Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   DQM44_RS04405 Genome accession   NZ_LS483318
Coordinates   836124..837353 (+) Length   409 a.a.
NCBI ID   WP_022554539.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. equisimilis strain NCTC5370     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 831124..842353
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM44_RS04375 (NCTC5370_00905) - 831274..831558 (-) 285 WP_022554535.1 hypothetical protein -
  DQM44_RS04380 (NCTC5370_00906) - 831746..833023 (-) 1278 WP_065354824.1 hydroxymethylglutaryl-CoA reductase, degradative -
  DQM44_RS04385 (NCTC5370_00907) - 833004..834185 (-) 1182 WP_022554538.1 hydroxymethylglutaryl-CoA synthase -
  DQM44_RS04390 (NCTC5370_00908) - 834403..835242 (+) 840 WP_003054196.1 thymidylate synthase -
  DQM44_RS04395 (NCTC5370_00909) - 835323..835820 (+) 498 WP_003054187.1 dihydrofolate reductase -
  DQM44_RS04400 (NCTC5370_00910) - 835840..836010 (+) 171 WP_003054200.1 hypothetical protein -
  DQM44_RS04405 (NCTC5370_00911) clpX 836124..837353 (+) 1230 WP_022554539.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  DQM44_RS04410 (NCTC5370_00912) yihA 837363..837962 (+) 600 WP_003061604.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  DQM44_RS04415 (NCTC5370_00913) - 838106..838849 (+) 744 WP_022554540.1 hypothetical protein -
  DQM44_RS04420 (NCTC5370_00914) clpC 838906..841005 (-) 2100 WP_015057518.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  DQM44_RS04425 - 841503..841910 (-) 408 Protein_826 IS30 family transposase -
  DQM44_RS10605 - 841904..842122 (+) 219 Protein_827 IS30 family transposase -

Sequence

Protein


Download         Length: 409 a.a.        Molecular weight: 45034.46 Da        Isoelectric Point: 4.5866

>NTDB_id=1136202 DQM44_RS04405 WP_022554539.1 836124..837353(+) (clpX) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC5370]
MAGNRTNDIKVYCSFCGKSQDEVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLEVLNQYVVGQDR
AKRALSVAVYNHYKRVSFTESRDDEDVELQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEDIVKQRLGEKVIGFGQNSRKIDDNASYMQEISSEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIQI
LTEPRNALVKQYQALLSYDGVELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEG
KSKPVLETA

Nucleotide


Download         Length: 1230 bp        

>NTDB_id=1136202 DQM44_RS04405 WP_022554539.1 836124..837353(+) (clpX) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC5370]
ATGGCAGGAAATCGTACAAACGATATTAAAGTATATTGCTCATTTTGTGGTAAGAGCCAAGACGAAGTCAAAAAAATTAT
TGCAGGGAATAATGTTTTTATCTGTAATGAATGTGTGGCTTTGTCACAAGAAATTATTAAAGAAGAGTTGGCAGAAGAAG
TGTTAGCTGACCTAACAGAAGTTCCAAAACCAAAAGAACTCCTTGAGGTTTTAAACCAGTATGTTGTTGGTCAAGATCGT
GCCAAACGTGCTTTATCAGTAGCTGTTTACAATCATTACAAACGCGTGTCATTCACGGAAAGTCGTGATGATGAAGATGT
TGAATTGCAAAAATCAAACATTTTAATGATTGGTCCAACAGGTTCAGGAAAGACTTTTCTCGCTCAAACCTTAGCTAAGA
GCTTAAATGTTCCTTTTGCGATTGCTGATGCAACCTCACTGACTGAAGCAGGGTATGTTGGAGAAGATGTGGAAAATATT
CTTCTCAAGCTTATCCAAGCAGCTGATTATAATGTGGAACGAGCAGAGCGTGGTATCATCTATGTCGATGAAATTGATAA
GATTGCTAAAAAAGGTGAAAATGTGTCCATCACACGTGATGTTTCTGGTGAGGGAGTTCAACAGGCCTTGCTAAAAATCA
TTGAAGGAACGGTTGCTAGTGTTCCTCCTCAAGGCGGTCGTAAGCATCCAAATCAGGAAATGATTCAAATTGATACCAAG
AATATCTTGTTTATTGTTGGGGGAGCCTTTGATGGCATTGAAGACATTGTCAAACAACGTTTAGGAGAAAAAGTCATTGG
TTTTGGTCAAAACAGCCGAAAAATCGATGACAATGCTTCTTATATGCAAGAGATTAGTTCAGAAGATATCCAAAAATTTG
GTCTTATCCCAGAGTTTATTGGACGCTTGCCAGTCGTAGCTGCTCTTGAACAACTAAACACATCAGATTTGATTCAAATT
TTGACGGAACCAAGAAATGCCCTAGTCAAGCAATATCAGGCTCTTCTTTCTTACGATGGTGTCGAATTGGCATTTGATAA
GGAAGCCTTAGAAGCCATTGCAAATAAAGCCATTGAGCGTAAGACAGGCGCGCGTGGTCTTCGTTCTATTATCGAAGAAA
CGATGTTAGACATTATGTTTGAAATTCCAAGCCAAGAAGATGTCACAAAAGTGCGTATCACCAAGGCTGCTGTCGAAGGC
AAGTCAAAACCCGTTTTAGAGACAGCTTAA

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

AAA domain (Cdc48 subfamily) (AAA_2)

(110-305)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(312-391)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

89.242

100

0.892
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.853

98.044

0.577

Multiple sequence alignment