Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   H0504_RS07385 Genome accession   NZ_LR822011
Coordinates   1437261..1438778 (-) Length   505 a.a.
NCBI ID   WP_179971748.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_23     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1432261..1443778
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0504_RS07365 (STHERMO_1645) der 1433166..1434476 (-) 1311 WP_011680741.1 ribosome biogenesis GTPase Der -
  H0504_RS07370 (STHERMO_1646) dnaI 1434582..1435484 (-) 903 WP_002946786.1 primosomal protein DnaI -
  H0504_RS07375 (STHERMO_1647) - 1435488..1436663 (-) 1176 WP_002949643.1 DnaD domain protein -
  H0504_RS07380 (STHERMO_1648) nrdR 1436660..1437139 (-) 480 WP_002949642.1 transcriptional regulator NrdR -
  H0504_RS07385 (STHERMO_1649) covS 1437261..1438778 (-) 1518 WP_179971748.1 HAMP domain-containing histidine kinase Regulator
  H0504_RS07390 (STHERMO_1650) covR 1438775..1439464 (-) 690 WP_002949638.1 response regulator transcription factor Regulator
  H0504_RS07395 (STHERMO_1651) - 1439620..1440156 (-) 537 WP_041826965.1 DUF177 domain-containing protein -
  H0504_RS07400 (STHERMO_1652) rsmG 1440453..1441166 (+) 714 WP_002946490.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  H0504_RS07405 (STHERMO_1653) - 1441236..1442600 (+) 1365 WP_269473675.1 TrkH family potassium uptake protein -
  H0504_RS07410 (STHERMO_1654) - 1442640..1443311 (+) 672 WP_002946492.1 potassium channel family protein -
  H0504_RS09780 - 1443328..1443498 (-) 171 Protein_1428 ascorbate 6-phosphate lactonase -

Sequence

Protein


Download         Length: 505 a.a.        Molecular weight: 57521.92 Da        Isoelectric Point: 5.3824

>NTDB_id=1130682 H0504_RS07385 WP_179971748.1 1437261..1438778(-) (covS) [Streptococcus thermophilus isolate STH_CIRM_23]
MSKLFGKVTIRKKLTMTTAVVFFLVLSMFTLVVVFSANTLLLQRERQNVNNTISKVVTYIEKDWDSNEELSPEPLLAALY
SPKNIYPSIINGVLSEKRSLDGQVAVSNRLYSNQSVYVYDKKGTFIFTSEEDTDSPPGMSEVNKLKLVSYKGKRGFLLQV
PIYGKDKKTIVGYAQVFHDLEFYYALKERLIFLLIFLEVGMTVLVIAVTVVVLTSILRPMRQLHETMGIIIDSPSDLELR
SKIESHDEIGALALNFNCMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHEANRM
TIMINDMLDSIRVKGSFDNHRNDTCDLNSSIRTVIGNFRVLHDDYQFYLNDSEGSDRPAQIYSQHFEQVITILIDNAVKY
SPVNKKIQVTIKALEDEMLVQVQDNGEGISKEDIEHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCHIDVSSE
LGVGTRFDLYIPFAESETTTPQIEG

Nucleotide


Download         Length: 1518 bp        

>NTDB_id=1130682 H0504_RS07385 WP_179971748.1 1437261..1438778(-) (covS) [Streptococcus thermophilus isolate STH_CIRM_23]
ATGAGTAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTTTCTTGTATTGTC
GATGTTCACTCTGGTTGTTGTATTTTCAGCCAATACGCTTCTTTTGCAACGTGAACGTCAAAATGTAAATAATACAATCT
CAAAAGTTGTTACTTATATCGAAAAGGACTGGGACTCTAATGAAGAGTTGAGTCCAGAGCCGCTTTTAGCGGCCCTTTAT
TCACCGAAAAATATCTATCCATCAATCATTAATGGAGTGCTTTCTGAAAAGCGTTCCTTAGATGGTCAAGTTGCGGTTTC
TAATAGATTATATTCCAACCAGTCTGTCTATGTTTATGACAAAAAGGGAACTTTTATCTTTACTTCTGAGGAGGATACAG
ACTCACCTCCAGGCATGTCTGAGGTCAATAAACTGAAGTTGGTTTCCTATAAAGGTAAACGTGGTTTCTTACTACAAGTT
CCAATCTATGGCAAGGATAAGAAGACCATTGTTGGGTATGCTCAAGTTTTCCATGATTTGGAATTCTACTATGCGTTAAA
AGAGCGTTTAATTTTCCTATTGATATTCCTTGAAGTAGGAATGACGGTCTTAGTTATTGCAGTAACTGTAGTTGTCTTGA
CATCTATTCTTCGTCCGATGAGGCAGTTACACGAAACGATGGGTATTATTATCGATTCGCCAAGTGATTTGGAGCTTCGA
TCTAAGATTGAGAGTCATGATGAGATTGGTGCTTTGGCACTTAACTTTAACTGTATGATGGATAAAATTCAAGAAAATAA
TCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCACGAATTACGTACTCCCATTGCAGTTATTAAAGGACATATGGACC
TCTTGCAACGTTGGGGTAAAAATGATCCTGAAATCCTTGAAGAAAGTCTTGAAGCTGCAAGTCATGAAGCCAACCGTATG
ACGATTATGATTAACGATATGTTGGATTCTATTCGTGTTAAAGGGTCATTTGACAATCATAGAAATGATACATGTGATTT
GAATTCTTCAATCCGTACGGTTATTGGGAATTTTCGTGTCCTACATGACGACTACCAATTCTACCTCAATGATTCTGAGG
GTTCAGATCGTCCAGCACAGATTTACAGCCAGCACTTTGAACAGGTTATTACTATTTTGATTGATAATGCGGTCAAGTAT
TCGCCTGTTAATAAGAAAATCCAGGTTACTATCAAGGCTCTGGAAGATGAGATGCTGGTACAGGTACAGGATAATGGTGA
GGGTATCTCTAAAGAAGATATTGAACATATATTTGAACGCTTCTATCGTTCAGATAAGGCGCGTAATCGTACGACAACCC
AATCTGGTGTGGGTATTGGTTTATCAATCCTCTATCAAATTGTGGAAGCTTATCGATGCCATATCGATGTCAGTTCAGAA
CTTGGTGTGGGTACACGTTTTGACCTCTACATTCCTTTTGCAGAGTCAGAAACTACGACACCTCAAATTGAAGGTTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(270-329)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(384-494)

ArlS sensor domain (ArlS_N)

(39-187)

HAMP domain (HAMP)

(213-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

94.622

99.406

0.941

Multiple sequence alignment