Detailed information NTG1136174

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: DQL75_RS13995
• Genome accession: NZ_LS483317
• Coordinates: 2711744..2712631 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain NCTC5663
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2706744..2717631

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL75_RS13960	-	2706752..2706844 (+)	93	WP_010956583.1	hypothetical protein	-
DQL75_RS13965 (NCTC5663_02624)	-	2706952..2707449 (-)	498	WP_001065267.1	glutathione peroxidase	-
DQL75_RS13970	-	2707459..2707719 (-)	261	WP_078056482.1	hypothetical protein	-
DQL75_RS13980	-	2708101..2708214 (-)	114	WP_072468803.1	hypothetical protein	-
DQL75_RS13985 (NCTC5663_02625)	-	2708884..2710884 (-)	2001	WP_111762748.1	ABC transporter permease	-
DQL75_RS13990 (NCTC5663_02626)	-	2710881..2711636 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
DQL75_RS13995 (NCTC5663_02627)	braS	2711744..2712631 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
DQL75_RS14000 (NCTC5663_02628)	braR	2712642..2713307 (-)	666	WP_000697879.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
DQL75_RS14005 (NCTC5663_02629)	-	2713333..2713533 (-)	201	WP_000604725.1	hypothetical protein	-
DQL75_RS14010 (NCTC5663_02630)	-	2713731..2715155 (+)	1425	WP_111762749.1	alkaline phosphatase	-
DQL75_RS14760 (NCTC5663_02631)	-	2715214..2715315 (-)	102	WP_000731976.1	SE2200 family small protein	-
DQL75_RS14020 (NCTC5663_02632)	-	2715437..2715892 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
DQL75_RS14025 (NCTC5663_02633)	-	2716137..2716898 (-)	762	WP_000323448.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=1136174 DQL75_RS13995 WP_000143420.1 2711744..2712631(-) (braS) [Staphylococcus aureus strain NCTC5663]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1136174 DQL75_RS13995 WP_000143420.1 2711744..2712631(-) (braS) [Staphylococcus aureus strain NCTC5663]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCAGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993