Detailed information    

insolico Bioinformatically predicted

Overview

Name   amiE   Type   Regulator
Locus tag   H1W92_RS06760 Genome accession   NZ_LR822039
Coordinates   1285431..1286516 (-) Length   361 a.a.
NCBI ID   WP_011226304.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_1116     
Function   internalize XIP (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 1268975..1340749 1285431..1286516 within 0


Gene organization within MGE regions


Location: 1268975..1340749
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W92_RS06680 (STHERMO_1457) liaF 1268983..1269681 (-) 699 WP_011226289.1 cell wall-active antibiotics response protein LiaF -
  H1W92_RS09910 (STHERMO_1458) - 1269947..1270102 (-) 156 WP_011226290.1 ion channel -
  H1W92_RS06690 (STHERMO_1461) stkP/pknB 1270739..1272610 (-) 1872 WP_011226292.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  H1W92_RS06695 (STHERMO_1462) - 1272610..1273347 (-) 738 WP_002946881.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  H1W92_RS06700 (STHERMO_1463) rsmB 1273391..1274713 (-) 1323 WP_014608533.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  H1W92_RS06705 (STHERMO_1464) fmt 1274703..1275638 (-) 936 WP_002951411.1 methionyl-tRNA formyltransferase -
  H1W92_RS06710 (STHERMO_1465) - 1275656..1278052 (-) 2397 WP_011227404.1 primosomal protein N' -
  H1W92_RS06715 (STHERMO_1466) rpoZ 1278194..1278508 (-) 315 WP_002951415.1 DNA-directed RNA polymerase subunit omega -
  H1W92_RS06720 (STHERMO_1467) gmk 1278530..1279159 (-) 630 WP_011226296.1 guanylate kinase -
  H1W92_RS06725 (STHERMO_1468) ftsY 1279392..1280783 (-) 1392 WP_011226297.1 signal recognition particle-docking protein FtsY -
  H1W92_RS06730 (STHERMO_1469) - 1280797..1281612 (-) 816 WP_011227405.1 Cof-type HAD-IIB family hydrolase -
  H1W92_RS06735 (STHERMO_1470) - 1281605..1282399 (-) 795 WP_059257398.1 HAD hydrolase family protein -
  H1W92_RS06740 (STHERMO_1471) - 1282582..1282959 (+) 378 WP_011226300.1 GntR family transcriptional regulator -
  H1W92_RS06745 (STHERMO_1472) - 1282964..1283662 (+) 699 WP_011226301.1 ABC transporter ATP-binding protein -
  H1W92_RS06750 (STHERMO_1473) - 1283674..1284459 (+) 786 WP_002951425.1 hypothetical protein -
  H1W92_RS06755 (STHERMO_1474) amiF 1284509..1285438 (-) 930 WP_002951426.1 ATP-binding cassette domain-containing protein Regulator
  H1W92_RS06760 (STHERMO_1475) amiE 1285431..1286516 (-) 1086 WP_011226304.1 ABC transporter ATP-binding protein Regulator
  H1W92_RS06765 (STHERMO_1476) amiD 1286526..1287452 (-) 927 WP_002946409.1 oligopeptide ABC transporter permease OppC Regulator
  H1W92_RS06770 (STHERMO_1477) amiC 1287452..1288945 (-) 1494 WP_011227407.1 ABC transporter permease Regulator
  H1W92_RS06775 (STHERMO_1478) amiA 1289007..1290974 (-) 1968 WP_180475749.1 peptide ABC transporter substrate-binding protein Regulator
  H1W92_RS06785 - 1291330..1292579 (+) 1250 Protein_1276 ISL3 family transposase -
  H1W92_RS06790 (STHERMO_1480) amiA3 1292624..1294591 (-) 1968 WP_011227411.1 peptide ABC transporter substrate-binding protein Regulator
  H1W92_RS06795 - 1294795..1294985 (-) 191 Protein_1278 IS3 family transposase -
  H1W92_RS09915 - 1294979..1295389 (-) 411 Protein_1279 ATP-binding cassette domain-containing protein -
  H1W92_RS06810 (STHERMO_1483) - 1295421..1295735 (-) 315 Protein_1280 TatD family hydrolase -
  H1W92_RS06815 (STHERMO_1484) - 1296084..1297289 (+) 1206 WP_011227415.1 OFA family MFS transporter -
  H1W92_RS06820 - 1297335..1298687 (-) 1353 Protein_1282 IS3 family transposase -
  H1W92_RS06825 (STHERMO_1489) pta 1298773..1299756 (-) 984 WP_011227420.1 phosphate acetyltransferase -
  H1W92_RS06830 (STHERMO_1490) - 1299770..1300666 (-) 897 WP_011226316.1 RluA family pseudouridine synthase -
  H1W92_RS06835 (STHERMO_1491) - 1300663..1301499 (-) 837 WP_041827075.1 NAD kinase -
  H1W92_RS06840 (STHERMO_1492) - 1301471..1302145 (-) 675 WP_002951443.1 GTP pyrophosphokinase family protein -
  H1W92_RS06845 (STHERMO_1493) - 1302241..1302816 (+) 576 WP_002951444.1 CYTH domain-containing protein -
