Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   H1X63_RS01775 Genome accession   NZ_LR822027
Coordinates   324933..326450 (+) Length   505 a.a.
NCBI ID   WP_180487783.1    Uniprot ID   A0A8D6U5M9
Organism   Streptococcus thermophilus isolate STH_CIRM_998     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 319933..331450
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1X63_RS10430 (STHERMO_0331) - 320211..320362 (+) 152 Protein_291 ascorbate 6-phosphate lactonase -
  H1X63_RS01750 (STHERMO_0332) - 320400..321071 (-) 672 WP_100284858.1 potassium channel family protein -
  H1X63_RS01755 (STHERMO_0333) - 321111..322475 (-) 1365 WP_269473099.1 TrkH family potassium uptake protein -
  H1X63_RS01760 (STHERMO_0334) rsmG 322545..323258 (-) 714 WP_100284860.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  H1X63_RS01765 (STHERMO_0335) - 323555..324091 (+) 537 WP_180487782.1 DUF177 domain-containing protein -
  H1X63_RS01770 (STHERMO_0336) covR 324247..324936 (+) 690 WP_002949638.1 response regulator transcription factor Regulator
  H1X63_RS01775 (STHERMO_0337) covS 324933..326450 (+) 1518 WP_180487783.1 HAMP domain-containing histidine kinase Regulator
  H1X63_RS01780 (STHERMO_0338) nrdR 326572..327051 (+) 480 WP_179972620.1 transcriptional regulator NrdR -
  H1X63_RS01785 (STHERMO_0339) - 327048..328223 (+) 1176 WP_179972621.1 DnaD domain protein -
  H1X63_RS01790 (STHERMO_0340) dnaI 328227..329129 (+) 903 WP_100284865.1 primosomal protein DnaI -
  H1X63_RS01795 (STHERMO_0341) der 329235..330545 (+) 1311 WP_100284866.1 ribosome biogenesis GTPase Der -
  H1X63_RS01800 - 330609..331277 (+) 669 Protein_302 HI_0552 family protein -

Sequence

Protein


Download         Length: 505 a.a.        Molecular weight: 57567.06 Da        Isoelectric Point: 5.3777

>NTDB_id=1131328 H1X63_RS01775 WP_180487783.1 324933..326450(+) (covS) [Streptococcus thermophilus isolate STH_CIRM_998]
MSKLFGKVTIRKKLTMTTAVVFFLVLSMFTLVVVFSANTLLLQRERQNVNNTISKVVTYIEKDWDSDEELSPEPLLAALY
SPKNIYPSIINGVLSEKRSLDCQVAVSNRLYSNQSVYVYDKKGTFIFTSEEDTDSPPGMSEVNKLKLVSYKGKRGFLLQV
PIYGKDKKTIVGYAQVFHDLKFYYALKERLIFLLIFLEVGMTVLVIAVTIVVLTSILRPMRQLHETMGIIIDSPSDLELR
SKIGSHDEIGALALNFNCMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHEANRM
TIMINDMLDSIRVKGSFDNHRNDTCDLNSSIRTVIGNFRVLHDDYQFYLNDSESLDRPAQIYSQHFEQVITILIDNAVKY
SPVNKEIQITIKALEDEMLVQVQDNGEGISKEDIEHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCHIDVSSE
LGVGTRFDLYIPFADSETTTPQLEG

Nucleotide


Download         Length: 1518 bp        

>NTDB_id=1131328 H1X63_RS01775 WP_180487783.1 324933..326450(+) (covS) [Streptococcus thermophilus isolate STH_CIRM_998]
ATGAGTAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTTTCTTGTATTGTC
GATGTTCACTCTGGTTGTTGTATTTTCAGCCAATACGCTTCTTTTGCAACGTGAACGTCAAAATGTAAATAATACAATCT
CAAAAGTTGTTACTTATATCGAAAAGGACTGGGACTCTGATGAAGAGTTGAGTCCAGAGCCGCTTTTAGCGGCCCTTTAT
TCACCGAAAAATATCTATCCATCAATCATTAATGGAGTGCTTTCTGAAAAGCGTTCCTTAGATTGTCAAGTTGCGGTTTC
TAATAGATTATATTCCAACCAGTCTGTCTATGTTTATGACAAAAAGGGAACTTTTATCTTTACTTCTGAGGAGGATACAG
ACTCACCTCCAGGCATGTCTGAGGTCAATAAACTGAAGTTGGTTTCCTATAAAGGTAAACGTGGTTTCTTACTACAAGTT
CCAATCTATGGCAAGGATAAGAAGACCATTGTTGGGTATGCTCAAGTTTTCCATGATTTGAAATTCTACTATGCGTTAAA
AGAGCGTTTAATTTTCCTATTGATATTCCTTGAAGTAGGAATGACGGTCTTAGTTATTGCAGTAACTATAGTTGTTTTGA
CATCTATTCTTCGTCCGATGAGGCAGTTACACGAAACGATGGGTATTATTATCGATTCGCCAAGTGATTTGGAGCTTCGA
TCTAAGATTGGGAGTCATGATGAGATTGGTGCTTTGGCGCTTAACTTTAACTGTATGATGGATAAAATTCAAGAAAATAA
TCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCACGAATTACGTACTCCTATTGCAGTTATTAAGGGACATATGGACC
TCTTGCAACGTTGGGGTAAAAATGATCCTGAAATCCTTGAAGAAAGTCTTGAAGCTGCAAGTCACGAAGCCAACCGTATG
ACGATTATGATTAACGATATGTTGGATTCTATTCGTGTTAAAGGGTCATTTGACAATCATAGAAATGATACATGTGATTT
GAATTCTTCAATCCGTACGGTTATTGGGAATTTCCGTGTCCTACATGACGACTACCAATTCTACCTCAATGATTCTGAGA
GTTTAGATCGTCCAGCACAGATTTACAGCCAGCACTTTGAACAGGTTATTACTATTTTGATTGATAATGCGGTCAAGTAT
TCGCCTGTTAATAAGGAAATCCAGATTACTATCAAGGCTCTGGAAGATGAGATGCTGGTACAGGTACAGGATAATGGTGA
GGGTATCTCTAAAGAAGATATTGAACATATCTTTGAACGCTTCTATCGTTCAGATAAGGCGCGTAATCGTACGACAACCC
AATCTGGTGTGGGTATTGGTTTATCAATCCTCTATCAAATTGTGGAAGCTTATCGATGCCATATCGATGTCAGTTCAGAA
CTTGGTGTGGGTACACGTTTTGACCTCTACATTCCTTTTGCAGACTCAGAAACTACGACACCTCAACTTGAAGGTTAA

Domains

Predicted by InterproScan.

ArlS sensor domain (ArlS_N)

(39-187)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(384-493)

HAMP domain (HAMP)

(213-265)

His Kinase A (phospho-acceptor) domain (HisKA)

(270-329)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

94.422

99.406

0.939

Multiple sequence alignment