Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   H0502_RS02965 Genome accession   NZ_LR822013
Coordinates   594310..595650 (+) Length   446 a.a.
NCBI ID   WP_084830671.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_32     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 589310..600650
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0502_RS02940 (STHERMO_0676) - 590093..590743 (-) 651 WP_014608375.1 amino acid ABC transporter permease -
  H0502_RS02945 (STHERMO_0677) - 590755..591453 (-) 699 WP_014608374.1 amino acid ABC transporter permease -
  H0502_RS02950 (STHERMO_0678) - 591471..592304 (-) 834 WP_179970665.1 transporter substrate-binding domain-containing protein -
  H0502_RS02955 (STHERMO_0679) - 592316..593083 (-) 768 WP_011681207.1 amino acid ABC transporter ATP-binding protein -
  H0502_RS02960 (STHERMO_0680) vicR 593610..594317 (+) 708 WP_011681206.1 response regulator YycF Regulator
  H0502_RS02965 (STHERMO_0681) vicK 594310..595650 (+) 1341 WP_084830671.1 cell wall metabolism sensor histidine kinase VicK Regulator
  H0502_RS02970 (STHERMO_0682) vicX 595656..596468 (+) 813 WP_011681204.1 MBL fold metallo-hydrolase Regulator
  H0502_RS02975 (STHERMO_0683) - 596528..596889 (+) 362 Protein_594 YbaN family protein -
  H0502_RS02980 (STHERMO_0684) - 596941..598155 (-) 1215 WP_002953123.1 aminoacyltransferase -
  H0502_RS02985 (STHERMO_0685) yidA 598157..598966 (-) 810 WP_011226081.1 sugar-phosphatase -
  H0502_RS02990 - 599174..600052 (+) 879 Protein_597 GNAT family N-acetyltransferase -
  H0502_RS02995 (STHERMO_0689) - 600144..600530 (+) 387 WP_002953113.1 DUF1934 domain-containing protein -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 50767.14 Da        Isoelectric Point: 5.3880

>NTDB_id=1130781 H0502_RS02965 WP_084830671.1 594310..595650(+) (vicK) [Streptococcus thermophilus isolate STH_CIRM_32]
MTSIGLNITSFELALLFMLLFVAFYFIFLAYRDYQQVKNIRKLTKRVKSLMAGNYNEKLCIKGNSELLELANSLNDLSDV
FRLTHENLIQEKNRLSSVLSYMSDGVIATNRLGQITMINSTAQRLLNLDRETATQMSILDILDGENPYTYSELLSKTPEI
HLSRRDANDEFVTLRVNFALIRKESGFISGLVAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALNE
EIAPNFIKVSLDETNRMMRMISDLLALSRIDNKSTQLNVEMTNFTAFMTYILNRFGQIKSQETNPGKSYEIIRDYPVNSI
WVEIDTDKMTQVIDNILNNAIKYSPDGGKITVSMKTTDTQLIVSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLSIAKEIVKQHNGFIWAKSEYGKGSTFTIVLPYDQDAMMVDEWEM

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=1130781 H0502_RS02965 WP_084830671.1 594310..595650(+) (vicK) [Streptococcus thermophilus isolate STH_CIRM_32]
ATGACTAGTATTGGCTTAAATATTACAAGCTTTGAACTGGCCTTACTCTTTATGCTCCTCTTTGTTGCTTTCTATTTCAT
TTTTCTAGCTTATCGTGATTATCAACAGGTCAAAAATATCCGAAAGTTGACTAAGAGAGTCAAATCCCTTATGGCAGGTA
ATTATAATGAAAAATTATGCATAAAGGGAAATTCAGAGCTTTTAGAGCTAGCTAATAGCTTGAATGATTTGTCGGACGTC
TTTCGTTTGACACATGAAAATCTAATCCAGGAAAAAAACCGCTTATCATCTGTCCTTTCGTACATGAGTGACGGGGTTAT
TGCGACCAATCGCCTTGGTCAGATTACTATGATTAATAGTACTGCCCAACGTTTGTTGAATTTAGATCGCGAAACTGCGA
CTCAGATGTCTATTTTGGATATATTAGATGGTGAGAATCCCTATACCTATAGTGAATTGTTGTCTAAGACACCCGAAATC
CATCTGTCGCGTCGAGATGCTAACGATGAATTTGTGACGCTACGTGTTAATTTTGCATTAATTCGTAAGGAATCTGGTTT
TATTTCAGGTCTGGTAGCCGTTCTTCATGATGCCACTGAGCAGGAAAAAGAAGAGCGCGAACGCCGTCTCTTCGTATCAA
ATGTTAGTCACGAATTGCGGACGCCTTTAACTTCTGTGAAATCCTATCTTGAAGCGCTTGATGATGGTGCTCTCAACGAA
GAGATTGCTCCAAACTTTATCAAAGTTTCTTTAGATGAAACCAACCGCATGATGCGTATGATTTCTGACCTCTTGGCATT
ATCTCGAATTGACAATAAAAGCACACAGCTTAATGTTGAAATGACAAACTTTACAGCCTTTATGACCTATATCTTGAATC
GGTTTGGTCAAATTAAGAGTCAAGAAACTAATCCAGGTAAGTCTTATGAAATCATTCGAGATTACCCAGTAAACTCTATT
TGGGTGGAAATTGATACTGATAAGATGACCCAGGTCATAGATAATATACTTAATAATGCCATCAAGTATTCTCCTGATGG
TGGGAAAATTACAGTATCTATGAAAACGACAGACACTCAGTTGATTGTTTCTATTTCTGACCAAGGTTTAGGAATTCCTA
AAAAAGATTTACCTCTGATTTTTGACCGTTTTTACCGTGTTGATAAGGCCAGAAGTCGTGCTCAGGGTGGAACAGGACTT
GGCTTATCCATTGCAAAAGAAATTGTTAAACAACATAATGGCTTCATTTGGGCTAAGAGTGAGTATGGTAAGGGATCAAC
TTTTACAATTGTGCTTCCATATGACCAGGACGCAATGATGGTCGATGAATGGGAGATGTAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)

PAS fold (PAS)

(94-197)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)

HAMP domain (HAMP)

(37-79)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

74.638

92.825

0.693
  micB Streptococcus pneumoniae Cp1015

66.051

97.085

0.641

Multiple sequence alignment