Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   H0503_RS01850 Genome accession   NZ_LR822009
Coordinates   347070..348368 (+) Length   432 a.a.
NCBI ID   WP_179971469.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_19     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 342070..353368
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0503_RS01825 (STHERMO_0395) - 342922..343686 (+) 765 WP_002949740.1 ABC transporter ATP-binding protein -
  H0503_RS01830 (STHERMO_0396) - 343686..344396 (+) 711 WP_014607989.1 ABC transporter ATP-binding protein -
  H0503_RS01835 - 344532..345194 (+) 663 Protein_329 CBS and ACT domain-containing protein -
  H0503_RS01840 (STHERMO_0399) cysK 345361..346287 (-) 927 WP_014621180.1 cysteine synthase A -
  H0503_RS01845 (STHERMO_0400) - 346389..347015 (-) 627 WP_179971468.1 YigZ family protein -
  H0503_RS01850 (STHERMO_0401) comFA/cflA 347070..348368 (+) 1299 WP_179971469.1 DEAD/DEAH box helicase Machinery gene
  H0503_RS01855 (STHERMO_0402) - 348371..349033 (+) 663 WP_100262556.1 ComF family protein -
  H0503_RS01860 (STHERMO_0403) hpf 349112..349660 (+) 549 WP_095559242.1 ribosome hibernation-promoting factor, HPF/YfiA family -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49960.08 Da        Isoelectric Point: 9.9264

>NTDB_id=1130544 H0503_RS01850 WP_179971469.1 347070..348368(+) (comFA/cflA) [Streptococcus thermophilus isolate STH_CIRM_19]
MIPKEYYGRLFTKEQLPVDYLSEAVKLESMIKVDKKLRCKRCYSRIEEDWQLPNGQYYCRACIVFGRNQEGKELYYFPSE
KSEVDFPVLKWSGKLTPYQNEVSEKLLKTYKNQKHSLVHAVTGAGKTEIIYNIVAYVLENKNRVVIASPRVDVCRELFLR
MQKDFTCSISLLHADSEPYDGSPLVIATTHQLLKFYHSFDLIIVDEVDAFPFVGNVMLNHAVKQAKTETGRYIYLTATST
LALEEQVRLGAIEKHHLASRFHGNPLVLPRFFWQGRLQKSLTNEKLPRSLIHQIKKQRKSNFPLLIFFPNIALGEKFSIT
LKKYLPTENIAFVSSKSEERSTIVEKFRKKELSILVTTTILERGVTFPQVDVFVCMANHHLYTSSSLIQIGGRVGRSPER
PTGKLYFFHEGLSKSMLQCRKEINAMNKKRRV

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=1130544 H0503_RS01850 WP_179971469.1 347070..348368(+) (comFA/cflA) [Streptococcus thermophilus isolate STH_CIRM_19]
ATGATACCTAAAGAATATTATGGACGACTATTTACGAAAGAACAGTTACCAGTGGACTATCTCTCAGAGGCTGTAAAATT
AGAAAGTATGATAAAGGTTGATAAAAAACTTAGATGTAAAAGATGTTATAGTCGAATAGAGGAAGATTGGCAATTACCGA
ATGGTCAGTATTATTGTAGAGCGTGTATTGTCTTTGGTCGAAACCAAGAAGGAAAAGAACTCTATTACTTTCCCTCAGAA
AAATCAGAAGTAGATTTTCCTGTCTTGAAATGGTCAGGAAAACTGACTCCTTATCAAAATGAGGTCTCGGAAAAGCTTTT
AAAGACTTATAAAAATCAAAAACACAGTCTTGTTCATGCAGTGACTGGTGCTGGCAAGACAGAGATAATTTATAATATTG
TTGCCTATGTTCTTGAAAATAAAAATCGTGTCGTCATCGCAAGTCCCCGAGTTGATGTTTGTCGAGAATTGTTTCTACGC
ATGCAGAAAGATTTTACTTGTAGTATTTCTCTGCTTCATGCTGATAGTGAACCATATGATGGTAGTCCGCTCGTTATAGC
TACCACTCATCAATTACTAAAATTTTATCATAGCTTTGACTTGATTATTGTTGATGAAGTTGATGCCTTTCCATTTGTAG
GGAATGTCATGTTAAATCATGCTGTTAAACAGGCAAAGACGGAAACAGGCCGGTATATTTACTTAACAGCAACTTCTACA
TTAGCTTTAGAAGAGCAAGTGCGCCTTGGAGCTATAGAAAAGCATCACCTTGCTAGTCGTTTCCACGGAAATCCTTTAGT
CCTTCCTCGTTTCTTTTGGCAAGGAAGGTTACAAAAGTCGTTGACGAACGAGAAGCTTCCAAGGTCTCTAATTCACCAGA
TTAAGAAGCAGCGTAAATCAAATTTTCCTCTATTAATCTTTTTTCCCAATATAGCATTAGGTGAAAAGTTTAGTATTACC
CTAAAAAAATATCTCCCTACTGAAAACATAGCCTTTGTTTCATCAAAAAGCGAGGAGCGTTCAACCATCGTAGAGAAATT
CCGAAAAAAAGAATTGTCAATCTTAGTGACGACAACTATTCTCGAACGTGGTGTTACCTTTCCACAAGTAGATGTTTTTG
TTTGTATGGCAAATCATCACTTATATACTAGTTCGAGTCTTATTCAGATTGGTGGTAGGGTGGGGCGTTCGCCCGAGAGA
CCTACAGGGAAACTCTATTTCTTTCATGAAGGATTATCTAAATCAATGTTGCAATGTCGGAAAGAAATAAATGCAATGAA
TAAAAAAAGGAGGGTTTGA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(290-396)

Type III restriction enzyme, res subunit (ResIII)

(94-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae TIGR4

55.14

99.074

0.546
  comFA/cflA Streptococcus pneumoniae Rx1

55.14

99.074

0.546
  comFA/cflA Streptococcus pneumoniae D39

55.14

99.074

0.546
  comFA/cflA Streptococcus pneumoniae R6

55.14

99.074

0.546
  comFA/cflA Streptococcus mitis NCTC 12261

54.801

98.843

0.542
  comFA/cflA Streptococcus mitis SK321

53.864

98.843

0.532
  comFA Lactococcus lactis subsp. cremoris KW2

45.433

96.296

0.438
  comFA Latilactobacillus sakei subsp. sakei 23K

36.697

100

0.37

Multiple sequence alignment