Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   H0511_RS03025 Genome accession   NZ_LR822017
Coordinates   571233..572459 (+) Length   408 a.a.
NCBI ID   WP_084825847.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_336     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 566233..577459
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0511_RS03000 (STHERMO_0634) - 566808..568079 (-) 1272 WP_179974342.1 hydroxymethylglutaryl-CoA reductase, degradative -
  H0511_RS03005 (STHERMO_0635) - 568072..569247 (-) 1176 WP_011680902.1 hydroxymethylglutaryl-CoA synthase -
  H0511_RS03010 (STHERMO_0636) - 569569..570429 (+) 861 WP_179974343.1 thymidylate synthase -
  H0511_RS03015 (STHERMO_0637) - 570537..571040 (+) 504 WP_084825846.1 dihydrofolate reductase -
  H0511_RS03020 (STHERMO_0638) - 571045..571215 (+) 171 WP_002886174.1 hypothetical protein -
  H0511_RS03025 (STHERMO_0639) clpX 571233..572459 (+) 1227 WP_084825847.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  H0511_RS03030 (STHERMO_0640) yihA 572469..573068 (+) 600 WP_179974344.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  H0511_RS03035 (STHERMO_0641) - 573198..574574 (+) 1377 WP_179974345.1 amino acid permease -
  H0511_RS03040 (STHERMO_0642) mmuM 574586..575536 (+) 951 WP_084825850.1 homocysteine S-methyltransferase -
  H0511_RS03045 (STHERMO_0643) - 575649..575903 (+) 255 WP_002950164.1 DUF1912 family protein -
  H0511_RS03050 (STHERMO_0644) - 575975..576334 (+) 360 WP_002950165.1 helix-hairpin-helix domain-containing protein -
  H0511_RS03055 (STHERMO_0645) plsY 576448..577089 (-) 642 WP_179974346.1 glycerol-3-phosphate 1-O-acyltransferase PlsY -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45015.43 Da        Isoelectric Point: 4.4119

>NTDB_id=1130962 H0511_RS03025 WP_084825847.1 571233..572459(+) (clpX) [Streptococcus thermophilus isolate STH_CIRM_336]
MAGNRNEEMVYCSFCGKNQEEVKKIIAGNGVFICNECVALSQEIIREETAEEVLADLAETPKPKELLDILNNYVVGQDRV
KRALAVAVYNHYKRINFTESREDNDVDLQKSNILLIGPTGSGKTYLAQTLARSLNVPFAIADATSLTEAGYVGEDVENIL
LKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKN
ILFIVGGAFDGIEDIVKQRLGEKIIGFGQNNKAIDDESSYMKEIVAEDIQKFGLIPEFIGRLPVLAALEQLTVDDLVRIL
TEPRNALVKQYQTLLSYDGVELEFDQDALEAIASKAIERKTGARGLRSIIEEVMMDVMFEIPSLEDVTKVRITKEAVDGK
AAPVLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=1130962 H0511_RS03025 WP_084825847.1 571233..572459(+) (clpX) [Streptococcus thermophilus isolate STH_CIRM_336]
ATGGCTGGAAATCGTAATGAAGAGATGGTTTATTGTTCATTTTGTGGCAAAAACCAAGAAGAAGTGAAGAAAATTATCGC
CGGTAATGGCGTCTTTATCTGTAACGAATGTGTGGCCTTGTCACAAGAAATCATTCGTGAGGAAACGGCTGAAGAAGTTT
TAGCTGACTTGGCTGAAACGCCAAAGCCAAAAGAACTTTTAGATATTTTGAACAACTATGTCGTGGGGCAAGATCGTGTC
AAACGTGCCTTGGCAGTAGCTGTTTACAACCACTATAAACGTATCAACTTCACAGAAAGTCGTGAAGATAATGATGTGGA
CTTGCAAAAATCAAATATCCTCTTGATTGGACCAACAGGGTCAGGGAAAACTTACTTAGCTCAGACTTTGGCTCGTAGTT
TGAATGTTCCTTTCGCGATTGCGGATGCGACATCATTGACAGAGGCAGGTTATGTGGGTGAGGATGTGGAAAATATCCTC
CTCAAACTAATCCAAGCGGCAGACTTTAATATTGAACGTGCGGAACGTGGGATTATCTACGTGGACGAGATTGATAAGAT
TGCCAAAAAAGGTGAGAATGTTTCAATCACTCGTGATGTTTCAGGTGAAGGGGTTCAACAAGCTCTCTTGAAGATTATTG
AGGGAACAGTGGCTAGTGTTCCACCTCAAGGTGGTCGTAAACACCCTAATCAAGAGATGATTCAAATTGATACTAAGAAT
ATTCTCTTTATCGTGGGTGGTGCTTTTGATGGTATCGAAGATATCGTTAAGCAACGTCTTGGTGAGAAAATCATTGGGTT
TGGTCAAAATAATAAAGCAATTGATGACGAATCATCATACATGAAAGAAATTGTGGCTGAAGATATCCAAAAATTTGGAC
TTATCCCTGAATTTATCGGACGTTTGCCAGTTCTTGCGGCCCTTGAACAGTTAACGGTTGACGACTTGGTGCGTATTTTG
ACAGAGCCTAGGAATGCCTTGGTGAAGCAGTATCAAACCCTCTTGTCTTATGATGGGGTTGAACTTGAGTTTGACCAGGA
TGCCCTTGAGGCTATTGCAAGTAAGGCAATTGAACGTAAGACTGGTGCGCGTGGGCTTCGCTCTATCATTGAAGAAGTCA
TGATGGATGTTATGTTTGAAATCCCTAGTCTGGAAGATGTCACTAAGGTTCGTATCACCAAAGAAGCTGTTGATGGGAAA
GCTGCTCCAGTATTGGAAACAGCATAA

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-388)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

88.509

100

0.887
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.002

99.755

0.569

Multiple sequence alignment