Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   DQL35_RS08420 Genome accession   NZ_LS483325
Coordinates   1746197..1747519 (-) Length   440 a.a.
NCBI ID   WP_111678371.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC7022     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1741197..1752519
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL35_RS08410 (NCTC7022_01702) hpf 1744933..1745481 (-) 549 WP_012679953.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  DQL35_RS08415 (NCTC7022_01703) - 1745557..1746138 (-) 582 WP_111678856.1 ComF family protein -
  DQL35_RS08420 (NCTC7022_01704) comFA/cflA 1746197..1747519 (-) 1323 WP_111678371.1 DEAD/DEAH box helicase Machinery gene
  DQL35_RS08425 (NCTC7022_01705) - 1747575..1748216 (+) 642 WP_111678373.1 YigZ family protein -
  DQL35_RS08430 (NCTC7022_01706) cysK 1748337..1749263 (+) 927 WP_111678375.1 cysteine synthase A -
  DQL35_RS08435 (NCTC7022_01707) - 1749679..1750041 (-) 363 WP_012516140.1 S1 RNA-binding domain-containing protein -
  DQL35_RS08440 (NCTC7022_01708) - 1750041..1751441 (-) 1401 WP_111678377.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  DQL35_RS08445 (NCTC7022_01709) - 1751475..1752116 (-) 642 WP_021321066.1 response regulator -

Sequence

Protein


Download         Length: 440 a.a.        Molecular weight: 49937.11 Da        Isoelectric Point: 9.6000

>NTDB_id=1136585 DQL35_RS08420 WP_111678371.1 1746197..1747519(-) (comFA/cflA) [Streptococcus equi subsp. zooepidemicus strain NCTC7022]
MENIENYYGRLLPEGQCPKAVSVWACSLQSMIAKKGTLYCQRCSSLIEKAHQLPSGAYYCRACLVFGRNQSDRPLLYFPP
APFPKGHYLRWQGQLTTYQVAVSHQLTNHVKLKQDTLVHAVTGAGKTEMMYEAIAAVVDKGGWVCIASPRVDVCIELEKR
LSRDFSCQICLMHAESEAYHRSPIIIATTHQLMTFYHAFDLLIIDEVDAFPFVNNRQLNHAAHQAAKADAVTVYLTATST
RDLERKVKQKELVKLTLARRFHGKPLVVPKYQRLFSLLEAIHRGKLPRRLITLVKKQRATGYPLLIFFPLIELAEQCCQL
LQKYFPKETIAYASSQSSNRMAIIEQFRQGQITILISTTILERGVTFPTVDVFVLLANHRLYTSSSLIQISGRVGRSLER
PEGQVLFFHDGISKAMLKAVREIKDMNQKGYQNELSTLSQ

Nucleotide


Download         Length: 1323 bp        

>NTDB_id=1136585 DQL35_RS08420 WP_111678371.1 1746197..1747519(-) (comFA/cflA) [Streptococcus equi subsp. zooepidemicus strain NCTC7022]
ATGGAGAATATCGAAAATTACTATGGACGTCTTTTACCCGAAGGGCAATGCCCAAAGGCTGTTTCTGTCTGGGCTTGTAG
CTTACAAAGCATGATCGCTAAAAAAGGAACATTATACTGCCAACGCTGTAGCAGTTTAATTGAGAAAGCTCATCAGCTAC
CTAGCGGTGCTTACTACTGTAGAGCCTGTCTCGTTTTTGGTCGAAACCAATCTGATCGGCCCTTGCTCTATTTTCCACCG
GCTCCTTTTCCAAAGGGACATTATCTGAGGTGGCAAGGACAGCTCACAACATATCAGGTAGCTGTCTCTCATCAGCTTAC
TAACCATGTTAAGCTCAAGCAAGACACACTGGTTCATGCCGTTACCGGCGCTGGTAAAACAGAGATGATGTATGAAGCTA
TTGCAGCAGTTGTTGATAAGGGTGGCTGGGTCTGCATTGCTAGTCCACGAGTTGATGTCTGCATAGAGCTTGAAAAACGA
CTATCGCGGGACTTTTCCTGTCAAATCTGTCTTATGCATGCTGAGTCAGAGGCTTATCATAGAAGTCCCATAATCATTGC
CACAACACATCAATTGATGACCTTTTACCATGCTTTTGATCTGCTCATTATTGACGAAGTAGATGCCTTTCCTTTTGTCA
ACAATCGTCAATTAAACCATGCTGCTCATCAGGCTGCAAAAGCAGATGCAGTGACAGTATACCTAACAGCAACCTCTACA
AGAGACTTAGAGCGCAAGGTCAAGCAAAAAGAGCTTGTCAAATTGACATTAGCAAGAAGATTTCATGGCAAGCCCTTAGT
TGTCCCAAAGTATCAAAGATTATTCTCCCTTTTAGAGGCTATCCATCGCGGGAAATTGCCTAGAAGGTTAATCACCCTAG
TCAAAAAACAAAGGGCAACAGGCTATCCCCTCTTAATCTTTTTCCCACTTATTGAGCTGGCTGAGCAGTGCTGTCAGCTG
CTGCAAAAGTATTTTCCTAAGGAAACTATTGCTTATGCTTCCAGTCAGTCATCAAATCGAATGGCTATCATTGAGCAATT
TAGACAAGGACAAATCACTATACTCATATCAACAACCATTTTAGAAAGAGGTGTGACCTTTCCAACCGTAGATGTCTTTG
TCTTGTTAGCCAATCATCGCCTTTACACAAGCAGCAGTCTTATTCAGATTTCAGGTCGCGTCGGGCGTTCCTTGGAAAGG
CCTGAAGGACAGGTGCTGTTTTTTCATGATGGCATTAGCAAGGCCATGCTCAAGGCAGTGCGGGAGATAAAGGATATGAA
TCAAAAAGGGTATCAAAATGAACTGTCTACTCTGTCACAATAA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(287-396)

DEAD/DEAH box helicase (DEAD)

(111-244)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae R6

52.941

96.591

0.511
  comFA/cflA Streptococcus pneumoniae Rx1

52.941

96.591

0.511
  comFA/cflA Streptococcus pneumoniae D39

52.941

96.591

0.511
  comFA/cflA Streptococcus pneumoniae TIGR4

52.941

96.591

0.511
  comFA/cflA Streptococcus mitis SK321

52.941

96.591

0.511
  comFA/cflA Streptococcus mitis NCTC 12261

52.706

96.591

0.509
  comFA Lactococcus lactis subsp. cremoris KW2

47.704

89.091

0.425

Multiple sequence alignment