Detailed information NTG1136575

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: DQL35_RS05760
• Genome accession: NZ_LS483325
• Coordinates: 1185867..1187096 (-)
• Length: 409 a.a.
• NCBI ID: WP_111678172.1
• Uniprot ID: A0AAX2LJV2
• Organism: Streptococcus equi subsp. zooepidemicus strain NCTC7022
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1180867..1192096

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL35_RS05750 (NCTC7022_01150)	hupY	1181891..1184893 (-)	3003	WP_111678171.1	leucine-rich repeat adhesin HupY/LrrG	-
DQL35_RS05755 (NCTC7022_01151)	yihA	1185258..1185857 (-)	600	WP_012677890.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
DQL35_RS05760 (NCTC7022_01152)	clpX	1185867..1187096 (-)	1230	WP_111678172.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
DQL35_RS05765 (NCTC7022_01153)	-	1187132..1187302 (-)	171	WP_012515696.1	hypothetical protein	-
DQL35_RS05770 (NCTC7022_01154)	-	1187322..1187819 (-)	498	WP_111678173.1	dihydrofolate reductase	-
DQL35_RS05775 (NCTC7022_01155)	-	1187900..1188739 (-)	840	WP_043025902.1	thymidylate synthase	-
DQL35_RS05780 (NCTC7022_01156)	-	1188924..1190099 (+)	1176	WP_043025905.1	hydroxymethylglutaryl-CoA synthase	-
DQL35_RS05785 (NCTC7022_01157)	-	1190086..1191369 (+)	1284	WP_043030859.1	hydroxymethylglutaryl-CoA reductase, degradative	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 45183.75 Da
• Isoelectric Point: 4.5698

>NTDB_id=1136575 DQL35_RS05760 WP_111678172.1 1185867..1187096(-) (clpX) [Streptococcus equi subsp. zooepidemicus strain NCTC7022]
MAGNRSNDIKVHCSFCGKSQDEVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLDILNQYVIGQER
AKRALSVAVYNHYKRISFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKIIGFGQNSRKIDDNASYMQEIIAEDIQKFGLIPEFIGRLPVVAALEQLNTEDLIRI
LTEPRNALVKQYQALLSYDGVELEFEKGALEAIAGRAIERKTGARGLRSIIEETMLDIMFEVPSQEEVIKVRITKEAVEG
QSKPILEIA

Nucleotide

• Length: 1230 bp

>NTDB_id=1136575 DQL35_RS05760 WP_111678172.1 1185867..1187096(-) (clpX) [Streptococcus equi subsp. zooepidemicus strain NCTC7022]
ATGGCAGGAAATCGTAGTAACGATATTAAGGTTCATTGCTCGTTTTGCGGCAAGAGCCAAGACGAAGTGAAAAAAATTAT
TGCAGGCAATAACGTCTTTATTTGTAACGAATGTGTTGCCTTATCACAAGAAATCATCAAGGAAGAATTGGCAGAAGAGG
TTCTCGCTGATCTGACTGAGGTACCAAAGCCAAAAGAGCTCCTTGATATTTTAAACCAATACGTCATTGGTCAGGAGCGT
GCTAAGAGAGCCTTATCAGTTGCAGTTTATAATCATTACAAGAGGATTTCATTTACTGAGAGTCGTGACGATGATGATGT
GGATTTGCAAAAGTCAAACATTCTGATGATTGGACCAACAGGCTCAGGTAAGACCTTTTTAGCCCAGACTCTGGCTAAGA
GCCTTAATGTTCCATTTGCTATTGCTGATGCAACCTCTTTGACTGAAGCAGGTTATGTCGGAGAGGATGTGGAAAATATC
CTTCTGAAATTAATTCAAGCCGCTGATTACAATGTTGAACGTGCAGAGCGTGGCATTATTTATGTTGATGAAATTGATAA
AATCGCTAAAAAAGGTGAGAATGTCTCTATCACTCGTGATGTATCAGGAGAAGGTGTCCAACAAGCCTTGCTAAAAATTA
TTGAGGGAACGGTTGCTAGTGTTCCACCGCAAGGTGGTCGTAAGCACCCAAACCAAGAGATGATACAGATTGATACCAAA
AATATCTTGTTTATCGTCGGAGGCGCCTTTGATGGTATCGAAGAGATTGTCAAGCAGCGCTTGGGGGAAAAGATCATTGG
CTTTGGGCAAAATAGTCGAAAGATTGATGACAATGCCTCCTATATGCAGGAGATCATTGCTGAGGATATTCAAAAATTTG
GTCTGATTCCCGAATTTATTGGACGCTTGCCTGTTGTAGCAGCGCTTGAGCAGCTTAATACTGAGGATTTGATTCGTATT
TTAACAGAGCCTAGAAATGCTCTTGTGAAGCAATATCAAGCCTTATTGTCATATGATGGCGTAGAGCTTGAGTTTGAAAA
GGGTGCTCTGGAGGCTATTGCAGGCAGGGCTATTGAGCGCAAGACTGGTGCACGTGGTCTGAGGTCTATTATCGAAGAAA
CCATGCTGGATATCATGTTTGAGGTGCCAAGCCAAGAGGAAGTAATCAAGGTACGCATTACTAAGGAAGCTGTCGAAGGT
CAATCAAAGCCTATTTTAGAGATAGCCTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-389)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	88.753	100	0.888
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.853	98.044	0.577