Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   GPW69_RS05350 Genome accession   NZ_LR738724
Coordinates   1076619..1077845 (-) Length   408 a.a.
NCBI ID   WP_002934974.1    Uniprot ID   G7SE29
Organism   Streptococcus suis isolate 9401240     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1071619..1082845
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPW69_RS05325 - 1071934..1073247 (-) 1314 WP_074391140.1 excalibur calcium-binding domain-containing protein -
  GPW69_RS05330 - 1073382..1073564 (+) 183 WP_002934978.1 4-oxalocrotonate tautomerase -
  GPW69_RS05335 lepA 1073614..1075446 (-) 1833 WP_029187235.1 translation elongation factor 4 -
  GPW69_RS05340 ndk 1075542..1075955 (-) 414 WP_074391141.1 nucleoside-diphosphate kinase -
  GPW69_RS05345 yihA 1075978..1076565 (-) 588 WP_014638915.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  GPW69_RS05350 clpX 1076619..1077845 (-) 1227 WP_002934974.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  GPW69_RS05360 - 1078043..1078555 (-) 513 WP_024405715.1 dihydrofolate reductase -
  GPW69_RS05365 - 1078892..1079731 (-) 840 WP_029177460.1 thymidylate synthase -
  GPW69_RS05370 - 1079783..1080085 (-) 303 WP_029752306.1 hypothetical protein -
  GPW69_RS05375 - 1080097..1080375 (-) 279 WP_002934968.1 hypothetical protein -
  GPW69_RS05380 - 1080501..1081460 (-) 960 WP_044674985.1 ROK family glucokinase -
  GPW69_RS05385 - 1081556..1081891 (-) 336 WP_044674984.1 hypothetical protein -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45318.84 Da        Isoelectric Point: 4.6382

>NTDB_id=1129597 GPW69_RS05350 WP_002934974.1 1076619..1077845(-) (clpX) [Streptococcus suis isolate 9401240]
MAVKHTHELIYCSFCGKNQEEVKKIIAGNNVFICNECVELAQEIIREELAEEVLTDLADTPKPQELLNILNNYVIGQDRA
KRALAVAVYNHYKRINFQDSRDENDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENIL
LKLLQAADFNIDRAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIHVDTKN
ILFIVGGAFDGIEEIVKQRLGEKIIGFGHNNRAIDEKESYMQHIIADDIQKFGIIPELIGRLPVFAALDQLTTEDLVRIL
TEPKNALVKQYQTLLSYDDVELDFDEDALLAIAEKAIERKTGARGLRSIIEETMLDVMFEVPGQDNVKRVRVTKAAVDGK
EKPLLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=1129597 GPW69_RS05350 WP_002934974.1 1076619..1077845(-) (clpX) [Streptococcus suis isolate 9401240]
ATGGCTGTTAAGCATACACATGAGCTAATCTATTGCTCATTTTGCGGAAAAAATCAAGAAGAAGTTAAAAAAATTATCGC
TGGAAACAATGTCTTCATTTGTAATGAATGCGTGGAACTAGCACAGGAAATCATTCGTGAGGAACTGGCAGAAGAAGTTT
TGACAGACTTAGCCGATACGCCAAAGCCACAAGAATTACTCAATATCCTGAACAACTATGTCATCGGACAGGATCGTGCA
AAACGTGCTTTAGCAGTAGCCGTTTACAACCACTACAAACGTATCAATTTCCAGGATAGCCGTGATGAGAACGATGTTGA
TTTGCAAAAGTCAAATATCCTTATGATTGGTCCGACTGGTTCAGGAAAAACCTTCCTAGCACAGACCTTGGCTAAAAGTT
TGAATGTCCCGTTTGCTATTGCTGATGCGACCGCTCTTACTGAGGCGGGTTATGTTGGTGAAGACGTAGAAAATATCCTC
CTCAAACTTTTGCAGGCTGCAGACTTTAACATCGACCGTGCAGAAAGAGGAATTATCTATGTGGATGAAATTGATAAAAT
TGCCAAAAAAGGTGAAAATGTGTCCATTACCCGCGATGTATCTGGTGAAGGTGTCCAGCAAGCTCTCCTAAAAATTATCG
AGGGAACTGTGGCCAGCGTACCACCACAAGGCGGACGCAAACATCCAAACCAAGAAATGATTCACGTGGACACCAAAAAT
ATCCTGTTTATCGTTGGCGGTGCATTTGATGGTATCGAAGAAATCGTCAAACAGCGTCTCGGTGAAAAAATCATCGGTTT
TGGTCATAATAATCGTGCTATTGATGAAAAAGAATCATACATGCAACATATCATTGCAGACGATATTCAAAAATTCGGTA
TCATTCCAGAGTTGATTGGTCGCTTGCCTGTATTCGCAGCTTTGGACCAATTGACAACAGAGGATTTGGTACGTATTTTG
ACGGAACCGAAGAATGCTCTTGTAAAACAATATCAGACACTCTTGTCTTATGATGACGTGGAGCTTGACTTTGATGAGGA
CGCCTTGTTAGCAATTGCAGAAAAAGCAATTGAACGTAAGACTGGCGCTCGTGGACTTCGTTCCATCATTGAAGAAACGA
TGTTGGATGTCATGTTTGAGGTGCCAGGCCAAGATAACGTTAAACGTGTTCGTGTAACAAAAGCAGCAGTAGACGGTAAG
GAAAAACCTTTACTAGAAACTGCTTAA

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G7SE29

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

83.13

100

0.833
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.209

98.529

0.574

Multiple sequence alignment