  H1W92_RS06850 (STHERMO_1494) - 1303179..1304150 (+) 972 WP_002951446.1 ribose-phosphate diphosphokinase -
  H1W92_RS06855 (STHERMO_1495) - 1304154..1305266 (+) 1113 WP_002948029.1 cysteine desulfurase family protein -
  H1W92_RS06860 (STHERMO_1496) - 1305268..1305615 (+) 348 WP_002948028.1 DUF1831 domain-containing protein -
  H1W92_RS06865 (STHERMO_1497) - 1305759..1306418 (+) 660 WP_041827076.1 redox-sensing transcriptional repressor Rex -
  H1W92_RS06870 (STHERMO_1498) - 1306411..1307106 (+) 696 WP_011227423.1 gamma-glutamyl-gamma-aminobutyrate hydrolase family protein -
  H1W92_RS06875 (STHERMO_1499) radC 1307159..1307845 (-) 687 WP_011227424.1 RadC family protein -
  H1W92_RS06880 (STHERMO_1500) - 1308024..1309364 (-) 1341 WP_231108743.1 DUF2142 domain-containing protein -
  H1W92_RS06885 (STHERMO_1501) - 1309513..1311258 (-) 1746 WP_011227426.1 rhamnan synthesis F family protein -
  H1W92_RS06890 (STHERMO_1502) - 1311260..1312960 (-) 1701 WP_041827077.1 glycosyltransferase family 4 protein -
  H1W92_RS06895 (STHERMO_1503) - 1312978..1314180 (-) 1203 WP_059257395.1 ABC transporter ATP-binding protein -
  H1W92_RS06900 (STHERMO_1504) - 1314180..1314986 (-) 807 WP_011227429.1 ABC transporter permease -
  H1W92_RS06905 (STHERMO_1505) - 1314986..1315927 (-) 942 WP_011227430.1 glycosyltransferase family 2 protein -
  H1W92_RS06910 (STHERMO_1506) cps2T 1315924..1317072 (-) 1149 WP_011227431.1 beta 1-4 rhamnosyltransferase Cps2T -
  H1W92_RS06915 (STHERMO_1507) - 1317191..1317973 (-) 783 WP_011227432.1 glycosyltransferase family A protein -
  H1W92_RS06920 (STHERMO_1508) - 1317974..1318306 (-) 333 WP_011227433.1 DUF2304 domain-containing protein -
  H1W92_RS06925 (STHERMO_1509) - 1318312..1319007 (-) 696 WP_173405413.1 glycosyltransferase family 2 protein -
  H1W92_RS06930 - 1319091..1319563 (-) 473 Protein_1304 glycosyltransferase family 2 protein -
  H1W92_RS06935 (STHERMO_1512) - 1319628..1320614 (-) 987 WP_011227437.1 glycosyltransferase family 2 protein -
  H1W92_RS06940 (STHERMO_1513) - 1320611..1321870 (-) 1260 WP_011227438.1 oligosaccharide flippase family protein -
  H1W92_RS06945 (STHERMO_1514) rfbD 1321992..1322843 (-) 852 WP_014621820.1 dTDP-4-dehydrorhamnose reductase -
  H1W92_RS06950 (STHERMO_1515) - 1322961..1323887 (-) 927 WP_011227439.1 glycosyltransferase family 2 protein -
  H1W92_RS06955 (STHERMO_1516) - 1323897..1324232 (-) 336 WP_002891474.1 metal-sulfur cluster assembly factor -
  H1W92_RS06960 (STHERMO_1517) rpoD 1324286..1325395 (-) 1110 WP_011227440.1 RNA polymerase sigma factor RpoD -
  H1W92_RS06965 (STHERMO_1518) dnaG 1325399..1327210 (-) 1812 WP_011227441.1 DNA primase -
  H1W92_RS06970 (STHERMO_1519) rpsU 1327582..1327758 (-) 177 WP_011226340.1 30S ribosomal protein S21 -
  H1W92_RS06975 (STHERMO_1520) - 1328139..1329092 (+) 954 WP_041826943.1 IS30 family transposase -
  H1W92_RS06980 (STHERMO_1521) - 1329198..1329992 (-) 795 WP_011227442.1 ABC transporter substrate-binding protein -
  H1W92_RS06985 (STHERMO_1522) - 1330085..1331194 (-) 1110 WP_041828295.1 aminotransferase -
  H1W92_RS06990 (STHERMO_1523) - 1331541..1332338 (-) 798 WP_059257394.1 transporter substrate-binding domain-containing protein -
  H1W92_RS06995 (STHERMO_1524) - 1332335..1333165 (-) 831 WP_041828297.1 transporter substrate-binding domain-containing protein -
  H1W92_RS07000 (STHERMO_1525) - 1333379..1333843 (-) 465 WP_011226345.1 8-oxo-dGTP diphosphatase -
  H1W92_RS07005 (STHERMO_1526) uvrB 1333888..1335879 (-) 1992 WP_002953358.1 excinuclease ABC subunit UvrB -
  H1W92_RS10230 - 1336566..1337502 (-) 937 Protein_1320 CPBP family intramembrane glutamic endopeptidase -
  H1W92_RS07020 (STHERMO_1531) - 1337701..1339911 (+) 2211 WP_011226350.1 ABC transporter substrate-binding protein/permease -
  H1W92_RS07025 (STHERMO_1532) - 1339911..1340651 (+) 741 WP_002945131.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 361 a.a.        Molecular weight: 39864.62 Da        Isoelectric Point: 4.7435

