Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   GPW68_RS08895 Genome accession   NZ_LR738723
Coordinates   1767946..1768635 (-) Length   229 a.a.
NCBI ID   WP_012027645.1    Uniprot ID   -
Organism   Streptococcus suis isolate GD-0088     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1762946..1773635
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPW68_RS08870 - 1763416..1764129 (-) 714 WP_074389436.1 nitroreductase family protein -
  GPW68_RS08875 dnaI 1764126..1765025 (-) 900 WP_002938337.1 primosomal protein DnaI -
  GPW68_RS08880 - 1765025..1766176 (-) 1152 WP_074389435.1 replication initiation/membrane attachment protein -
  GPW68_RS08885 nrdR 1766163..1766654 (-) 492 WP_002938341.1 transcriptional regulator NrdR -
  GPW68_RS08890 - 1766726..1767856 (-) 1131 WP_012027644.1 AI-2E family transporter -
  GPW68_RS08895 covR 1767946..1768635 (-) 690 WP_012027645.1 DNA-binding response regulator Regulator
  GPW68_RS08900 gndA 1768717..1770144 (-) 1428 WP_002942698.1 NADP-dependent phosphogluconate dehydrogenase -
  GPW68_RS08905 - 1770241..1770780 (-) 540 WP_024385904.1 YceD family protein -
  GPW68_RS08910 trxB 1770790..1771707 (-) 918 WP_002942687.1 thioredoxin-disulfide reductase -
  GPW68_RS08915 - 1771721..1771945 (-) 225 WP_002936682.1 DUF4059 family protein -
  GPW68_RS08920 - 1771963..1773306 (-) 1344 WP_074389434.1 DEAD/DEAH box helicase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26255.14 Da        Isoelectric Point: 5.3968

>NTDB_id=1129562 GPW68_RS08895 WP_012027645.1 1767946..1768635(-) (covR) [Streptococcus suis isolate GD-0088]
MAKKILIAGKERNLSHFVSMELQKKDYLVDYASTGKEAMSLAHETDFDLILMSFQLSDMSSKELATELLAIKPATVMIVV
VEPTEVSQYGEEVLSYAVSYVVKPFVISDLVEQISAIFRGRDFIDNNCKQVHMHAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEPVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDLPHQDSYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1129562 GPW68_RS08895 WP_012027645.1 1767946..1768635(-) (covR) [Streptococcus suis isolate GD-0088]
ATGGCTAAGAAAATTTTGATTGCTGGTAAAGAACGCAATCTCTCGCATTTTGTTTCCATGGAATTGCAGAAAAAAGACTA
TCTTGTTGATTATGCATCGACAGGGAAAGAGGCTATGTCCTTGGCACATGAAACGGATTTTGACTTGATTCTGATGAGTT
TTCAGCTTTCAGACATGTCCAGCAAGGAATTGGCTACAGAACTATTAGCGATAAAACCAGCCACGGTCATGATTGTGGTA
GTTGAGCCGACTGAAGTTAGTCAATATGGGGAGGAAGTCCTCTCTTATGCTGTTTCCTACGTAGTGAAGCCCTTTGTCAT
CAGTGATTTAGTGGAGCAAATCTCTGCGATTTTTCGTGGTCGTGATTTTATTGACAATAACTGTAAACAGGTTCACATGC
ATGCGGCCTATCGTGATTTGAAGGTTGATTTTCAAAATCGAACAGTGACTCGAGGTGATGAATTGATTAATTTGACCCGC
CGAGAGTATGATCTGTTGGCGACCTTAATGAATAGCCCAGAGCCTGTTAGTCGAGAACAACTTCTTGAGCGTGTTTGGAA
ATATGAAGCGGCTTCTGAGACCAATGTCGTCGATGTATATATTCGCTATCTACGTGGTAAACTGGATTTGCCACATCAAG
ATTCATATATAAAAACAGTTCGTGGTGTCGGATATGCCATGCGCGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.619

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.949

100

0.432

Multiple sequence alignment