Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrB   Type   Machinery gene
Locus tag   DQL79_RS00515 Genome accession   NZ_LS483324
Coordinates   92441..94069 (-) Length   542 a.a.
NCBI ID   WP_001836582.1    Uniprot ID   -
Organism   Staphylococcus aureus strain NCTC10344     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 87742..130745 92441..94069 within 0
SCCmec 92442..100721 92441..94069 flank -1627


Gene organization within MGE regions


Location: 87742..130745
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL79_RS00470 (NCTC10344_00089) - 87742..88416 (+) 675 WP_001105999.1 IS6-like element IS257 family transposase -
  DQL79_RS00475 (NCTC10344_00090) - 88681..89178 (-) 498 WP_000776433.1 GNAT family N-acetyltransferase -
  DQL79_RS00485 (NCTC10344_00091) - 89846..90256 (-) 411 WP_001836564.1 DUF2871 domain-containing protein -
  DQL79_RS00490 (NCTC10344_00092) - 90419..90640 (-) 222 WP_001836575.1 hypothetical protein -
  DQL79_RS00495 (NCTC10344_00093) - 90654..91157 (-) 504 WP_002494302.1 DUF1643 domain-containing protein -
  DQL79_RS00500 (NCTC10344_00094) - 91172..91483 (-) 312 WP_001836584.1 DUF960 family protein -
  DQL79_RS00510 (NCTC10344_00096) - 91570..91920 (-) 351 WP_001836581.1 SAUGI family uracil-DNA glycosylase inhibitor -
  DQL79_RS00515 (NCTC10344_00097) ccrB 92441..94069 (-) 1629 WP_001836582.1 cassette chromosome recombinase CcrB Machinery gene
  DQL79_RS00520 (NCTC10344_00098) ccrA 94091..95440 (-) 1350 WP_001836585.1 cassette chromosome recombinase CcrA Machinery gene
  DQL79_RS00525 (NCTC10344_00099) cch1 95674..97467 (-) 1794 WP_001836568.1 cassette chromosome replicative helicase -
  DQL79_RS00530 (NCTC10344_00100) ssb 97467..97760 (-) 294 WP_001836558.1 cassette chromosome ssDNA-binding protein -
  DQL79_RS00535 - 97994..99135 (+) 1142 WP_100228308.1 IS3 family transposase -
  DQL79_RS00540 (NCTC10344_00103) - 99207..100721 (-) 1515 WP_001836559.1 hypothetical protein -
  DQL79_RS00545 (NCTC10344_00104) - 100891..101940 (+) 1050 WP_001836576.1 ATP-binding protein -
  DQL79_RS00550 (NCTC10344_00105) - 101933..104146 (+) 2214 WP_001836580.1 S8 family peptidase -
  DQL79_RS00555 (NCTC10344_00106) pycC 104310..105581 (+) 1272 WP_000368660.1 Pycsar phage resistance system cytidylate cyclase PycC -
  DQL79_RS00560 (NCTC10344_00107) - 105587..106063 (+) 477 WP_001836567.1 Pycsar system effector family protein -
  DQL79_RS00565 (NCTC10344_00108) - 106102..107616 (+) 1515 WP_000190898.1 type I restriction-modification system subunit M -
  DQL79_RS00570 (NCTC10344_00109) - 107606..108838 (+) 1233 WP_000394003.1 restriction endonuclease subunit S -
  DQL79_RS00575 (NCTC10344_00110) - 108822..111950 (+) 3129 WP_001836570.1 type I restriction endonuclease subunit R -
  DQL79_RS00580 (NCTC10344_00111) - 112062..112769 (+) 708 WP_000667076.1 hypothetical protein -
  DQL79_RS00585 (NCTC10344_00112) - 112762..113265 (+) 504 WP_000575288.1 hypothetical protein -
  DQL79_RS00590 (NCTC10344_00113) - 113356..113814 (-) 459 Protein_109 tRNA-dihydrouridine synthase -
  DQL79_RS00595 - 113824..113925 (-) 102 WP_001791873.1 hypothetical protein -
  DQL79_RS00600 (NCTC10344_00114) - 114023..114778 (-) 756 WP_000355841.1 sulfite exporter TauE/SafE family protein -
  DQL79_RS00605 (NCTC10344_00115) cstR 114778..115038 (-) 261 WP_001105089.1 persulfide-sensing transcriptional repressor CstR -
  DQL79_RS00610 (NCTC10344_00116) cstA 115175..116242 (+) 1068 WP_001836572.1 persulfide response sulfurtransferase CstA -
  DQL79_RS00615 (NCTC10344_00117) cstB 116273..117607 (+) 1335 WP_000465473.1 persulfide dioxygenase-sulfurtransferase CstB -
  DQL79_RS00620 (NCTC10344_00118) sqr 117626..118819 (+) 1194 WP_001033011.1 type II sulfide:quinone oxidoreductase Sqr -
  DQL79_RS00635 (NCTC10344_00119) - 119485..120471 (-) 987 WP_000662023.1 tRNA dihydrouridine synthase -
  DQL79_RS00640 - 120780..120983 (+) 204 WP_000389759.1 DUF6007 family protein -
  DQL79_RS00645 (NCTC10344_00120) - 121032..121328 (+) 297 WP_000201644.1 TfoX/Sxy family protein -
  DQL79_RS00650 (NCTC10344_00121) - 121536..122138 (+) 603 WP_000908956.1 hypothetical protein -
  DQL79_RS00655 (NCTC10344_00122) - 122405..125557 (+) 3153 WP_001836569.1 DEAD/DEAH box helicase -
  DQL79_RS00660 (NCTC10344_00123) - 125614..126096 (+) 483 WP_000410567.1 hypothetical protein -
  DQL79_RS00665 (NCTC10344_00124) - 126302..127288 (+) 987 WP_000710555.1 phosphatidylinositol-specific phospholipase C -
  DQL79_RS00670 (NCTC10344_00125) - 127509..128279 (+) 771 WP_000977774.1 tandem-type lipoprotein -
  DQL79_RS00675 (NCTC10344_00126) - 128331..129101 (+) 771 WP_029693997.1 tandem-type lipoprotein -
  DQL79_RS00680 (NCTC10344_00127) - 129153..129923 (+) 771 WP_001805401.1 tandem-type lipoprotein -
  DQL79_RS00685 (NCTC10344_00128) - 129975..130745 (+) 771 WP_024273388.1 tandem-type lipoprotein -

