Detailed information NTG0113389

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: NI25_RS17000
• Genome accession: NZ_CP009754
• Coordinates: 3884368..3885492 (+)
• Length: 374 a.a.
• NCBI ID: WP_030404779.1
• Uniprot ID: A0A6B3QRH4
• Organism: Streptomyces sp. CCM_MD2014
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 3879368..3890492

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NI25_RS16985 (NI25_16895)	-	3879531..3880343 (+)	813	WP_061443260.1	hypothetical protein	-
NI25_RS16990 (NI25_16900)	-	3880492..3882276 (-)	1785	WP_061443261.1	BACON domain-containing protein	-
NI25_RS16995 (NI25_16905)	radA/sms	3882877..3884286 (+)	1410	WP_061443262.1	DNA repair protein RadA	Machinery gene
NI25_RS17000 (NI25_16910)	disA	3884368..3885492 (+)	1125	WP_030404779.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
NI25_RS39705 (NI25_16915)	-	3885513..3886355 (-)	843	WP_078884643.1	hypothetical protein	-
NI25_RS17010 (NI25_16920)	-	3886513..3887439 (+)	927	WP_061443263.1	A/G-specific adenine glycosylase	-
NI25_RS17015 (NI25_16925)	-	3887717..3888250 (+)	534	WP_003975479.1	SigE family RNA polymerase sigma factor	-
NI25_RS17020 (NI25_16930)	-	3888238..3888936 (+)	699	WP_199560937.1	hypothetical protein	-
NI25_RS17025 (NI25_16935)	cseB	3889071..3889772 (+)	702	WP_061443265.1	two-component system response regulator CseB	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40084.82 Da
• Isoelectric Point: 5.0058

>NTDB_id=113389 NI25_RS17000 WP_030404779.1 3884368..3885492(+) (disA) [Streptomyces sp. CCM_MD2014]
MAANDRAAAPGKSGGSAGADGLMRASLSAVAPGTSLRDGLERVLRGNTGGLIVLGSDKTVEQMCTGGFVLDVEFTATRLR
ELCKLDGGIVLSSDLSKILRAGVQLLPDPTIPTEETGTRHRTADRVSKQVGFPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVDEALAELDKLSHAELLELSTVARALGYTGSPETLDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=113389 NI25_RS17000 WP_030404779.1 3884368..3885492(+) (disA) [Streptomyces sp. CCM_MD2014]
GTGGCAGCCAACGACCGGGCAGCAGCTCCCGGAAAGTCCGGTGGGAGTGCCGGTGCCGATGGCCTGATGCGCGCCTCACT
GAGCGCCGTGGCGCCCGGCACGTCCCTGCGCGACGGCCTGGAGCGGGTCCTGCGCGGCAACACGGGCGGTCTGATCGTGC
TGGGCTCCGACAAGACCGTCGAGCAGATGTGCACGGGCGGTTTCGTGCTGGACGTCGAGTTCACCGCGACCCGGCTGCGC
GAGCTGTGCAAGCTCGACGGCGGCATCGTGCTCTCGTCCGACCTGTCGAAGATCCTGCGGGCCGGGGTGCAGCTGCTTCC
CGATCCGACCATCCCCACGGAGGAGACCGGCACGCGGCACCGCACGGCGGACCGGGTCAGCAAGCAGGTCGGGTTCCCCG
TCGTGTCGGTGTCGCAGTCGATGCGGCTGATCGCGCTGTACGTGGACGGGCAGCGGCGGGTGCTGGAGGATTCGGCGGCG
ATCCTGTCGCGGGCCAATCAGGCGCTGGCGACGCTGGAGCGGTACAAGCTGCGCCTCGACGAGGTCGCGGGCACGCTGTC
GGCGCTGGAGATCGAGGACCTGGTGACGGTGCGGGACGTCTCCGCGGTCGCGCAGCGGCTGGAGATGGTGCGCCGGATCG
CCACCGAGATCGCCGAGTACGTGGTGGAGCTGGGGACGGACGGGCGGCTGCTCGCGCTGCAGTTGGACGAGCTGATCGCC
GGGGTGGAGCCGGAGCGCGAGCTGGTGGTGCGGGACTACGTGCCCGAGCCGACCGCCAAGCGGTCCCGCACGGTCGACGA
GGCGCTCGCCGAGCTGGACAAGCTCAGCCATGCGGAACTGCTGGAACTGTCCACGGTGGCCCGGGCGTTGGGTTACACCG
GGTCGCCGGAGACGCTGGACTCGGCGGTGTCGCCGCGCGGCTTCCGGCTGCTGGCCAAGGTGCCGCGGCTGCCCGGCGCG
ATCATCGACCGGCTGGTGGAGCACTTCGGCGGCCTGCAGAAGCTGCTCGCCGCCAGTGTCGACGACCTGCAGACCGTGGA
CGGCGTCGGCGAGGCGCGGGCGCGCAGCGTGCGCGAGGGGCTGTCGCGGCTGGCGGAGTCGTCGATCCTGGAGCGCTACG
TCTGA

Domains

Predicted by InterProScan.

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

3D structure

• AlphaFold DB: A0A6B3QRH4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	46.26	96.524	0.447