Detailed information NTG1135563

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: DQL88_RS08760
• Genome accession: NZ_LS483301
• Coordinates: 1707950..1710151 (-)
• Length: 733 a.a.
• NCBI ID: WP_001566051.1
• Uniprot ID: A0A266CU80
• Organism: Staphylococcus aureus strain NCTC13394
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1702950..1715151

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL88_RS08745 (NCTC13394_01626)	lepA	1704454..1706277 (-)	1824	WP_000368341.1	translation elongation factor 4	-
DQL88_RS08750 (NCTC13394_01627)	rpsT	1706623..1706874 (+)	252	WP_001274017.1	30S ribosomal protein S20	-
DQL88_RS08755 (NCTC13394_01628)	holA	1706919..1707893 (-)	975	WP_001282562.1	DNA polymerase III subunit delta	-
DQL88_RS08760 (NCTC13394_01629)	comEC	1707950..1710151 (-)	2202	WP_001566051.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
DQL88_RS08765 (NCTC13394_01630)	-	1710156..1710617 (-)	462	WP_000439693.1	ComE operon protein 2	-
DQL88_RS08770 (NCTC13394_01631)	comEA	1710709..1711395 (-)	687	WP_001792568.1	ComEA family DNA-binding protein	Machinery gene
DQL88_RS08775 (NCTC13394_01632)	-	1711435..1712151 (-)	717	WP_000084829.1	class I SAM-dependent DNA methyltransferase	-
DQL88_RS08780 (NCTC13394_01633)	rsfS	1712154..1712507 (-)	354	WP_001088022.1	ribosome silencing factor	-
DQL88_RS08785 (NCTC13394_01634)	yqeK	1712508..1713092 (-)	585	WP_001019324.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
DQL88_RS08790 (NCTC13394_01635)	nadD	1713082..1713651 (-)	570	WP_000725162.1	nicotinate (nicotinamide) nucleotide adenylyltransferase	-
DQL88_RS08795 (NCTC13394_01636)	yhbY	1713654..1713944 (-)	291	WP_000955231.1	ribosome assembly RNA-binding protein YhbY	-
DQL88_RS08800 (NCTC13394_01637)	aroE	1713948..1714754 (-)	807	WP_000666761.1	shikimate dehydrogenase	-

Sequence

Protein

• Length: 733 a.a.
• Molecular weight: 84839.89 Da
• Isoelectric Point: 10.0277

>NTDB_id=1135563 DQL88_RS08760 WP_001566051.1 1707950..1710151(-) (comEC) [Staphylococcus aureus strain NCTC13394]
MLFVALSMIVGVLWNSSKVLSTFLFILLLYITYRKNKIVYAPISLFLIIFSAWYLHYSQQAIFNYINYIERNSQFNERAQ
VIQIQRQGSDTYKGRLSLKNEIYPFFLTDKKNFDLKKIESRNCIVKGQFKVNDNKFVTLKLQSIVVQSCLESNRSNLIEK
HKQFIMNRIYDSGIKFPDRIMALITGDVKEVNEQFKERVKEIGIYHLLAVSGSHIAAIVFLIYQPLKRLNLPLFVIKGIT
IIVLALFAQYTNYAPSAVRAIIMTTLVLVITKQIKIKSIQLLAFAFIIMFILNPLVVYDIGFQFSFIISFFIMLLFPFLQ
QLSKLQSLFIITFIAQLASFIVAIPSFHQLQWVGFLSNLIFVPYYSIILFPLSILFFITSHFIVGLTPLNYLVDLSFNFH
DWLLDLFTRIKQSHFSVPKFNDWIFIVFIISVYYIFWLLAKRKYILVTFWTIIILTLLITFPTNSHHKITMLNVGQGDSI
LYEGGKNQNVLIDTGGKVIDDTKQPSYSISKYHILPTLNERGINELEYLILTHPHNDHIGEVEYIISHIKIKHIVIYNKG
YSSNTLMLLSKLSHKYNIKLMDVRQVSSFKLGDSSFLFFDSFIPNSRDKNEYSIITMITYQNKKVLLMGDASKNNESLLL
KKYNLPEIDILKVGHHGSKTSSSKEFIEMIKPKISLISSGKNNMYHLPNIEVVKRLQRIRSRIYNSQQNGQVTIDLDDNL
KVDSSSYGNASGL