Sequence

Protein


Download         Length: 542 a.a.        Molecular weight: 62622.75 Da        Isoelectric Point: 9.9149

>NTDB_id=1136505 DQL79_RS00515 WP_001836582.1 92441..94069(-) (ccrB) [Staphylococcus aureus strain NCTC10344]
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRMLKDAKEGNIDCVM
IYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVARVNQENKVDGAALHHDIAYKQQQYD
EVQTKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKSLFDAKQISKLLQHIFQDIKHMEKSRLK
ALYLSVIDRINIRKDDNHKKQFYVTLKLNNEVIKQVFNDTPLDEVHLSTSSLFLPQTLYLTI

Nucleotide


Download         Length: 1629 bp        

>NTDB_id=1136505 DQL79_RS00515 WP_001836582.1 92441..94069(-) (ccrB) [Staphylococcus aureus strain NCTC10344]
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTTTCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGATGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAGGTCAAAGATATATACGCTGATCGTGGTA
TTTCAGGTAAATCTATGAACAGACCTGAGCTCCAACGTATGTTGAAAGATGCAAAAGAAGGCAATATAGATTGTGTTATG
ATCTACAAAACAAACCGATTAGCTCGTAATACATCGGATCTTCTGAAAATCGTCGAAGATTTGCATAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCTTCTGGTAAACTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGACATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTGAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCTCAATGTGGCGCACCTATGGCAGCAAGCAATACAACGAATACACTTAAAGAT
GGGACCAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGCTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTCGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTTG
TAGCACGTGTTAATCAAGAAAATAAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAACCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGTCTT
TATTTGATGCCAAACAAATCAGTAAACTATTACAACACATCTTTCAAGATATTAAGCACATGGAAAAATCTCGACTCAAA
GCATTGTACCTATCAGTGATTGATCGTATTAATATTAGAAAAGATGACAATCATAAAAAACAGTTCTATGTCACACTCAA
ACTTAATAATGAAGTAATTAAACAGGTTTTCAATGATACTCCTCTCGACGAAGTGCATCTCAGCACTTCGTCTTTATTTT
TACCACAAACCCTATATCTTACTATTTAA

Domains

Predicted by InterproScan.

Recombinase (Recombinase)

(180-280)

Ogr/Delta-like zinc finger (Ogr_Delta)

(301-356)

Resolvase, N terminal domain (Resolvase)

(11-156)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrB Staphylococcus aureus N315

96.494

100

0.965

Multiple sequence alignment