Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   H1W95_RS02975 Genome accession   NZ_LR822030
Coordinates   568086..569312 (+) Length   408 a.a.
NCBI ID   WP_002950151.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_1046     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 563086..574312
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W95_RS02950 (STHERMO_0635) - 563661..564932 (-) 1272 WP_180483513.1 hydroxymethylglutaryl-CoA reductase, degradative -
  H1W95_RS02955 (STHERMO_0636) - 564925..566100 (-) 1176 WP_011680902.1 hydroxymethylglutaryl-CoA synthase -
  H1W95_RS02960 (STHERMO_0637) - 566422..567282 (+) 861 WP_002950145.1 thymidylate synthase -
  H1W95_RS02965 (STHERMO_0638) - 567390..567893 (+) 504 WP_134973137.1 dihydrofolate reductase -
  H1W95_RS02970 (STHERMO_0639) - 567898..568068 (+) 171 WP_002886174.1 hypothetical protein -
  H1W95_RS02975 (STHERMO_0640) clpX 568086..569312 (+) 1227 WP_002950151.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  H1W95_RS02980 (STHERMO_0641) yihA 569322..569921 (+) 600 WP_002950154.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  H1W95_RS02985 (STHERMO_0642) - 570051..571427 (+) 1377 WP_180483515.1 amino acid permease -
  H1W95_RS02990 (STHERMO_0643) mmuM 571439..572389 (+) 951 WP_041828170.1 homocysteine S-methyltransferase -
  H1W95_RS02995 (STHERMO_0644) - 572502..572756 (+) 255 WP_134973139.1 DUF1912 family protein -
  H1W95_RS03000 (STHERMO_0645) - 572828..573187 (+) 360 WP_002950165.1 helix-hairpin-helix domain-containing protein -
  H1W95_RS03005 (STHERMO_0646) plsY 573301..573942 (-) 642 WP_002950167.1 glycerol-3-phosphate 1-O-acyltransferase PlsY -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45063.49 Da        Isoelectric Point: 4.4119

>NTDB_id=1131457 H1W95_RS02975 WP_002950151.1 568086..569312(+) (clpX) [Streptococcus thermophilus isolate STH_CIRM_1046]
MAGNRNEEMVYCSFCGKNQEEVKKIIAGNGVFICNECVALSQEIIREETAEEVLADLAETPKPKELLDILNNYVVGQDRV
KRALAVAVYNHYKRINFTESREDNDVDLQKSNILMIGPTGSGKTYLAQTLARSLNVPFAIADATSLTEAGYVGEDVENIL
LKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKN
ILFIVGGAFDGIEDIVKQRLGEKIIGFGQNNKAIDDESSYMKEIVAEDIQKFGLIPEFIGRLPVLATLEQLTVDDLVRIL
TEPRNALVKQYQTLLSYDGVELEFDQDALEAIASKAIERKTGARGLRSIIEEVMMDVMFEIPSLEDVTKVRITKEAVDGK
AAPVLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=1131457 H1W95_RS02975 WP_002950151.1 568086..569312(+) (clpX) [Streptococcus thermophilus isolate STH_CIRM_1046]
ATGGCTGGAAATCGTAATGAAGAGATGGTTTATTGTTCATTTTGTGGCAAAAACCAAGAGGAAGTGAAGAAAATTATCGC
CGGTAATGGCGTCTTTATCTGTAACGAATGTGTGGCCTTGTCACAAGAAATCATTCGTGAGGAAACGGCTGAAGAAGTTT
TAGCTGACTTGGCTGAAACGCCAAAGCCAAAAGAACTTTTAGATATTTTGAACAACTATGTCGTGGGGCAAGATCGTGTC
AAACGTGCCTTGGCAGTAGCTGTTTACAACCACTATAAACGTATCAACTTCACAGAAAGTCGTGAAGATAATGATGTGGA
CTTGCAAAAATCAAATATCCTCATGATTGGACCAACAGGGTCAGGGAAAACTTACTTAGCTCAGACTTTGGCTCGTAGTT
TGAATGTTCCTTTCGCGATTGCGGATGCGACATCATTGACAGAGGCAGGTTATGTGGGTGAGGATGTGGAAAATATCCTC
CTCAAACTAATCCAAGCGGCAGACTTTAATATTGAACGTGCGGAACGTGGGATTATCTACGTGGACGAGATTGATAAGAT
TGCCAAAAAAGGTGAGAATGTTTCAATCACTCGTGATGTTTCAGGTGAAGGGGTTCAACAAGCTCTCTTGAAGATTATTG
AGGGAACAGTGGCTAGCGTTCCACCTCAAGGTGGTCGTAAACACCCTAATCAAGAGATGATTCAAATTGATACTAAGAAT
ATTCTCTTTATCGTGGGTGGTGCTTTTGATGGTATCGAAGATATCGTTAAGCAACGTCTTGGTGAGAAAATCATTGGGTT
TGGTCAAAATAATAAAGCAATTGATGACGAATCATCATACATGAAAGAAATTGTGGCTGAAGATATCCAAAAATTTGGAC
TTATCCCTGAATTTATCGGACGTTTGCCAGTTCTTGCGACCCTTGAACAGTTAACGGTTGACGACTTGGTGCGTATTTTG
ACAGAGCCTAGGAATGCCTTGGTGAAGCAGTATCAAACCCTCTTGTCTTATGATGGGGTTGAACTTGAGTTTGACCAGGA
TGCCCTTGAGGCTATTGCAAGTAAGGCAATTGAACGTAAGACTGGTGCGCGTGGGCTTCGCTCTATCATTGAAGAAGTCA
TGATGGATGTTATGTTTGAAATCCCTAGTCTGGAAGATGTCACTAAGGTTCGTATCACCAAAGAAGCTGTTGATGGGAAA
GCTGCTCCAGTATTGGAAACAGCATAA

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-388)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

88.509

100

0.887
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.757

99.755

0.566

Multiple sequence alignment