Nucleotide

• Length: 2202 bp

>NTDB_id=1135563 DQL88_RS08760 WP_001566051.1 1707950..1710151(-) (comEC) [Staphylococcus aureus strain NCTC13394]
TTGCTGTTTGTCGCGTTATCAATGATTGTAGGAGTGCTTTGGAATTCTAGCAAAGTGCTCTCTACATTTCTTTTCATTTT
ACTTTTGTATATTACTTATCGTAAAAATAAAATCGTTTATGCCCCTATTTCTCTCTTTTTAATCATTTTCTCCGCATGGT
ATTTACATTATTCACAACAAGCAATATTTAATTATATCAATTATATTGAACGTAATTCTCAGTTTAATGAGCGTGCTCAA
GTAATCCAAATTCAACGTCAAGGTAGTGACACATATAAAGGTAGGTTGAGTTTAAAAAATGAAATATATCCTTTCTTTTT
AACAGATAAAAAGAATTTTGATTTAAAGAAAATTGAAAGTCGTAATTGTATTGTTAAAGGACAATTCAAAGTTAATGACA
ATAAGTTTGTAACTCTTAAATTACAAAGTATAGTTGTACAAAGCTGCCTAGAATCGAACCGGTCTAATTTAATTGAGAAA
CATAAACAGTTTATAATGAATCGAATTTATGATTCGGGTATTAAGTTTCCGGATCGTATTATGGCATTGATTACTGGTGA
CGTAAAAGAAGTTAATGAGCAATTTAAGGAACGTGTTAAAGAGATAGGTATATATCATTTGCTGGCAGTTAGTGGCTCGC
ATATAGCTGCAATTGTATTTTTAATTTACCAACCTTTAAAACGATTAAATTTACCTTTATTTGTCATTAAAGGAATTACA
ATCATTGTATTAGCTTTATTTGCTCAATACACAAATTATGCACCTAGTGCTGTAAGAGCTATAATAATGACAACTCTTGT
ACTGGTTATTACTAAGCAAATTAAAATAAAGAGTATTCAGCTATTAGCATTTGCATTTATAATTATGTTTATTTTAAATC
CACTAGTTGTTTATGATATTGGATTTCAATTTTCATTCATCATTTCATTTTTTATTATGCTACTTTTTCCTTTTTTACAG
CAATTGTCAAAGTTACAATCATTATTCATAATTACGTTTATTGCACAATTAGCTTCATTTATCGTTGCCATTCCAAGCTT
TCATCAACTTCAATGGGTGGGATTTTTATCTAATTTGATTTTTGTACCGTACTATTCGATTATATTGTTTCCGCTATCTA
TTTTATTCTTTATTACAAGTCATTTTATTGTGGGATTAACGCCGCTAAATTACTTGGTTGACCTAAGTTTTAATTTTCAT
GACTGGTTACTAGACCTATTCACAAGAATCAAGCAATCACATTTTTCTGTTCCCAAGTTTAATGATTGGATATTTATAGT
ATTTATAATTTCTGTTTATTACATATTTTGGTTATTGGCTAAACGTAAATATATATTGGTTACGTTTTGGACTATAATTA
TTCTGACATTATTAATAACGTTTCCAACAAATTCACATCACAAAATTACAATGTTAAATGTGGGGCAGGGAGACAGTATT
TTATATGAAGGCGGTAAGAACCAAAATGTCTTGATTGATACAGGTGGGAAAGTGATTGATGATACTAAACAACCTAGTTA
TTCAATTTCTAAATATCATATTTTACCAACGCTAAATGAAAGAGGGATAAATGAATTAGAGTATCTAATTTTAACACATC
CACACAATGACCATATTGGTGAAGTGGAATATATTATTAGTCATATTAAAATTAAACATATAGTGATATACAATAAGGGA
TATAGTAGTAATACATTGATGTTATTATCGAAATTAAGCCATAAGTACAACATTAAACTTATGGATGTAAGACAAGTTAG
TAGTTTTAAACTTGGAGATAGTAGTTTTCTATTTTTTGATAGTTTTATTCCAAATAGCCGAGATAAAAATGAGTATTCGA
TTATTACTATGATTACATATCAAAATAAAAAAGTTTTATTAATGGGCGATGCTAGTAAAAATAATGAATCTTTACTACTA
AAAAAATATAACTTGCCGGAGATTGATATTTTAAAAGTAGGACATCATGGGAGCAAGACAAGTAGTTCTAAAGAATTTAT
AGAGATGATTAAGCCTAAAATAAGTTTGATTTCTTCTGGGAAGAACAATATGTATCATCTTCCTAATATAGAAGTTGTTA
AACGATTGCAAAGGATTCGCAGTCGCATTTACAATAGTCAACAAAACGGTCAAGTTACAATTGACTTAGATGATAATTTA
AAAGTTGATTCAAGCTCTTATGGAAATGCAAGTGGTTTATAG

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (474-679)

• Competence protein (Competence) (183-441)

3D structure

• AlphaFold DB: A0A266CU80

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Staphylococcus aureus N315	98.499	100	0.985
comEC	Staphylococcus aureus MW2	98.09	100	0.981