Detailed information NTG1136070

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: DQL11_RS05770
• Genome accession: NZ_LS483315
• Coordinates: 1112902..1114131 (-)
• Length: 409 a.a.
• NCBI ID: WP_111704688.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC12059
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1107902..1119131

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL11_RS05750 (NCTC12059_01152)	rpiA	1108184..1108867 (-)	684	WP_021733827.1	ribose-5-phosphate isomerase RpiA	-
DQL11_RS05755 (NCTC12059_01153)	-	1109245..1111344 (+)	2100	WP_021733828.1	AAA family ATPase	-
DQL11_RS05760 (NCTC12059_01154)	-	1111402..1112145 (-)	744	WP_002984942.1	hypothetical protein	-
DQL11_RS05765 (NCTC12059_01155)	yihA	1112293..1112892 (-)	600	WP_011184414.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
DQL11_RS05770 (NCTC12059_01156)	clpX	1112902..1114131 (-)	1230	WP_111704688.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
DQL11_RS05780 (NCTC12059_01158)	-	1114451..1114948 (-)	498	WP_002984955.1	dihydrofolate reductase	-
DQL11_RS05785 (NCTC12059_01159)	-	1115028..1115867 (-)	840	WP_010922172.1	thymidylate synthase	-
DQL11_RS05790 (NCTC12059_01160)	-	1116076..1117251 (+)	1176	WP_093974767.1	hydroxymethylglutaryl-CoA synthase	-
DQL11_RS05795 (NCTC12059_01161)	-	1117238..1118515 (+)	1278	WP_010922170.1	hydroxymethylglutaryl-CoA reductase, degradative	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 44972.39 Da
• Isoelectric Point: 4.5771

>NTDB_id=1136070 DQL11_RS05770 WP_111704688.1 1112902..1114131(-) (clpX) [Streptococcus pyogenes strain NCTC12059]
MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDR
AKRALSVAVYNHYKRVSFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSHKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIQI
LTEPRNALVKQYQALLSYDGVELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEG
KSKPVLETA

Nucleotide

• Length: 1230 bp

>NTDB_id=1136070 DQL11_RS05770 WP_111704688.1 1112902..1114131(-) (clpX) [Streptococcus pyogenes strain NCTC12059]
ATGGCAGGAAGTAGAACTAACGATATTAAAGTATACTGTTCATTTTGTGGTAAAAGCCAGGATGACGTTAAAAAAATTAT
CGCAGGAAATAATGTTTTCATCTGCAATGAATGCGTAGCTTTATCACAAGAAATTATAAAAGAAGAATTGGCTGAAGAAG
TCCTTGCCGATTTGACAGAAGTTCCAAAACCAAAAGAGCTCCTTGATGTTTTAAATCAATATGTGGTTGGTCAAGATCGT
GCTAAACGTGCTTTATCAGTTGCTGTGTACAATCATTATAAGCGTGTCTCGTTTACAGAAAGTCGTGATGACGATGATGT
GGATTTACAAAAGTCCAACATTTTGATGATTGGACCAACAGGTTCAGGAAAAACCTTCTTAGCACAAACTCTGGCTAAAA
GCCTCAATGTACCATTTGCTATTGCAGATGCAACTTCTTTGACTGAAGCAGGGTATGTTGGAGAAGATGTGGAAAATATT
TTACTCAAACTGATTCAGGCTGCTGACTATAATGTCGAACGAGCAGAGCGTGGTATTATTTATGTTGATGAAATAGATAA
GATTGCTAAAAAAGGTGAGAACGTATCTATCACACGTGATGTATCTGGTGAAGGTGTACAGCAAGCCCTTCTTAAAATTA
TTGAAGGTACGGTAGCAAGTGTTCCCCCACAAGGTGGGCGGAAGCACCCTAATCAAGAAATGATCCAAATTGATACAAAA
AATATCTTGTTTATTGTTGGCGGGGCTTTTGATGGCATCGAGGAGATTGTTAAACAACGTTTAGGTGAAAAAGTTATTGG
TTTTGGTCAAAACAGCCATAAAATTGATGACAATGCTTCTTATATGCAAGAAATTATTTCAGAAGATATTCAAAAGTTTG
GGCTTATTCCAGAATTTATTGGCCGCTTACCAGTTGTGGCAGCCCTTGAACAACTAAACACATCAGATTTGATTCAAATT
TTGACAGAACCAAGAAATGCCCTGGTCAAGCAATATCAGGCTCTTCTTTCTTACGATGGCGTCGAATTGGCATTTGATAA
GGAAGCCTTAGAAGCCATTGCCAATAAAGCCATTGAACGTAAGACAGGAGCACGTGGTCTTCGTTCTATTATCGAAGAAA
CGATGTTAGACATTATGTTTGAAATTCCAAGCCAAGAAGATGTCACAAAAGTGCGTATCACCAAGGCTGCTGTCGAAGGC
AAGTCAAAACCCGTTTTAGAGACAGCTTAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-391)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	88.998	100	0.89
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.603	98.044	0.575