Detailed information NTG1136370

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: DQL06_RS06095
• Genome accession: NZ_LS483321
• Coordinates: 1161342..1162571 (-)
• Length: 409 a.a.
• NCBI ID: WP_111689591.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC8314
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1156342..1167571

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL06_RS06075 (NCTC8314_01226)	rpiA	1156624..1157307 (-)	684	WP_009881270.1	ribose-5-phosphate isomerase RpiA	-
DQL06_RS06080 (NCTC8314_01227)	-	1157685..1159784 (+)	2100	WP_111689590.1	AAA family ATPase	-
DQL06_RS06085 (NCTC8314_01228)	-	1159842..1160585 (-)	744	WP_002984942.1	hypothetical protein	-
DQL06_RS06090 (NCTC8314_01229)	yihA	1160733..1161332 (-)	600	WP_002984945.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
DQL06_RS06095 (NCTC8314_01230)	clpX	1161342..1162571 (-)	1230	WP_111689591.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
DQL06_RS06105 (NCTC8314_01232)	-	1162891..1163388 (-)	498	WP_002984955.1	dihydrofolate reductase	-
DQL06_RS06110 (NCTC8314_01233)	-	1163468..1164307 (-)	840	WP_011017679.1	thymidylate synthase	-
DQL06_RS06115 (NCTC8314_01234)	-	1164516..1165691 (+)	1176	WP_111689592.1	hydroxymethylglutaryl-CoA synthase	-
DQL06_RS06120 (NCTC8314_01235)	-	1165678..1166955 (+)	1278	WP_111689593.1	hydroxymethylglutaryl-CoA reductase, degradative	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 45003.49 Da
• Isoelectric Point: 4.5775

>NTDB_id=1136370 DQL06_RS06095 WP_111689591.1 1161342..1162571(-) (clpX) [Streptococcus pyogenes strain NCTC8314]
MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDR
AKRALSVAVYNHYKRVSFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIQI
LIEPRNALVKQYQALLSYDGVELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEG
KSKPVLETA

Nucleotide

• Length: 1230 bp

>NTDB_id=1136370 DQL06_RS06095 WP_111689591.1 1161342..1162571(-) (clpX) [Streptococcus pyogenes strain NCTC8314]
ATGGCAGGAAGTAGAACTAACGATATTAAAGTATACTGTTCATTTTGTGGTAAAAGCCAGGATGACGTTAAAAAAATTAT
CGCAGGAAATAATGTTTTCATCTGCAATGAATGCGTAGCTTTATCACAAGAAATTATAAAAGAAGAATTGGCTGAAGAAG
TCCTTGCCGATTTGACAGAAGTTCCAAAACCAAAAGAGCTCCTTGATGTTTTAAATCAATATGTGGTTGGTCAAGATCGT
GCTAAACGTGCTTTATCAGTTGCTGTGTACAATCATTATAAGCGTGTCTCGTTTACAGAAAGTCGTGATGACGATGATGT
GGATTTACAAAAGTCCAACATTTTGATGATTGGACCAACAGGTTCAGGAAAAACCTTCTTAGCACAAACTCTGGCTAAAA
GCCTCAATGTACCATTTGCTATTGCAGATGCAACTTCTTTGACTGAAGCAGGGTATGTTGGAGAAGATGTGGAAAATATT
TTACTCAAACTGATTCAGGCTGCTGACTATAATGTCGAACGAGCAGAGCGTGGTATTATTTATGTTGATGAAATAGATAA
GATTGCTAAAAAAGGTGAGAACGTATCTATCACACGTGATGTATCTGGTGAAGGTGTACAGCAAGCCCTTCTTAAAATTA
TTGAAGGTACGGTAGCAAGTGTTCCCCCACAAGGTGGGCGGAAGCACCCTAATCAAGAAATGATCCAAATTGATACAAAA
AATATCTTGTTTATTGTTGGCGGGGCTTTTGATGGCATCGAGGAGATTGTTAAACAACGTTTAGGTGAAAAAGTTATTGG
TTTTGGTCAAAACAGCCGTAAAATTGATGACAATGCTTCTTATATGCAAGAAATTATTTCAGAAGATATTCAAAAGTTTG
GGCTTATTCCAGAATTTATTGGCCGCTTACCAGTTGTGGCAGCCCTTGAACAACTAAACACATCAGATTTGATTCAAATT
TTGATAGAACCAAGAAATGCCCTGGTCAAGCAATATCAGGCTCTTCTTTCTTACGATGGCGTCGAATTGGCATTTGATAA
GGAAGCCTTAGAAGCCATTGCCAATAAAGCCATTGAACGTAAGACAGGAGCACGTGGTCTTCGTTCTATTATCGAAGAAA
CGATGTTAGACATCATGTTTGAAATTCCAAGCCAAGAAGATGTCACAAAAGTGCGTATCACCAAGGCTGCTGTCGAAGGC
AAGTCAAAACCCGTTTTAGAGACCGCTTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-391)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	88.753	100	0.888
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.354	98.044	0.572