Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   GPW69_RS08270 Genome accession   NZ_LR738724
Coordinates   1693648..1694337 (-) Length   229 a.a.
NCBI ID   WP_012027645.1    Uniprot ID   -
Organism   Streptococcus suis isolate 9401240     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1688648..1699337
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPW69_RS08245 - 1689118..1689831 (-) 714 WP_024399628.1 NADPH-dependent oxidoreductase -
  GPW69_RS08250 dnaI 1689828..1690727 (-) 900 WP_074391723.1 primosomal protein DnaI -
  GPW69_RS08255 - 1690727..1691878 (-) 1152 WP_074391722.1 replication initiation/membrane attachment protein -
  GPW69_RS08260 nrdR 1691865..1692356 (-) 492 WP_002938341.1 transcriptional regulator NrdR -
  GPW69_RS08265 - 1692428..1693558 (-) 1131 WP_024390116.1 AI-2E family transporter -
  GPW69_RS08270 covR 1693648..1694337 (-) 690 WP_012027645.1 DNA-binding response regulator Regulator
  GPW69_RS08275 gndA 1694419..1695846 (-) 1428 WP_002942698.1 NADP-dependent phosphogluconate dehydrogenase -
  GPW69_RS08280 - 1695943..1696482 (-) 540 WP_014736258.1 YceD family protein -
  GPW69_RS08285 trxB 1696492..1697409 (-) 918 WP_002942687.1 thioredoxin-disulfide reductase -
  GPW69_RS08290 - 1697423..1697647 (-) 225 WP_002936682.1 DUF4059 family protein -
  GPW69_RS08295 - 1697665..1699008 (-) 1344 WP_074391721.1 DEAD/DEAH box helicase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26255.14 Da        Isoelectric Point: 5.3968

>NTDB_id=1129612 GPW69_RS08270 WP_012027645.1 1693648..1694337(-) (covR) [Streptococcus suis isolate 9401240]
MAKKILIAGKERNLSHFVSMELQKKDYLVDYASTGKEAMSLAHETDFDLILMSFQLSDMSSKELATELLAIKPATVMIVV
VEPTEVSQYGEEVLSYAVSYVVKPFVISDLVEQISAIFRGRDFIDNNCKQVHMHAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEPVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDLPHQDSYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1129612 GPW69_RS08270 WP_012027645.1 1693648..1694337(-) (covR) [Streptococcus suis isolate 9401240]
ATGGCTAAGAAAATTTTGATTGCTGGTAAAGAACGCAATCTCTCGCATTTTGTTTCCATGGAATTGCAGAAAAAAGACTA
TCTTGTTGATTATGCATCGACAGGGAAAGAGGCTATGTCCTTGGCACATGAAACGGATTTTGACTTGATTCTGATGAGTT
TTCAGCTTTCAGACATGTCCAGCAAGGAATTGGCTACAGAACTGTTAGCGATAAAACCAGCCACGGTCATGATTGTGGTA
GTTGAGCCGACAGAAGTTAGTCAATATGGGGAAGAAGTCCTCTCTTATGCTGTTTCCTACGTAGTGAAGCCCTTTGTCAT
CAGTGATCTAGTGGAGCAAATCTCTGCGATTTTTCGTGGTCGTGATTTTATTGATAATAACTGTAAGCAGGTTCACATGC
ATGCGGCCTATCGTGATTTGAAGGTTGATTTTCAAAATCGAACAGTGACTCGAGGTGATGAATTGATTAATTTGACCCGC
CGAGAGTATGATCTGTTGGCGACCTTAATGAATAGCCCAGAGCCTGTTAGTCGAGAACAACTTCTTGAGCGTGTTTGGAA
ATATGAAGCGGCTTCTGAGACCAATGTCGTCGATGTATATATTCGCTATCTACGTGGTAAACTGGATTTGCCACATCAAG
ATTCATATATAAAAACAGTTCGTGGTGTCGGATATGCCATGCGCGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.619

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.949

100

0.432

Multiple sequence alignment