>NTDB_id=1131949 H1W92_RS06760 WP_011226304.1 1285431..1286516(-) (amiE) [Streptococcus thermophilus isolate STH_CIRM_1116]
MTENKNVILSARDIVVEFDVRDRVLTAIRGVSLDLVEGEVLALVGESGSGKSVLTKTFTGMLEENGRVASGSIDYRGKDL
TKFKSHQDWAAIRGAKIATIFQDPMTSLNPIKTIGSQIIEVIVKHQGKTAKEAKKMAIDYMDKVGIPDAEKRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLKEEYGFSVIFITHDLGVVASIADKVAVMYAGEIIE
YATVEEIFYEPCHPYTWSLLSSLPQLADDNGKLFSIPGTPPSLYTPVVGDAFALRSDYALQIDFEEKAPQFQVSDTHWAK
TWLLHEDAPKVDKPAVIQNLHEKILANMGFAHLGDEEEGNA

Nucleotide


Download         Length: 1086 bp        

>NTDB_id=1131949 H1W92_RS06760 WP_011226304.1 1285431..1286516(-) (amiE) [Streptococcus thermophilus isolate STH_CIRM_1116]
ATGACAGAAAATAAAAATGTAATATTATCGGCTCGCGATATCGTCGTGGAATTTGACGTTCGTGACCGTGTTTTGACAGC
TATTCGAGGGGTTTCTCTTGATTTAGTTGAAGGTGAAGTTTTAGCCTTGGTTGGTGAGTCTGGTTCAGGAAAATCAGTCT
TGACTAAAACTTTTACAGGGATGCTGGAAGAAAATGGTCGTGTAGCTAGCGGATCTATCGACTACCGTGGCAAAGACTTG
ACTAAATTTAAGAGTCACCAAGATTGGGCAGCTATCCGTGGAGCTAAGATTGCAACTATTTTCCAAGATCCAATGACCAG
TCTTAACCCAATTAAGACTATCGGAAGTCAAATTATTGAAGTTATTGTTAAGCACCAAGGGAAAACAGCCAAGGAAGCTA
AAAAAATGGCAATTGATTACATGGACAAGGTTGGTATTCCAGATGCTGAAAAACGTTTCAATGAATATCCTTTCCAATAC
TCTGGTGGGATGCGTCAACGTATCGTTATTGCCATTGCCTTGGCTTGTCGTCCTGATGTCCTTATCTGTGACGAACCAAC
AACTGCCCTTGATGTGACCATTCAAGCTCAAATCATTGACCTCTTGAAATCACTCAAAGAGGAGTATGGTTTCTCGGTCA
TTTTCATTACCCATGACCTTGGCGTCGTAGCAAGTATCGCGGACAAGGTTGCTGTCATGTATGCTGGCGAAATCATTGAA
TACGCAACTGTTGAGGAAATTTTCTATGAGCCTTGTCATCCATACACGTGGAGCTTGCTTTCAAGTCTGCCACAATTGGC
TGATGATAATGGAAAACTCTTCTCAATTCCAGGGACGCCACCATCACTTTATACACCAGTTGTTGGGGATGCCTTTGCCT
TGCGTTCAGATTATGCTTTGCAGATTGATTTTGAGGAAAAAGCACCACAATTCCAAGTTTCAGATACTCACTGGGCTAAG
ACCTGGCTCTTACATGAGGATGCGCCAAAAGTTGATAAACCTGCGGTTATCCAAAATCTACATGAAAAAATCCTAGCCAA
TATGGGATTTGCACATTTAGGAGATGAGGAGGAAGGCAATGCCTGA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(29-187)

Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY)

(239-300)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  amiE Streptococcus thermophilus LMG 18311

100

100

1
  amiE Streptococcus thermophilus LMD-9

100

100

1
  amiE Streptococcus salivarius strain HSISS4

96.953

100

0.97
  oppD Streptococcus mutans UA159

54.441

96.676

0.526

Multiple sequence alignment