Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   H0511_RS01920 Genome accession   NZ_LR822017
Coordinates   357775..359073 (+) Length   432 a.a.
NCBI ID   WP_179974253.1    Uniprot ID   A0A8D6U1G7
Organism   Streptococcus thermophilus isolate STH_CIRM_336     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 352775..364073
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0511_RS01895 (STHERMO_0384) - 353707..354471 (+) 765 WP_002949740.1 ABC transporter ATP-binding protein -
  H0511_RS01900 (STHERMO_0385) - 354471..355181 (+) 711 WP_014607989.1 ABC transporter ATP-binding protein -
  H0511_RS01905 (STHERMO_0386) - 355317..355947 (+) 631 Protein_330 CBS domain-containing protein -
  H0511_RS01910 (STHERMO_0388) cysK 356065..356991 (-) 927 WP_179974252.1 cysteine synthase A -
  H0511_RS01915 (STHERMO_0389) - 357093..357719 (-) 627 WP_011225515.1 YigZ family protein -
  H0511_RS01920 (STHERMO_0390) comFA/cflA 357775..359073 (+) 1299 WP_179974253.1 DEAD/DEAH box helicase Machinery gene
  H0511_RS01925 (STHERMO_0391) - 359076..359738 (+) 663 WP_179974254.1 ComF family protein -
  H0511_RS01930 (STHERMO_0392) hpf 359817..360374 (+) 558 WP_179974255.1 ribosome hibernation-promoting factor, HPF/YfiA family -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49992.18 Da        Isoelectric Point: 9.9677

>NTDB_id=1130956 H0511_RS01920 WP_179974253.1 357775..359073(+) (comFA/cflA) [Streptococcus thermophilus isolate STH_CIRM_336]
MIPKEYYGRLFTKEQLPVDYLSEAVKLESMIKVDKKLRCKRCYSRIEEDWQLPNGQYYCRACIVFGRNQEGKELYYFPSE
KSEVDFPVLKWSGKLTPYQNEVSEKLLKTYKNQKHSLVHAVTGAGKTEMIYNIVAYVLENKNRVVIASPRVDVCRELFLR
MQKDFTCSISLLHADSEPYDGSPLVIATTHQLLKFYHSFDLIIVDEVDAFPFVGNVMLNHAVKQAKTETGRYIYLTATST
LALEEQVRLGAIEKHHLASRFHGNPLVLPRFFWQGRLQKSLTNEKLPRSLIHQIKKQRKSNFPLLIFFPNIALGEKFSIT
LKKYLPTENIAFVSSKSEERSTIVEKFRKKELSILVTTTILERGVTFPQVDVFVCMANHHLYTSSSLIQIGGRVGRSPER
PTGKLYFFHEGLSKSMLQCRKEIKAMNKKRRV

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=1130956 H0511_RS01920 WP_179974253.1 357775..359073(+) (comFA/cflA) [Streptococcus thermophilus isolate STH_CIRM_336]
ATGATACCTAAAGAATATTATGGACGACTATTTACGAAAGAACAGTTACCAGTGGACTATCTCTCAGAGGCTGTAAAATT
AGAAAGTATGATAAAGGTTGATAAAAAACTTAGATGTAAAAGATGTTATAGTCGAATAGAGGAAGATTGGCAATTACCGA
ATGGTCAGTATTATTGTAGAGCGTGTATTGTCTTTGGTCGAAACCAAGAAGGAAAAGAACTCTATTACTTTCCCTCAGAA
AAATCAGAAGTAGATTTTCCTGTCTTGAAATGGTCAGGAAAACTGACTCCTTATCAAAATGAGGTCTCGGAAAAGCTTTT
AAAGACTTATAAAAATCAAAAACACAGTCTTGTTCATGCAGTGACTGGTGCTGGCAAGACAGAGATGATTTATAATATTG
TTGCCTATGTTCTTGAAAATAAAAATCGTGTTGTCATCGCAAGTCCCCGAGTTGATGTTTGTCGAGAATTGTTTCTACGC
ATGCAGAAAGATTTTACTTGTAGTATTTCTCTGCTTCATGCTGATAGTGAACCATATGATGGTAGTCCGCTCGTTATAGC
TACCACTCATCAATTACTAAAATTTTATCATAGCTTTGACTTGATTATTGTTGATGAAGTTGATGCCTTTCCATTTGTAG
GGAATGTCATGTTAAATCATGCTGTTAAACAGGCAAAGACGGAAACAGGCCGGTATATTTACTTAACAGCAACTTCTACA
TTAGCTTTAGAAGAGCAAGTGCGCCTTGGAGCTATAGAAAAGCATCACCTTGCTAGTCGTTTCCACGGAAATCCTTTAGT
CCTTCCTCGTTTCTTTTGGCAAGGAAGGTTACAAAAGTCGTTGACGAACGAGAAGCTTCCAAGGTCTCTAATTCACCAGA
TTAAGAAGCAGCGTAAATCAAATTTTCCTCTATTAATCTTTTTCCCCAATATAGCATTAGGTGAAAAGTTTAGTATTACC
CTAAAAAAATATCTCCCTACTGAAAACATAGCCTTTGTTTCATCAAAAAGCGAGGAGCGTTCAACCATCGTAGAGAAATT
CCGAAAAAAAGAATTGTCAATCTTAGTGACGACAACTATTCTCGAACGTGGTGTTACCTTTCCACAAGTAGATGTTTTTG
TTTGTATGGCAAATCATCACTTATATACTAGTTCGAGTCTTATTCAGATTGGTGGTAGGGTGGGGCGTTCGCCCGAGAGA
CCTACAGGGAAACTCTATTTCTTTCATGAAGGATTATCTAAGTCAATGTTGCAATGTCGGAAAGAAATAAAAGCAATGAA
TAAAAAAAGGAGGGTTTGA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(290-396)

Type III restriction enzyme, res subunit (ResIII)

(94-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

55.374

99.074

0.549
  comFA/cflA Streptococcus pneumoniae D39

55.374

99.074

0.549
  comFA/cflA Streptococcus pneumoniae R6

55.374

99.074

0.549
  comFA/cflA Streptococcus pneumoniae TIGR4

55.374

99.074

0.549
  comFA/cflA Streptococcus mitis NCTC 12261

55.035

98.843

0.544
  comFA/cflA Streptococcus mitis SK321

54.098

98.843

0.535
  comFA Lactococcus lactis subsp. cremoris KW2

45.913

96.296

0.442
  comFA Latilactobacillus sakei subsp. sakei 23K

37.156

100

0.375

Multiple sequence alignment