Detailed information NTG1136145

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: DQL75_RS05310
• Genome accession: NZ_LS483317
• Coordinates: 1025459..1026445 (+)
• Length: 328 a.a.
• NCBI ID: WP_111762128.1
• Uniprot ID: A0A380DZQ3
• Organism: Staphylococcus aureus strain NCTC5663
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 1020459..1031445

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL75_RS05285 (NCTC5663_01003)	opp4B	1020671..1021633 (+)	963	WP_000593417.1	oligopeptide ABC transporter permease	-
DQL75_RS05290 (NCTC5663_01004)	opp4C	1021645..1022526 (+)	882	WP_001180264.1	oligopeptide ABC transporter permease	-
DQL75_RS05295 (NCTC5663_01005)	trpS	1022568..1023557 (-)	990	WP_111762126.1	tryptophan--tRNA ligase	-
DQL75_RS05300 (NCTC5663_01006)	spxA	1023852..1024247 (+)	396	WP_000258003.1	transcriptional regulator SpxA	-
DQL75_RS05305 (NCTC5663_01007)	mecA	1024618..1025337 (+)	720	WP_111762127.1	adaptor protein MecA	-
DQL75_RS05310 (NCTC5663_01008)	coiA	1025459..1026445 (+)	987	WP_111762128.1	competence protein CoiA	Machinery gene
DQL75_RS05315 (NCTC5663_01009)	pepF	1026493..1028301 (+)	1809	WP_111762129.1	oligoendopeptidase F	-
DQL75_RS05320 (NCTC5663_01012)	yjbH	1028761..1029567 (-)	807	WP_000896697.1	protease adaptor protein YjbH	-
DQL75_RS05325 (NCTC5663_01013)	-	1029590..1029955 (-)	366	WP_000214067.1	truncated hemoglobin YjbI	-
DQL75_RS05330 (NCTC5663_01014)	-	1030059..1030652 (-)	594	WP_000224622.1	CYTH domain-containing protein	-
DQL75_RS05335 (NCTC5663_01015)	-	1030838..1031185 (+)	348	WP_001242107.1	hypothetical protein	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38703.19 Da
• Isoelectric Point: 9.5827

>NTDB_id=1136145 DQL75_RS05310 WP_111762128.1 1025459..1026445(+) (coiA) [Staphylococcus aureus strain NCTC5663]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNESIKHYKSKLILAQMIQQQGCKV
EIEPFLKKIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFQSMFINPITRKL
HTFNLEKKQIMMFQQIQYIGGHKYVAEKGNAKISELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLH
LTDQEVVHNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSNLESDNLNYFKLKKFIVALESKTAIIEKLINNYLNISSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=1136145 DQL75_RS05310 WP_111762128.1 1025459..1026445(+) (coiA) [Staphylococcus aureus strain NCTC5663]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGCGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCGGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAATCGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAAAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCAAAGTATGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAGATACAATATATAGGCGGGCACAAATATGTCGCTGA
AAAAGGGAATGCCAAAATTAGTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAATTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAGTTGCAT
TTAACTGATCAAGAAGTAGTGCACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAATTTAGAAAGTGACAATCTTAATTATTTTAAACTGAAAA
AGTTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTAGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-306)

3D structure

• AlphaFold DB: A0A380DZQ3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	96.037	100	0.96
coiA	Staphylococcus aureus MW2	96.037	100	0.96