1098322..1100421 (+) 2100 WP_111676487.1 AAA family ATPase -
  DQL28_RS05545 (NCTC12050_01103) - 1100479..1101222 (-) 744 WP_002984942.1 hypothetical protein -
  DQL28_RS05550 (NCTC12050_01104) yihA 1101370..1101969 (-) 600 WP_011184414.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  DQL28_RS05555 (NCTC12050_01105) clpX 1101979..1103208 (-) 1230 WP_111676489.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  DQL28_RS05560 (NCTC12050_01106) - 1103338..1103508 (-) 171 WP_002990165.1 hypothetical protein -
  DQL28_RS05565 (NCTC12050_01107) - 1103528..1104025 (-) 498 WP_002984955.1 dihydrofolate reductase -
  DQL28_RS05570 (NCTC12050_01108) - 1104105..1104944 (-) 840 WP_011017679.1 thymidylate synthase -
  DQL28_RS05575 (NCTC12050_01109) - 1105153..1106328 (+) 1176 WP_014407506.1 hydroxymethylglutaryl-CoA synthase -
  DQL28_RS05580 (NCTC12050_01110) - 1106315..1107592 (+) 1278 WP_010922170.1 hydroxymethylglutaryl-CoA reductase, degradative -

Sequence

Protein


Download         Length: 409 a.a.        Molecular weight: 45021.46 Da        Isoelectric Point: 4.5775

>NTDB_id=1137085 DQL28_RS05555 WP_111676489.1 1101979..1103208(-) (clpX) [Streptococcus pyogenes strain NCTC12050]
MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDR
AKRALSVAVYNHYKRVSFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIQI
LTEPRNALVKQYQTLLSYDGVELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEG
KSKPVLETA

Nucleotide


Download         Length: 1230 bp        

>NTDB_id=1137085 DQL28_RS05555 WP_111676489.1 1101979..1103208(-) (clpX) [Streptococcus pyogenes strain NCTC12050]
ATGGCAGGAAGTAGAACTAACGATATTAAAGTATACTGTTCATTTTGTGGTAAAAGCCAGGATGACGTTAAAAAAATTAT
CGCAGGAAATAATGTTTTCATCTGCAATGAATGCGTAGCTTTATCACAAGAAATTATAAAAGAAGAATTGGCTGAAGAAG
TCCTTGCCGATTTGACAGAAGTTCCAAAACCAAAAGAGCTCCTTGATGTTTTAAATCAATATGTGGTTGGTCAAGATCGT
GCTAAACGTGCTTTATCAGTTGCTGTGTACAATCATTATAAGCGTGTCTCGTTTACAGAAAGTCGTGATGACGATGATGT
GGATTTACAAAAGTCCAACATTTTGATGATTGGACCAACAGGTTCAGGAAAAACCTTCTTAGCACAAACTCTGGCTAAAA
GCCTCAATGTACCATTTGCTATTGCAGATGCAACTTCTTTGACTGAAGCAGGGTATGTTGGAGAAGATGTGGAAAATATT
TTACTCAAACTGATTCAGGCTGCTGACTATAATGTCGAACGAGCAGAGCGTGGTATTATTTATGTTGATGAAATAGATAA
GATTGCTAAAAAAGGTGAGAACGTATCTATCACACGTGATGTATCTGGTGAAGGTGTACAGCAAGCCCTCCTTAAAATTA
TTGAAGGTACGGTAGCAAGTGTTCCCCCACAAGGTGGGCGGAAGCACCCTAATCAAGAAATGATCCAAATTGATACAAAA
AATATCTTGTTTATTGTTGGCGGGGCTTTTGATGGCATCGAGGAGATTGTTAAACAACGTTTAGGTGAAAAAGTTATTGG
TTTTGGTCAAAACAGCCGTAAAATTGATGACAATGCTTCTTATATGCAAGAAATTATTTCAGAAGATATTCAAAAGTTTG
GGCTTATTCCAGAATTTATTGGCCGCTTACCAGTTGTGGCAGCCCTTGAACAACTAAACACATCAGATTTGATTCAAATT
TTGACAGAACCAAGAAATGCCCTGGTCAAGCAATATCAGACCCTTCTTTCTTACGATGGCGTCGAATTGGCATTTGATAA
GGAAGCCTTAGAAGCCATTGCCAATAAAGCCATTGAACGTAAGACAGGAGCACGTGGTCTTCGTTCTATTATTGAAGAAA
CGATGTTAGACATTATGTTTGAAATTCCAAGCCAAGAAGATGTCACAAAAGTGCGTATCACCAAGGCTGCTGTCGAAGGC
AAGTCAAAACCCGTTTTAGAGACAGCTTAA

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(110-305)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(312-391)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

89.242

100

0.892
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.603

98.044

0.575

Multiple sequence alignment