Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   H1W80_RS02905 Genome accession   NZ_LR822040
Coordinates   540390..541616 (+) Length   408 a.a.
NCBI ID   WP_180473452.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_1125     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 535390..546616
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W80_RS02880 (STHERMO_0608) - 535965..537236 (-) 1272 WP_180473449.1 hydroxymethylglutaryl-CoA reductase, degradative -
  H1W80_RS02885 (STHERMO_0609) - 537229..538404 (-) 1176 WP_180473450.1 hydroxymethylglutaryl-CoA synthase -
  H1W80_RS02890 (STHERMO_0610) - 538726..539586 (+) 861 WP_002950145.1 thymidylate synthase -
  H1W80_RS02895 (STHERMO_0611) - 539694..540197 (+) 504 WP_180473451.1 dihydrofolate reductase -
  H1W80_RS02900 (STHERMO_0612) - 540202..540372 (+) 171 WP_002886174.1 hypothetical protein -
  H1W80_RS02905 (STHERMO_0613) clpX 540390..541616 (+) 1227 WP_180473452.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  H1W80_RS02910 (STHERMO_0614) yihA 541626..542225 (+) 600 WP_002950154.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  H1W80_RS02915 (STHERMO_0615) - 542355..543731 (+) 1377 WP_082308861.1 amino acid permease -
  H1W80_RS02920 (STHERMO_0616) mmuM 543743..544693 (+) 951 WP_087009767.1 homocysteine S-methyltransferase -
  H1W80_RS02925 (STHERMO_0617) - 544806..545060 (+) 255 WP_002950164.1 DUF1912 family protein -
  H1W80_RS02930 (STHERMO_0618) - 545132..545491 (+) 360 WP_002950165.1 helix-hairpin-helix domain-containing protein -
  H1W80_RS02935 (STHERMO_0619) plsY 545605..546246 (-) 642 WP_022096963.1 glycerol-3-phosphate 1-O-acyltransferase PlsY -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45033.51 Da        Isoelectric Point: 4.4432

>NTDB_id=1131993 H1W80_RS02905 WP_180473452.1 540390..541616(+) (clpX) [Streptococcus thermophilus isolate STH_CIRM_1125]
MAGNRNEEMVYCSFCGKNQEEVKKIIAGNGVFICNECVALSQEIIREETAEEVLADLAETPKPKELLDILNNYVVGQDRV
KRALAVAVYNHYKRINFTESREDNDVDLQKSNILMIGPTGSGKTYLAQTLARSLNVPFAIADATSLTEAGYVGEDVENIL
LKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIKIDTKN
ILFIVGGAFDGIEDIVKQRLGEKIIGFGQNNKAIDDESSYMKEIVAEDIQKFGLIPEFIGRLPVLAALEQLTVDDLVRIL
TEPRNALVKQYQTLLSYDGVELEFDQDALEAIASKAIERKTGARGLRSIIEEVMMDVMFEIPSLEDVTKVRITKEAVDGK
AAPVLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=1131993 H1W80_RS02905 WP_180473452.1 540390..541616(+) (clpX) [Streptococcus thermophilus isolate STH_CIRM_1125]
ATGGCTGGAAATCGTAATGAAGAGATGGTTTATTGTTCATTTTGTGGCAAAAACCAAGAAGAAGTGAAGAAAATTATCGC
CGGTAATGGCGTCTTTATCTGTAACGAATGTGTGGCCTTGTCACAAGAAATCATTCGTGAGGAAACGGCTGAAGAAGTTT
TAGCTGACTTGGCTGAAACGCCAAAGCCAAAAGAACTTTTAGATATTTTGAACAACTATGTCGTGGGGCAAGATCGTGTC
AAACGTGCCTTGGCAGTAGCTGTTTACAACCACTATAAACGTATCAACTTCACAGAAAGTCGTGAAGATAATGATGTGGA
CTTGCAAAAATCAAATATCCTCATGATTGGACCAACAGGGTCAGGGAAAACTTACTTAGCTCAGACTTTGGCTCGTAGTT
TGAATGTTCCTTTCGCGATTGCGGATGCGACATCATTGACAGAGGCAGGTTATGTGGGTGAGGATGTGGAAAATATCCTC
CTCAAACTAATCCAAGCGGCAGACTTTAATATTGAACGTGCGGAACGTGGGATTATCTACGTGGACGAGATTGATAAGAT
TGCCAAAAAAGGTGAGAATGTTTCAATCACTCGTGATGTTTCAGGTGAAGGGGTTCAACAAGCTCTCTTGAAGATTATTG
AGGGAACAGTGGCTAGTGTTCCACCTCAAGGTGGTCGTAAACACCCTAATCAAGAGATGATTAAAATTGATACTAAGAAT
ATTCTCTTTATCGTGGGTGGTGCTTTTGATGGTATCGAAGATATCGTTAAGCAACGTCTTGGTGAGAAAATCATTGGGTT
TGGTCAAAATAATAAAGCAATTGATGACGAATCATCATACATGAAAGAAATTGTGGCTGAAGATATCCAAAAATTTGGAC
TTATCCCTGAATTTATCGGACGTTTGCCAGTTCTTGCGGCCCTTGAACAGTTAACGGTTGACGACTTGGTGCGTATTTTG
ACAGAGCCTAGGAATGCCTTGGTGAAGCAGTATCAAACCCTCTTGTCTTATGATGGGGTTGAACTTGAGTTTGACCAGGA
TGCCCTTGAGGCTATTGCAAGTAAGGCAATTGAACGTAAGACTGGTGCGCGTGGGCTTCGCTCTATCATTGAAGAAGTCA
TGATGGATGTTATGTTTGAAATCCCTAGTCTGGAAGATGTCACTAAGGTTCGTATCACCAAAGAAGCTGTTGATGGGAAA
GCTGCTCCAGTATTGGAAACAGCATAA

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-388)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

88.509

100

0.887
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.511

99.755

0.564

Multiple sequence alignment