Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   H0505_RS01845 Genome accession   NZ_LR822012
Coordinates   342666..343985 (+) Length   439 a.a.
NCBI ID   WP_179971190.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_30     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 337666..348985
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0505_RS01820 (STHERMO_0375) - 338522..339286 (+) 765 WP_002947187.1 ABC transporter ATP-binding protein -
  H0505_RS01825 (STHERMO_0376) - 339286..339996 (+) 711 WP_002947183.1 ABC transporter ATP-binding protein -
  H0505_RS01830 (STHERMO_0377) - 340132..340790 (+) 659 Protein_314 CBS domain-containing protein -
  H0505_RS01835 (STHERMO_0379) cysK 340957..341883 (-) 927 WP_014607992.1 cysteine synthase A -
  H0505_RS01840 (STHERMO_0380) - 341985..342611 (-) 627 WP_002949745.1 YigZ family protein -
  H0505_RS01845 (STHERMO_0381) comFA/cflA 342666..343985 (+) 1320 WP_179971190.1 DEAD/DEAH box helicase Machinery gene
  H0505_RS01850 (STHERMO_0382) - 343966..344628 (+) 663 WP_002949747.1 ComF family protein -
  H0505_RS01855 (STHERMO_0383) hpf 344707..345255 (+) 549 WP_011680772.1 ribosome hibernation-promoting factor, HPF/YfiA family -

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 50601.74 Da        Isoelectric Point: 9.7105

>NTDB_id=1130720 H0505_RS01845 WP_179971190.1 342666..343985(+) (comFA/cflA) [Streptococcus thermophilus isolate STH_CIRM_30]
MIPKEYYGRLFTKEQLPVDYLSEAVKLESMIKVDKKLRCKRCYSRIEEDWQLPNGQYYCRACIVFGRNQEGKELYYFPSE
KSEVDFPVLKWSGKLTPYQNEVSEKLLKTYKNQKHSLVHAVTGAGKTEMIYNIVAYVLENKNRVVIASPRVDVCRELFLR
MQKDFTCSISLLHADSEPYDGSPLVIATTHQLLKFYHSFDLIIVDEVDAFPFVGNVMLNHAVKQAKTETGRYIYLTATST
LALEEQVRLGAIEKHHLASRFHGNPLVLPRFFWQGRLQKSLTSEKLPRPLIHQIKKQRKSNFPLLIFFPNIALGEKFSIT
LKKYLPTENIAFVSSKSEERSTIVEKFRKKELSILVTTTILERGVTFPQVDVFVCMANHHLYTSSSLIQIGGRVGRSPER
PTGKLYFFHEGLSKSMLQCRKEINAMNKKGGFENEVSTM

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=1130720 H0505_RS01845 WP_179971190.1 342666..343985(+) (comFA/cflA) [Streptococcus thermophilus isolate STH_CIRM_30]
ATGATACCTAAAGAATATTATGGACGACTATTTACGAAAGAACAGTTACCAGTGGATTATCTCTCAGAGGCTGTAAAATT
AGAAAGTATGATAAAGGTTGATAAAAAACTTAGATGTAAAAGATGTTATAGTCGAATAGAGGAAGATTGGCAATTACCAA
ATGGTCAGTATTATTGTAGAGCGTGTATTGTCTTTGGTCGAAACCAAGAAGGAAAAGAACTCTATTACTTTCCCTCAGAA
AAATCAGAAGTAGATTTTCCTGTCTTGAAATGGTCAGGAAAACTGACTCCTTATCAAAATGAGGTCTCGGAAAAGCTTTT
AAAGACTTATAAAAATCAAAAACACAGTCTTGTTCATGCAGTGACTGGTGCTGGCAAGACAGAGATGATTTATAATATTG
TTGCCTATGTTCTTGAAAATAAAAATCGTGTCGTCATCGCAAGTCCCCGAGTTGATGTTTGTCGAGAATTGTTTCTACGC
ATGCAGAAAGATTTTACTTGTAGTATTTCTCTGCTTCATGCTGATAGTGAACCATATGATGGTAGTCCGCTCGTTATAGC
TACCACTCATCAATTACTAAAATTTTATCATAGCTTTGACTTGATTATTGTTGACGAAGTTGATGCCTTTCCATTTGTAG
GGAATGTCATGTTAAATCATGCTGTTAAACAGGCAAAGACGGAAACAGGCCGGTATATTTACTTAACAGCAACTTCTACA
TTAGCTTTAGAAGAGCAAGTGCGCCTTGGAGCTATAGAAAAGCATCACCTTGCTAGTCGTTTCCACGGAAATCCTTTAGT
CCTTCCTCGTTTCTTTTGGCAAGGAAGGTTACAAAAGTCGTTGACGAGCGAGAAGCTTCCAAGGCCTCTAATTCACCAGA
TTAAGAAGCAGCGTAAATCAAATTTTCCTCTATTAATCTTTTTCCCCAATATAGCATTAGGTGAAAAGTTTAGTATTACC
CTAAAAAAATATCTCCCTACTGAAAACATAGCCTTTGTTTCATCAAAAAGCGAGGAGCGTTCAACCATTGTTGAGAAATT
CCGAAAAAAAGAATTGTCAATCTTAGTGACGACAACTATTCTCGAACGTGGTGTTACCTTTCCACAAGTAGATGTTTTTG
TTTGTATGGCAAATCATCACTTATATACTAGTTCGAGTCTTATTCAGATTGGTGGTAGGGTGGGGCGTTCGCCCGAGAGA
CCTACAGGGAAACTCTATTTCTTTCATGAAGGATTATCTAAATCAATGTTGCAATGTCGGAAAGAAATAAATGCAATGAA
TAAAAAAGGAGGGTTTGAAAATGAAGTGTCTACTATGTAA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(290-396)

Type III restriction enzyme, res subunit (ResIII)

(94-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

55.22

98.178

0.542
  comFA/cflA Streptococcus pneumoniae D39

55.22

98.178

0.542
  comFA/cflA Streptococcus pneumoniae R6

55.22

98.178

0.542
  comFA/cflA Streptococcus pneumoniae TIGR4

55.22

98.178

0.542
  comFA/cflA Streptococcus mitis NCTC 12261

54.884

97.95

0.538
  comFA/cflA Streptococcus mitis SK321

53.953

97.95

0.528
  comFA Lactococcus lactis subsp. cremoris KW2

45.952

95.672

0.44
  comFA Latilactobacillus sakei subsp. sakei 23K

37.011

99.089

0.367

Multiple sequence alignment