Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   H0506_RS05305 Genome accession   NZ_LR822015
Coordinates   1007656..1008996 (-) Length   446 a.a.
NCBI ID   WP_011226083.1    Uniprot ID   A0A060BIR3
Organism   Streptococcus thermophilus isolate STH_CIRM_65     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1002656..1013996
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0506_RS05275 (STHERMO_1166) - 1002774..1003160 (-) 387 WP_002953113.1 DUF1934 domain-containing protein -
  H0506_RS05280 - 1003252..1004132 (-) 881 Protein_974 GNAT family N-acetyltransferase -
  H0506_RS05285 (STHERMO_1170) yidA 1004340..1005149 (+) 810 WP_011226081.1 sugar-phosphatase -
  H0506_RS05290 (STHERMO_1171) - 1005151..1006365 (+) 1215 WP_179971674.1 aminoacyltransferase -
  H0506_RS05295 - 1006417..1006778 (-) 362 Protein_977 YbaN family protein -
  H0506_RS05300 (STHERMO_1172) vicX 1006838..1007650 (-) 813 WP_011681204.1 MBL fold metallo-hydrolase Regulator
  H0506_RS05305 (STHERMO_1173) vicK 1007656..1008996 (-) 1341 WP_011226083.1 cell wall metabolism sensor histidine kinase VicK Regulator
  H0506_RS05310 (STHERMO_1174) vicR 1008989..1009696 (-) 708 WP_011227274.1 response regulator YycF Regulator
  H0506_RS05315 (STHERMO_1176) - 1010228..1010995 (+) 768 WP_011227275.1 amino acid ABC transporter ATP-binding protein -
  H0506_RS05320 (STHERMO_1177) - 1011007..1011840 (+) 834 WP_011227276.1 transporter substrate-binding domain-containing protein -
  H0506_RS05325 (STHERMO_1178) - 1011858..1012556 (+) 699 WP_011226087.1 amino acid ABC transporter permease -
  H0506_RS05330 (STHERMO_1179) - 1012568..1013218 (+) 651 WP_011226088.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 50782.15 Da        Isoelectric Point: 5.2464

>NTDB_id=1130910 H0506_RS05305 WP_011226083.1 1007656..1008996(-) (vicK) [Streptococcus thermophilus isolate STH_CIRM_65]
MTSIGLNITSFELALLFMLLFVAFYFIFLAYRDYQQVKNIRKLTKRVKSLMAGNYNEKLCIKGDSELLELANSLNDLSDV
FRLTHENLIQEKNRLSSVLSYMSDGVIATNRLGQITMINSTAQRLLNLDRETATQMSILDILDGENPYTYSELLSKTPEI
HLSRRDANDEFVTLRVNFALIRKESGFISGLVAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALNE
EIAPNFIKVSLDETNRMMRMITDLLALSRIDNKSTQLNVEMTNFTAFMTYILNRFGQIKSQETNPGKSYEIIRDYPVNSI
WVEIDTDKMTQVIDNILNNAIKYSPDGGKITVSMKTTDTQLIVSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLSIAKEIVKQHNGFIWAKSEYGKGSTFTIVLPYDQDAMMVDEWEM

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=1130910 H0506_RS05305 WP_011226083.1 1007656..1008996(-) (vicK) [Streptococcus thermophilus isolate STH_CIRM_65]
ATGACTAGTATTGGCTTAAATATTACAAGCTTTGAACTGGCCTTACTCTTTATGCTCCTCTTTGTTGCTTTCTATTTCAT
TTTTCTAGCTTATCGTGATTATCAACAGGTCAAAAATATCCGAAAGTTGACTAAGAGAGTCAAATCCCTTATGGCAGGTA
ATTATAATGAAAAATTATGCATAAAGGGAGATTCAGAGCTTTTAGAGCTAGCTAATAGCTTGAATGATTTGTCGGACGTC
TTTCGTTTGACACATGAAAATCTAATCCAGGAAAAAAACCGCTTATCATCTGTTCTTTCGTACATGAGTGACGGGGTTAT
TGCGACCAATCGCCTTGGTCAGATTACTATGATTAATAGTACTGCCCAACGCTTGTTGAATTTAGATCGCGAAACTGCGA
CTCAGATGTCTATTTTGGATATATTAGATGGTGAGAATCCCTATACCTATAGTGAATTGTTGTCTAAGACACCCGAAATC
CATCTGTCGCGTCGAGATGCTAACGATGAATTTGTGACGCTACGTGTTAATTTTGCATTAATTCGTAAGGAATCTGGTTT
TATTTCAGGTCTGGTAGCCGTTCTTCATGATGCCACTGAGCAGGAAAAAGAAGAGCGCGAACGCCGTCTCTTCGTATCAA
ATGTTAGTCACGAATTGCGGACGCCTTTAACTTCTGTGAAATCCTATCTTGAAGCGCTTGATGATGGTGCTCTCAACGAA
GAGATTGCTCCAAACTTTATCAAAGTTTCTTTAGATGAAACCAACCGCATGATGCGTATGATTACTGACCTCTTGGCATT
ATCTCGAATTGACAATAAAAGCACACAGCTTAATGTTGAAATGACAAACTTTACAGCCTTTATGACCTATATCTTGAATC
GGTTTGGTCAAATTAAGAGTCAAGAAACTAATCCAGGTAAGTCTTATGAAATCATTCGAGATTACCCAGTAAACTCTATT
TGGGTGGAAATTGATACTGATAAGATGACCCAGGTCATAGATAATATACTTAATAATGCCATCAAGTATTCTCCTGATGG
TGGGAAAATTACAGTATCTATGAAAACGACAGACACTCAGTTGATTGTTTCTATTTCTGACCAAGGTTTAGGAATTCCTA
AAAAAGATTTACCTCTGATTTTTGACCGTTTTTACCGTGTTGATAAGGCTAGAAGTCGTGCTCAGGGTGGAACAGGACTT
GGCTTATCCATTGCAAAAGAAATTGTTAAACAACATAATGGCTTCATTTGGGCTAAGAGTGAGTATGGTAAGGGATCAAC
TTTTACAATTGTGCTTCCATATGACCAGGACGCAATGATGGTCGATGAATGGGAGATGTAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)

HAMP domain (HAMP)

(37-79)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)

PAS fold (PAS)

(94-197)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A060BIR3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

74.638

92.825

0.693
  micB Streptococcus pneumoniae Cp1015

66.282

97.085

0.644

Multiple sequence alignment