Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   GPW68_RS05920 Genome accession   NZ_LR738723
Coordinates   1166712..1167938 (-) Length   408 a.a.
NCBI ID   WP_002934974.1    Uniprot ID   G7SE29
Organism   Streptococcus suis isolate GD-0088     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1161712..1172938
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPW68_RS05885 - 1161739..1162320 (-) 582 WP_002934983.1 thymidine kinase -
  GPW68_RS05890 - 1162419..1162643 (-) 225 WP_024405711.1 hypothetical protein -
  GPW68_RS05895 - 1162766..1162948 (+) 183 WP_002934978.1 4-oxalocrotonate tautomerase -
  GPW68_RS11805 - 1163036..1163179 (-) 144 WP_323156734.1 IS3 family transposase -
  GPW68_RS05900 - 1163365..1163652 (-) 288 WP_074389419.1 hypothetical protein -
  GPW68_RS05905 lepA 1163706..1165538 (-) 1833 WP_024405713.1 translation elongation factor 4 -
  GPW68_RS05910 ndk 1165634..1166047 (-) 414 WP_024405714.1 nucleoside-diphosphate kinase -
  GPW68_RS05915 yihA 1166070..1166657 (-) 588 WP_014638915.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  GPW68_RS05920 clpX 1166712..1167938 (-) 1227 WP_002934974.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  GPW68_RS05930 - 1168136..1168648 (-) 513 WP_024411301.1 dihydrofolate reductase -
  GPW68_RS05935 - 1168986..1169825 (-) 840 WP_014637954.1 thymidylate synthase -
  GPW68_RS05940 - 1169878..1170180 (-) 303 WP_024383529.1 hypothetical protein -
  GPW68_RS05945 - 1170192..1170470 (-) 279 WP_012775087.1 hypothetical protein -
  GPW68_RS05950 - 1170597..1171556 (-) 960 WP_023370402.1 ROK family glucokinase -
  GPW68_RS05955 - 1171652..1171987 (-) 336 WP_002934966.1 hypothetical protein -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45318.84 Da        Isoelectric Point: 4.6382

>NTDB_id=1129556 GPW68_RS05920 WP_002934974.1 1166712..1167938(-) (clpX) [Streptococcus suis isolate GD-0088]
MAVKHTHELIYCSFCGKNQEEVKKIIAGNNVFICNECVELAQEIIREELAEEVLTDLADTPKPQELLNILNNYVIGQDRA
KRALAVAVYNHYKRINFQDSRDENDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENIL
LKLLQAADFNIDRAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIHVDTKN
ILFIVGGAFDGIEEIVKQRLGEKIIGFGHNNRAIDEKESYMQHIIADDIQKFGIIPELIGRLPVFAALDQLTTEDLVRIL
TEPKNALVKQYQTLLSYDDVELDFDEDALLAIAEKAIERKTGARGLRSIIEETMLDVMFEVPGQDNVKRVRVTKAAVDGK
EKPLLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=1129556 GPW68_RS05920 WP_002934974.1 1166712..1167938(-) (clpX) [Streptococcus suis isolate GD-0088]
ATGGCAGTTAAGCATACACATGAGCTAATCTATTGCTCATTTTGCGGAAAAAATCAAGAAGAAGTTAAAAAAATTATCGC
AGGGAACAATGTCTTCATTTGTAATGAGTGCGTGGAACTAGCACAGGAAATCATTCGTGAGGAACTGGCAGAAGAAGTTT
TGACAGACTTGGCCGATACACCAAAGCCACAAGAATTACTCAATATCCTGAACAACTACGTCATCGGACAGGATCGTGCA
AAACGTGCTTTAGCAGTAGCCGTTTACAACCACTATAAACGTATCAATTTCCAAGATAGCCGTGATGAGAACGATGTTGA
TTTGCAAAAATCAAATATCCTTATGATTGGCCCGACTGGTTCAGGAAAAACCTTCCTAGCTCAGACCTTGGCTAAAAGTT
TGAATGTCCCTTTTGCTATTGCCGATGCGACCGCTCTTACTGAGGCGGGTTATGTTGGTGAAGACGTAGAAAATATCCTC
CTCAAACTTTTGCAGGCTGCAGACTTTAACATCGACCGTGCAGAAAGAGGAATTATCTATGTGGATGAAATTGATAAAAT
TGCCAAAAAAGGTGAAAATGTGTCCATTACCCGCGATGTATCTGGTGAAGGTGTCCAGCAAGCTCTCCTAAAAATTATCG
AGGGAACTGTGGCCAGCGTACCACCACAAGGTGGACGCAAACATCCAAACCAAGAAATGATTCACGTGGACACCAAAAAT
ATCCTGTTTATCGTTGGCGGTGCATTTGATGGTATCGAAGAAATCGTCAAGCAGCGTCTCGGTGAAAAAATCATCGGTTT
TGGTCATAATAATCGTGCTATTGATGAAAAAGAATCATACATGCAACATATCATTGCAGACGATATTCAAAAATTCGGTA
TCATTCCAGAGTTGATTGGTCGCTTGCCTGTATTCGCAGCTTTGGACCAATTGACAACAGAGGATTTGGTACGCATTTTG
ACGGAACCGAAGAATGCTCTTGTAAAACAATACCAGACACTCTTGTCTTATGATGACGTGGAGCTTGACTTTGATGAGGA
CGCCTTGTTAGCAATTGCAGAAAAAGCAATTGAACGTAAAACTGGTGCTCGTGGACTTCGCTCCATCATTGAAGAAACGA
TGTTGGATGTCATGTTTGAGGTGCCAGGTCAAGATAACGTTAAACGCGTTCGTGTAACCAAAGCAGCAGTAGACGGTAAG
GAAAAGCCTTTACTAGAAACTGCATAA

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G7SE29

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

83.13

100

0.833
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.209

98.529

0.574

Multiple sequence alignment