Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   DQL80_RS08005 Genome accession   NZ_LS483302
Coordinates   1617777..1618463 (-) Length   228 a.a.
NCBI ID   WP_072468915.1    Uniprot ID   A0A5F0HFN7
Organism   Staphylococcus aureus strain NCTC8726     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1612777..1623463
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL80_RS07985 (NCTC8726_01516) rpsT 1613691..1613942 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  DQL80_RS07990 (NCTC8726_01517) holA 1613987..1614961 (-) 975 WP_111680361.1 DNA polymerase III subunit delta -
  DQL80_RS07995 (NCTC8726_01518) comEC 1615018..1617219 (-) 2202 WP_172452443.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  DQL80_RS08000 (NCTC8726_01519) - 1617224..1617685 (-) 462 WP_000439693.1 ComE operon protein 2 -
  DQL80_RS08005 (NCTC8726_01520) comEA 1617777..1618463 (-) 687 WP_072468915.1 ComEA family DNA-binding protein Machinery gene
  DQL80_RS08010 (NCTC8726_01521) - 1618503..1619219 (-) 717 WP_000084840.1 class I SAM-dependent DNA methyltransferase -
  DQL80_RS08015 (NCTC8726_01522) rsfS 1619222..1619575 (-) 354 WP_001088020.1 ribosome silencing factor -
  DQL80_RS08020 (NCTC8726_01523) yqeK 1619576..1620160 (-) 585 WP_111680363.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  DQL80_RS08025 (NCTC8726_01524) nadD 1620150..1620719 (-) 570 WP_000725164.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  DQL80_RS08030 (NCTC8726_01525) yhbY 1620722..1621012 (-) 291 WP_000955234.1 ribosome assembly RNA-binding protein YhbY -
  DQL80_RS08035 (NCTC8726_01526) aroE 1621016..1621822 (-) 807 WP_111680364.1 shikimate dehydrogenase -
  DQL80_RS08040 (NCTC8726_01527) yqeH 1621836..1622936 (-) 1101 WP_111680365.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25812.41 Da        Isoelectric Point: 9.3305

>NTDB_id=1135605 DQL80_RS08005 WP_072468915.1 1617777..1618463(-) (comEA) [Staphylococcus aureus strain NCTC8726]
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRDFENKDTALKQSTSENSSLSKLEDVQAKDGDNSK
NKGPVYVDIKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQFGENSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=1135605 DQL80_RS08005 WP_072468915.1 1617777..1618463(-) (comEA) [Staphylococcus aureus strain NCTC8726]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAGATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAATTAGAAGATGTCCAGGCCAAAGATGGAGATAATTCCAAA
AATAAAGGTCCTGTATATGTCGATATAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGATGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATTCCTCATAAAGGACAAAAGAATGTTGAACCACAATTTGGAGAAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5F0HFN7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

96.476

99.561

0.961
  comEA Staphylococcus aureus N315

96.476

99.561

0.961

Multiple sequence alignment