Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   H1W91_RS03000 Genome accession   NZ_LR822032
Coordinates   563723..564949 (+) Length   408 a.a.
NCBI ID   WP_180476871.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_1050     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 558723..569949
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W91_RS02975 (STHERMO_0628) - 559298..560569 (-) 1272 WP_173940513.1 hydroxymethylglutaryl-CoA reductase, degradative -
  H1W91_RS02980 (STHERMO_0629) - 560562..561737 (-) 1176 WP_011680902.1 hydroxymethylglutaryl-CoA synthase -
  H1W91_RS02985 (STHERMO_0630) - 562059..562919 (+) 861 WP_180476869.1 thymidylate synthase -
  H1W91_RS02990 (STHERMO_0631) - 563027..563530 (+) 504 WP_002950147.1 dihydrofolate reductase -
  H1W91_RS02995 (STHERMO_0632) - 563535..563705 (+) 171 WP_180476870.1 hypothetical protein -
  H1W91_RS03000 (STHERMO_0633) clpX 563723..564949 (+) 1227 WP_180476871.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  H1W91_RS03005 (STHERMO_0634) yihA 564959..565558 (+) 600 WP_002950154.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  H1W91_RS03010 (STHERMO_0635) - 565688..567064 (+) 1377 WP_180476872.1 amino acid permease -
  H1W91_RS03015 (STHERMO_0636) mmuM 567076..568026 (+) 951 WP_011680907.1 homocysteine S-methyltransferase -
  H1W91_RS03020 (STHERMO_0637) - 568139..568393 (+) 255 WP_002950164.1 DUF1912 family protein -
  H1W91_RS03025 (STHERMO_0638) - 568465..568824 (+) 360 WP_002950165.1 helix-hairpin-helix domain-containing protein -
  H1W91_RS03030 (STHERMO_0639) plsY 568938..569579 (-) 642 WP_002950167.1 glycerol-3-phosphate 1-O-acyltransferase PlsY -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45093.52 Da        Isoelectric Point: 4.4119

>NTDB_id=1131575 H1W91_RS03000 WP_180476871.1 563723..564949(+) (clpX) [Streptococcus thermophilus isolate STH_CIRM_1050]
MTGNRNEEMVYCSFCGKNQEEVKKIIAGNGVFICNECVALSQEIIREETAEEVLADLAETPKPKELLDILNNYVVGQDRV
KRALAVAVYNHYKRINFTESREDNDVDLQKSNILMIGPTGSGKTYLAQTLARSLNVPFAIADATSLTEAGYVGEDVENIL
LKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKN
ILFIVGGAFDGIEDIVKQRLGEKIIGFGQNNKAIDDESSYMKEIVAEDIQKFGLIPEFIGRLPVLATLEQLTVDDLVRIL
TEPRNALVKQYQTLLSYDGVELEFDQDALEAIASKAIERKTGARGLRSIIEEVMMDVMFEIPSLEDVTKVRITKEAVDGK
AAPVLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=1131575 H1W91_RS03000 WP_180476871.1 563723..564949(+) (clpX) [Streptococcus thermophilus isolate STH_CIRM_1050]
ATGACTGGAAATCGTAATGAAGAGATGGTTTATTGTTCATTTTGTGGCAAAAACCAAGAAGAAGTGAAGAAAATTATCGC
CGGTAATGGCGTCTTTATCTGTAACGAATGTGTGGCCTTGTCACAAGAAATCATTCGTGAGGAAACGGCTGAAGAAGTTT
TAGCTGACTTGGCTGAAACGCCAAAGCCAAAAGAACTTTTAGATATTTTGAACAACTATGTCGTGGGGCAAGATCGTGTC
AAACGTGCCTTGGCAGTAGCTGTTTACAACCACTATAAACGTATCAACTTCACAGAAAGTCGTGAAGATAATGATGTGGA
CTTGCAAAAATCAAATATCCTCATGATTGGACCAACAGGGTCAGGGAAAACTTACTTAGCTCAGACTTTGGCTCGTAGTT
TGAATGTTCCTTTCGCGATTGCGGATGCGACATCATTGACAGAGGCAGGTTATGTGGGTGAGGATGTGGAAAATATCCTC
CTCAAACTAATTCAAGCGGCAGACTTTAATATTGAACGTGCGGAACGTGGGATTATCTACGTGGACGAGATTGATAAGAT
TGCCAAAAAAGGTGAGAATGTTTCAATCACTCGTGATGTTTCAGGTGAAGGGGTTCAACAAGCTCTCTTGAAGATTATTG
AGGGAACAGTGGCTAGTGTTCCACCTCAAGGTGGTCGTAAACACCCTAATCAAGAGATGATTCAAATTGATACTAAGAAT
ATTCTCTTTATCGTGGGTGGTGCTTTTGATGGTATCGAAGATATCGTTAAGCAACGTCTTGGTGAGAAAATCATTGGGTT
TGGTCAAAATAATAAAGCAATTGATGACGAATCATCATACATGAAAGAAATTGTGGCTGAAGATATCCAAAAATTTGGAC
TTATCCCTGAATTTATCGGACGTTTGCCAGTTCTTGCGACCCTTGAACAGTTAACGGTCGACGACTTGGTGCGTATTTTG
ACAGAGCCTAGGAATGCCTTGGTGAAGCAGTATCAAACCCTCTTGTCTTATGATGGGGTTGAACTTGAGTTTGACCAGGA
TGCCCTTGAGGCTATTGCAAGTAAGGCAATTGAACGTAAGACTGGTGCGCGTGGGCTTCGCTCTATCATTGAAGAAGTCA
TGATGGATGTTATGTTTGAAATCCCTAGTCTGGAAGATGTCACTAAGGTTCGTATCACCAAAGAAGCTGTTGATGGGAAA
GCTGCTCCAGTATTGGAAACAGCATAA

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-388)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

88.264

100

0.885
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.757

99.755

0.566

Multiple sequence alignment