Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   H1W90_RS02890 Genome accession   NZ_LR822033
Coordinates   550805..552031 (+) Length   408 a.a.
NCBI ID   WP_116920144.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_1048     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 545805..557031
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W90_RS02865 (STHERMO_0621) - 546380..547651 (-) 1272 WP_179971487.1 hydroxymethylglutaryl-CoA reductase, degradative -
  H1W90_RS02870 (STHERMO_0622) - 547644..548819 (-) 1176 WP_180481242.1 hydroxymethylglutaryl-CoA synthase -
  H1W90_RS02875 (STHERMO_0623) - 549141..550001 (+) 861 WP_002950145.1 thymidylate synthase -
  H1W90_RS02880 (STHERMO_0624) - 550109..550612 (+) 504 WP_002950147.1 dihydrofolate reductase -
  H1W90_RS02885 (STHERMO_0625) - 550617..550787 (+) 171 WP_002886174.1 hypothetical protein -
  H1W90_RS02890 (STHERMO_0626) clpX 550805..552031 (+) 1227 WP_116920144.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  H1W90_RS02895 (STHERMO_0627) yihA 552044..552643 (+) 600 WP_002950154.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  H1W90_RS02900 (STHERMO_0628) - 552773..554149 (+) 1377 WP_180481243.1 amino acid permease -
  H1W90_RS02905 (STHERMO_0629) mmuM 554161..555111 (+) 951 WP_180481244.1 homocysteine S-methyltransferase -
  H1W90_RS02910 (STHERMO_0630) - 555224..555478 (+) 255 WP_002950164.1 DUF1912 family protein -
  H1W90_RS02915 (STHERMO_0631) - 555550..555909 (+) 360 WP_002950165.1 helix-hairpin-helix domain-containing protein -
  H1W90_RS02920 (STHERMO_0632) plsY 556023..556664 (-) 642 WP_002950167.1 glycerol-3-phosphate 1-O-acyltransferase PlsY -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45051.50 Da        Isoelectric Point: 4.4119

>NTDB_id=1131636 H1W90_RS02890 WP_116920144.1 550805..552031(+) (clpX) [Streptococcus thermophilus isolate STH_CIRM_1048]
MAGNRNEEMVYCSFCGKNQEEVKKIIAGNGVFICNECVALSQEIIREETAEEVLADLAETPKPKELLDILNNYVVGQDRV
KRALAVAVYNHYKRINFTESREDNDVDLQKSNILMIGPTGSGKTYLAQTLARSLNVPFAIADATSLTEAGYVGEDVENIL
LKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKN
ILFIVGGAFDGIEDIVKQRLGEKIIGFGQNNKAIDDESSYMKEIVAEDIQKFGLIPEFIGRLPVLAALEQLTVDDLVRIL
TEPRNALVKQYQTLLSYDGVELEFDQDALEAIASKAIERKTGARGLRSIIEEVMMDVMFEIPSMEDVTKVRITKEAVDGK
AAPVLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=1131636 H1W90_RS02890 WP_116920144.1 550805..552031(+) (clpX) [Streptococcus thermophilus isolate STH_CIRM_1048]
ATGGCTGGAAATCGTAATGAAGAGATGGTTTATTGTTCATTTTGTGGCAAAAACCAAGAAGAAGTGAAGAAAATTATCGC
CGGTAATGGCGTCTTTATCTGTAACGAATGTGTGGCCTTGTCACAAGAAATCATTCGTGAGGAAACGGCTGAAGAAGTTT
TAGCTGACTTGGCTGAAACGCCAAAGCCAAAAGAACTTTTAGATATTTTGAACAACTATGTCGTGGGGCAAGATCGTGTC
AAACGTGCCTTGGCAGTAGCTGTTTACAACCACTATAAACGTATCAACTTCACAGAAAGTCGTGAAGATAATGATGTGGA
CTTGCAAAAATCAAATATCCTCATGATTGGACCAACAGGGTCAGGGAAAACTTACTTAGCTCAGACTTTGGCTCGTAGTT
TGAATGTTCCTTTCGCGATTGCGGATGCGACATCATTGACAGAGGCAGGTTATGTGGGTGAGGATGTGGAAAATATCCTC
CTCAAACTAATTCAAGCGGCAGACTTTAATATTGAACGTGCGGAACGTGGGATTATCTACGTGGACGAGATTGATAAGAT
TGCCAAAAAAGGTGAGAATGTTTCAATCACTCGTGATGTTTCAGGTGAAGGGGTTCAACAAGCTCTCTTGAAGATTATTG
AGGGAACAGTGGCTAGTGTTCCACCTCAAGGTGGTCGTAAACACCCTAATCAAGAGATGATTCAAATTGATACTAAGAAT
ATTCTCTTTATCGTGGGTGGTGCTTTTGATGGTATCGAAGATATCGTTAAGCAACGTCTTGGTGAGAAAATCATTGGGTT
TGGTCAAAATAATAAAGCAATTGATGACGAATCATCATACATGAAAGAAATTGTGGCTGAAGATATCCAAAAATTTGGAC
TTATCCCTGAATTTATCGGACGTTTGCCAGTTCTTGCGGCCCTTGAACAGTTAACGGTTGACGACTTGGTGCGTATTTTG
ACAGAGCCTAGGAATGCCTTGGTGAAGCAGTATCAAACCCTCTTGTCTTATGATGGGGTTGAACTTGAGTTTGACCAGGA
TGCCCTTGAGGCTATTGCAAGTAAGGCAATTGAACGTAAGACTGGTGCGCGTGGGCTTCGCTCTATCATTGAAGAAGTCA
TGATGGATGTTATGTTTGAAATCCCTAGTATGGAAGATGTCACTAAGGTTCGTATCACCAAAGAAGCTGTTGATGGGAAA
GCTGCTCCAGTATTGGAAACAGCATAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

88.753

100

0.89
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.757

99.755

0.566

Multiple sequence alignment