Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   H1X08_RS06925 Genome accession   NZ_LR822025
Coordinates   1343627..1344853 (-) Length   408 a.a.
NCBI ID   WP_179972768.1    Uniprot ID   A0A7U7H3C4
Organism   Streptococcus thermophilus isolate STH_CIRM_961     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1338627..1349853
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1X08_RS06895 (STHERMO_1581) plsY 1338993..1339634 (+) 642 WP_179972771.1 glycerol-3-phosphate 1-O-acyltransferase PlsY -
  H1X08_RS06900 (STHERMO_1582) - 1339752..1340111 (-) 360 WP_002950165.1 helix-hairpin-helix domain-containing protein -
  H1X08_RS06905 (STHERMO_1583) - 1340183..1340437 (-) 255 WP_002950164.1 DUF1912 family protein -
  H1X08_RS06910 (STHERMO_1584) mmuM 1340550..1341500 (-) 951 WP_180482147.1 homocysteine S-methyltransferase -
  H1X08_RS06915 (STHERMO_1585) - 1341512..1342888 (-) 1377 WP_179972769.1 amino acid permease -
  H1X08_RS06920 (STHERMO_1586) yihA 1343018..1343617 (-) 600 WP_002950154.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  H1X08_RS06925 (STHERMO_1587) clpX 1343627..1344853 (-) 1227 WP_179972768.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  H1X08_RS06930 (STHERMO_1588) - 1344871..1345041 (-) 171 WP_002886174.1 hypothetical protein -
  H1X08_RS06935 (STHERMO_1589) - 1345046..1345549 (-) 504 WP_084825846.1 dihydrofolate reductase -
  H1X08_RS06940 (STHERMO_1590) - 1345657..1346517 (-) 861 WP_179972767.1 thymidylate synthase -
  H1X08_RS06945 (STHERMO_1591) - 1346839..1348014 (+) 1176 WP_011680902.1 hydroxymethylglutaryl-CoA synthase -
  H1X08_RS06950 (STHERMO_1592) - 1348007..1349278 (+) 1272 WP_179972766.1 hydroxymethylglutaryl-CoA reductase, degradative -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45030.41 Da        Isoelectric Point: 4.4119

>NTDB_id=1131219 H1X08_RS06925 WP_179972768.1 1343627..1344853(-) (clpX) [Streptococcus thermophilus isolate STH_CIRM_961]
MAGNRNEEMVYCSFCGKNQEEVKKIIAGNGVFICNECVALSQEIIREETAEEVLADLAETPKPKELLDILNNYVVGQDRV
KRALAVAVYNHYKRINFTESREDNDVDLQKSNILLIGPTGSGKTYLAQTLARSLNVPFAIADATSLTEAGYVGEDVENIL
LKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKN
ILFIVGGAFDGIEDIVKQRLGEKIIGFGQNNKAIDDESSYMKEIVAEDIQKFGLIPEFIGRLPVLAALEQLTVDDLVRIL
TEPRNALVKQYQTLLSYDGVELEFDQDALEAIASKAIERKTGARGLRSIIEEVMMDVMFEIPSQEDVTKVRITKEAVDGK
AAPVLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=1131219 H1X08_RS06925 WP_179972768.1 1343627..1344853(-) (clpX) [Streptococcus thermophilus isolate STH_CIRM_961]
ATGGCTGGAAATCGTAATGAAGAGATGGTTTATTGTTCATTTTGTGGCAAAAACCAAGAAGAAGTGAAGAAAATTATCGC
CGGTAATGGCGTCTTTATCTGTAACGAATGTGTGGCCTTGTCACAAGAAATCATTCGTGAGGAAACGGCTGAAGAAGTTT
TAGCTGACTTGGCTGAAACGCCAAAGCCAAAAGAACTTTTAGATATTTTGAACAACTATGTCGTGGGGCAAGATCGTGTC
AAACGTGCCTTGGCAGTAGCTGTTTACAACCACTATAAACGTATCAACTTCACAGAAAGTCGTGAAGATAATGATGTGGA
CTTGCAAAAATCAAATATCCTCTTGATTGGACCAACAGGGTCAGGGAAAACTTACTTAGCTCAGACTTTGGCTCGTAGTT
TGAATGTTCCTTTCGCGATTGCGGATGCGACATCATTGACAGAGGCAGGTTATGTGGGTGAGGATGTGGAAAATATCCTC
CTCAAACTAATCCAAGCGGCAGACTTTAATATTGAACGTGCGGAACGTGGGATTATCTACGTGGACGAGATTGATAAGAT
TGCCAAAAAAGGTGAGAATGTTTCAATCACTCGTGATGTTTCAGGTGAAGGGGTTCAACAAGCTCTCTTGAAGATTATTG
AGGGAACAGTGGCTAGTGTTCCACCTCAAGGTGGTCGTAAACACCCTAATCAAGAGATGATTCAAATTGATACTAAGAAT
ATTCTCTTTATCGTGGGTGGTGCTTTTGATGGTATCGAAGATATCGTTAAGCAACGTCTTGGTGAGAAAATCATTGGGTT
TGGTCAAAATAATAAAGCAATTGATGACGAATCATCATACATGAAAGAAATTGTGGCTGAAGATATCCAAAAATTTGGAC
TTATCCCTGAATTTATCGGACGTTTGCCAGTTCTTGCGGCCCTTGAACAGTTAACGGTTGACGACTTGGTGCGTATTTTG
ACAGAGCCTAGGAATGCCTTGGTGAAGCAGTATCAAACCCTCTTGTCTTATGATGGGGTTGAACTTGAGTTTGACCAGGA
TGCCCTTGAGGCTATTGCAAGTAAGGCAATTGAACGTAAGACTGGTGCGCGTGGGCTTCGCTCTATCATTGAAGAAGTCA
TGATGGATGTTATGTTTGAAATCCCTAGTCAGGAAGATGTCACTAAGGTTCGTATCACCAAAGAAGCTGTTGATGGGAAA
GCTGCTCCAGTATTGGAAACAGCATAA

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7H3C4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

88.753

100

0.89
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.002

99.755

0.569

Multiple sequence alignment