Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   H1W74_RS02890 Genome accession   NZ_LR822031
Coordinates   546072..547298 (+) Length   408 a.a.
NCBI ID   WP_011680904.1    Uniprot ID   Q03LN0
Organism   Streptococcus thermophilus isolate STH_CIRM_1047     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 541072..552298
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W74_RS02865 (STHERMO_0623) - 541647..542918 (-) 1272 WP_022096960.1 hydroxymethylglutaryl-CoA reductase, degradative -
  H1W74_RS02870 (STHERMO_0624) - 542911..544086 (-) 1176 WP_011680902.1 hydroxymethylglutaryl-CoA synthase -
  H1W74_RS02875 (STHERMO_0625) - 544408..545268 (+) 861 WP_002950145.1 thymidylate synthase -
  H1W74_RS02880 (STHERMO_0626) - 545376..545879 (+) 504 WP_002945725.1 dihydrofolate reductase -
  H1W74_RS02885 (STHERMO_0627) - 545884..546054 (+) 171 WP_002886174.1 hypothetical protein -
  H1W74_RS02890 (STHERMO_0628) clpX 546072..547298 (+) 1227 WP_011680904.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  H1W74_RS02895 (STHERMO_0629) yihA 547308..547907 (+) 600 WP_002950154.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  H1W74_RS02900 (STHERMO_0630) - 548037..549413 (+) 1377 WP_022096961.1 amino acid permease -
  H1W74_RS02905 (STHERMO_0631) mmuM 549425..550375 (+) 951 WP_022096962.1 homocysteine S-methyltransferase -
  H1W74_RS02910 (STHERMO_0632) - 550488..550742 (+) 255 WP_002950164.1 DUF1912 family protein -
  H1W74_RS02915 (STHERMO_0633) - 550814..551173 (+) 360 WP_002950165.1 helix-hairpin-helix domain-containing protein -
  H1W74_RS02920 (STHERMO_0634) plsY 551287..551928 (-) 642 WP_022096963.1 glycerol-3-phosphate 1-O-acyltransferase PlsY -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45033.47 Da        Isoelectric Point: 4.4119

>NTDB_id=1131518 H1W74_RS02890 WP_011680904.1 546072..547298(+) (clpX) [Streptococcus thermophilus isolate STH_CIRM_1047]
MAGNRNEEMVYCSFCGKNQEEVKKIIAGNGVFICNECVALSQEIIREETAEEVLADLAETPKPKELLDILNNYVVGQDRV
KRALAVAVYNHYKRINFTESREDNDVDLQKSNILMIGPTGSGKTYLAQTLARSLNVPFAIADATSLTEAGYVGEDVENIL
LKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKN
ILFIVGGAFDGIEDIVKQRLGEKIIGFGQNNKAIDDESSYMKEIVAEDIQKFGLIPEFIGRLPVLAALEQLTVDDLVRIL
TEPRNALVKQYQTLLSYDGVELEFDQDALEAIASKAIERKTGARGLRSIIEEVMMDVMFEIPSLEDVTKVRITKEAVDGK
AAPVLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=1131518 H1W74_RS02890 WP_011680904.1 546072..547298(+) (clpX) [Streptococcus thermophilus isolate STH_CIRM_1047]
ATGGCTGGAAATCGTAATGAAGAGATGGTTTATTGTTCATTTTGTGGCAAAAACCAAGAAGAAGTGAAGAAAATTATCGC
CGGTAATGGCGTCTTTATCTGTAACGAATGTGTGGCCTTGTCACAAGAAATCATTCGTGAGGAAACGGCTGAAGAAGTTT
TAGCTGACTTGGCTGAAACGCCAAAGCCAAAAGAACTTTTAGATATTTTGAACAACTATGTCGTGGGGCAAGATCGTGTC
AAACGTGCCTTGGCAGTAGCTGTTTACAACCACTATAAACGTATCAACTTCACAGAAAGTCGTGAAGATAATGATGTGGA
CTTGCAAAAATCAAATATCCTCATGATTGGACCAACAGGGTCAGGGAAAACTTACTTAGCTCAGACTTTGGCTCGTAGTT
TGAATGTTCCTTTCGCGATTGCGGATGCGACATCATTGACAGAGGCAGGTTATGTGGGTGAGGATGTGGAAAATATCCTC
CTCAAACTAATCCAAGCGGCAGACTTTAATATTGAACGTGCGGAACGTGGGATTATCTACGTGGACGAGATTGATAAGAT
TGCCAAAAAAGGTGAGAATGTTTCAATCACTCGTGATGTTTCAGGTGAAGGGGTTCAACAAGCTCTCTTGAAGATTATTG
AGGGAACAGTGGCTAGCGTTCCACCTCAAGGTGGTCGTAAACACCCTAATCAAGAGATGATTCAAATTGATACTAAGAAC
ATTCTCTTTATCGTGGGTGGTGCTTTTGATGGTATCGAAGATATCGTTAAGCAACGTCTTGGTGAGAAAATCATTGGGTT
TGGTCAAAATAATAAAGCAATTGATGACGAATCATCATACATGAAAGAAATTGTGGCTGAAGATATCCAAAAATTTGGAC
TTATCCCTGAATTTATCGGACGTTTGCCAGTTCTTGCGGCCCTTGAACAGTTAACGGTTGACGACTTGGTACGTATTTTG
ACAGAGCCTAGGAATGCCTTGGTGAAGCAGTATCAAACCCTTTTGTCTTATGATGGGGTTGAACTTGAGTTTGACCAGGA
TGCCCTTGAGGCTATTGCAAGTAAGGCAATTGAACGTAAGACTGGTGCGCGTGGGCTTCGCTCTATCATTGAAGAAGTCA
TGATGGATGTTATGTTTGAAATCCCTAGTCTGGAAGATGTCACTAAGGTTCGTATCACCAAAGAAGCTGTTGATGGGAAA
GCTGCTCCAGTATTGGAAACAGCATAA

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-388)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q03LN0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

88.753

100

0.89
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.757

99.755

0.566

Multiple sequence alignment