Detailed information NTG1131128

Bioinformatically predicted

Overview

• Name: oppD
• Type: Regulator
• Locus tag: H0513_RS01240
• Genome accession: NZ_LR822023
• Coordinates: 215587..216624 (+)
• Length: 345 a.a.
• NCBI ID: WP_232086215.1
• Uniprot ID: A0A7U7C721
• Organism: Streptococcus thermophilus isolate STH_CIRM_368
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 210587..221624

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H0513_RS01225 (STHERMO_0232)	-	211836..213483 (+)	1648	Protein_189	peptide ABC transporter substrate-binding protein	-
H0513_RS01230 (STHERMO_0233)	-	213614..214528 (+)	915	WP_179972557.1	ABC transporter permease	-
H0513_RS01235 (STHERMO_0234)	-	214539..215570 (+)	1032	WP_258380588.1	ABC transporter permease	-
H0513_RS01240 (STHERMO_0235)	oppD	215587..216624 (+)	1038	WP_232086215.1	ABC transporter ATP-binding protein	Regulator
H0513_RS01245 (STHERMO_0236)	amiF	216626..217564 (+)	939	WP_100262323.1	ABC transporter ATP-binding protein	Regulator
H0513_RS10750 (STHERMO_0237)	-	217678..217839 (+)	162	WP_232086214.1	hypothetical protein	-
H0513_RS01255 (STHERMO_0238)	hslO	218114..218980 (+)	867	WP_100262322.1	Hsp33 family molecular chaperone HslO	-
H0513_RS01260 (STHERMO_0239)	dusB	218973..219950 (+)	978	WP_179972558.1	tRNA dihydrouridine synthase DusB	-
H0513_RS01265 (STHERMO_0240)	-	220153..221016 (+)	864	WP_011226821.1	Rgg/GadR/MutR family transcriptional regulator	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 38503.48 Da
• Isoelectric Point: 5.4595

>NTDB_id=1131128 H0513_RS01240 WP_232086215.1 215587..216624(+) (oppD) [Streptococcus thermophilus isolate STH_CIRM_368]
MKETVLSVKNLHVNFHTYAGEVKAIRDVNFDLKKGETLAIVGESGSGKSVMTRTLMGLSEKNAKVTGDITFKGRDMQALR
EEDWVKVRGNDIAMIFQDPMTSLDPTMKIGLQIAEPIMIHTKVSKKEALDMALQLMKDVGIPNAEEHINDYPHQWSGGMR
QRAVIAIALAADPEILIADEPTTALDVTIQAQILRLMKKIQEERDSSIIFITHDLGVVAGMADRVAVMYAGKILEYGTVD
EVFYNPQHPYTWGLLNSMPTIETESGSLEAIPGTPPDLLYPPKGDAFAPRNVFALAIDYQEEPPMFKVSDTHFAATWLLD
ERAPKVTPPSPILKRWEKWSKMKEK

Nucleotide

• Length: 1038 bp

>NTDB_id=1131128 H0513_RS01240 WP_232086215.1 215587..216624(+) (oppD) [Streptococcus thermophilus isolate STH_CIRM_368]
ATGAAAGAAACGGTTTTAAGTGTAAAAAATCTCCATGTTAATTTTCATACTTACGCTGGAGAAGTAAAAGCGATTCGTGA
TGTCAATTTTGACTTGAAAAAAGGTGAGACACTGGCAATTGTTGGTGAGTCTGGCTCAGGAAAATCTGTAATGACAAGGA
CATTAATGGGTCTATCAGAGAAAAACGCTAAGGTAACTGGAGACATTACCTTTAAAGGGCGCGATATGCAAGCCTTGAGG
GAGGAAGATTGGGTCAAGGTCCGTGGAAATGATATTGCTATGATTTTTCAAGATCCTATGACCAGTCTTGACCCTACTAT
GAAAATTGGGCTCCAAATTGCTGAGCCTATTATGATTCATACCAAAGTATCTAAGAAAGAAGCTTTAGATATGGCTTTAC
AATTAATGAAAGATGTTGGGATACCTAATGCCGAAGAACATATAAATGACTACCCTCACCAATGGTCAGGAGGAATGCGT
CAAAGAGCAGTAATTGCCATTGCTCTAGCTGCAGATCCTGAAATTTTGATTGCTGACGAGCCTACTACAGCTTTAGATGT
TACGATTCAAGCACAAATTCTTCGTCTGATGAAAAAAATCCAAGAAGAGCGTGATTCATCCATTATTTTTATTACTCATG
ACTTGGGTGTTGTCGCTGGGATGGCTGATCGTGTAGCGGTTATGTATGCTGGCAAAATTTTGGAATATGGGACTGTGGAT
GAGGTTTTCTATAATCCGCAACACCCATACACATGGGGACTTCTTAACTCTATGCCTACAATAGAAACAGAATCTGGCAG
CCTAGAAGCTATTCCAGGAACTCCTCCAGATTTGCTTTATCCTCCTAAAGGTGATGCCTTTGCTCCTCGAAATGTCTTTG
CTTTAGCTATTGATTATCAGGAAGAACCGCCAATGTTTAAAGTATCAGATACGCATTTTGCAGCAACATGGCTCTTAGAT
GAACGAGCTCCTAAAGTAACCCCTCCTTCGCCAATATTGAAACGATGGGAAAAATGGTCAAAGATGAAGGAGAAATAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (26-182)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (234-295)

3D structure

• AlphaFold DB: A0A7U7C721

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
oppD	Streptococcus mutans UA159	80.702	99.13	0.8
amiE	Streptococcus salivarius strain HSISS4	56.932	98.261	0.559
amiE	Streptococcus thermophilus LMG 18311	56.342	98.261	0.554
amiE	Streptococcus thermophilus LMD-9	56.342	98.261	0.554