Detailed information NTG1135614

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: DQL80_RS09700
• Genome accession: NZ_LS483302
• Coordinates: 1922882..1923925 (-)
• Length: 347 a.a.
• NCBI ID: WP_111680449.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain NCTC8726
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1917882..1928925

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL80_RS09670 (NCTC8726_01831)	-	1918302..1919558 (-)	1257	WP_001793983.1	aminopeptidase	-
DQL80_RS09675 (NCTC8726_01832)	-	1919561..1919761 (-)	201	WP_000180460.1	DUF1128 family protein	-
DQL80_RS09680 (NCTC8726_01833)	-	1919908..1920372 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
DQL80_RS09685 (NCTC8726_01834)	-	1920379..1920654 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
DQL80_RS09690 (NCTC8726_01835)	-	1920933..1922150 (+)	1218	WP_111680448.1	YihY/virulence factor BrkB family protein	-
DQL80_RS09695 (NCTC8726_01836)	vraR	1922263..1922892 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
DQL80_RS09700 (NCTC8726_01837)	vraS	1922882..1923925 (-)	1044	WP_111680449.1	sensor histidine kinase	Regulator
DQL80_RS09705 (NCTC8726_01838)	liaF	1923922..1924623 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
DQL80_RS09710 (NCTC8726_01839)	-	1924638..1925024 (-)	387	WP_111680450.1	hypothetical protein	-
DQL80_RS09715 (NCTC8726_01840)	map	1925241..1925999 (-)	759	WP_111680451.1	type I methionyl aminopeptidase	-
DQL80_RS09725 (NCTC8726_01841)	-	1926474..1927460 (+)	987	WP_000999713.1	FUSC family protein	-
DQL80_RS09730 (NCTC8726_01842)	-	1927636..1928052 (-)	417	WP_111680727.1	hypothetical protein	-
DQL80_RS09735	-	1928081..1928190 (-)	110	Protein_1808	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40060.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1135614 DQL80_RS09700 WP_111680449.1 1922882..1923925(-) (vraS) [Staphylococcus aureus strain NCTC8726]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERSLEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1135614 DQL80_RS09700 WP_111680449.1 1922882..1923925(-) (vraS) [Staphylococcus aureus strain NCTC8726]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTACCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTCGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGATCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	99.712	100	0.997