Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   STREPSUIS_RS01935 Genome accession   NZ_LR738722
Coordinates   369905..370594 (+) Length   229 a.a.
NCBI ID   WP_012027645.1    Uniprot ID   -
Organism   Streptococcus suis isolate 861160     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 364905..375594
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STREPSUIS_RS01910 - 365234..366577 (+) 1344 WP_074390039.1 DEAD/DEAH box helicase -
  STREPSUIS_RS01915 - 366595..366819 (+) 225 WP_002936682.1 DUF4059 family protein -
  STREPSUIS_RS01920 trxB 366833..367750 (+) 918 WP_002942687.1 thioredoxin-disulfide reductase -
  STREPSUIS_RS01925 - 367760..368299 (+) 540 WP_024385904.1 YceD family protein -
  STREPSUIS_RS01930 gndA 368396..369823 (+) 1428 WP_002942698.1 NADP-dependent phosphogluconate dehydrogenase -
  STREPSUIS_RS01935 covR 369905..370594 (+) 690 WP_012027645.1 DNA-binding response regulator Regulator
  STREPSUIS_RS01940 - 370684..371814 (+) 1131 WP_014636113.1 AI-2E family transporter -
  STREPSUIS_RS01945 nrdR 371886..372377 (+) 492 WP_002938341.1 transcriptional regulator NrdR -
  STREPSUIS_RS01950 - 372364..373515 (+) 1152 WP_029174426.1 replication initiation/membrane attachment protein -
  STREPSUIS_RS01955 dnaI 373515..374414 (+) 900 WP_029174425.1 primosomal protein DnaI -
  STREPSUIS_RS01960 - 374411..375124 (+) 714 WP_053861635.1 NADPH-dependent oxidoreductase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26255.14 Da        Isoelectric Point: 5.3968

>NTDB_id=1129485 STREPSUIS_RS01935 WP_012027645.1 369905..370594(+) (covR) [Streptococcus suis isolate 861160]
MAKKILIAGKERNLSHFVSMELQKKDYLVDYASTGKEAMSLAHETDFDLILMSFQLSDMSSKELATELLAIKPATVMIVV
VEPTEVSQYGEEVLSYAVSYVVKPFVISDLVEQISAIFRGRDFIDNNCKQVHMHAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEPVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDLPHQDSYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1129485 STREPSUIS_RS01935 WP_012027645.1 369905..370594(+) (covR) [Streptococcus suis isolate 861160]
ATGGCTAAGAAAATTTTGATTGCTGGTAAAGAACGCAATCTCTCGCATTTTGTTTCCATGGAATTGCAGAAAAAAGACTA
TCTTGTTGATTATGCATCGACAGGGAAAGAGGCTATGTCCTTGGCACATGAAACGGATTTTGACTTGATTCTGATGAGTT
TTCAGCTTTCAGACATGTCCAGCAAGGAATTGGCTACAGAACTATTAGCGATAAAACCAGCCACGGTCATGATTGTGGTA
GTTGAGCCGACTGAAGTTAGTCAATATGGGGAGGAAGTCCTCTCTTATGCTGTTTCCTACGTAGTGAAGCCCTTTGTCAT
CAGTGATTTAGTGGAGCAAATCTCTGCGATTTTTCGTGGTCGTGATTTTATTGACAATAACTGTAAACAGGTTCACATGC
ATGCGGCCTATCGTGATTTGAAGGTTGATTTTCAAAATCGAACAGTGACTCGAGGTGATGAATTGATTAATTTGACCCGC
CGAGAGTATGATCTGTTGGCGACCTTAATGAATAGCCCAGAGCCTGTTAGTCGAGAACAACTTCTTGAGCGTGTTTGGAA
ATATGAAGCGGCTTCTGAGACCAATGTCGTCGATGTATATATTCGCTATCTACGTGGTAAACTGGATTTGCCACATCAAG
ATTCATATATAAAAACAGTTCGTGGTGTCGGATATGCCATGCGCGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.619

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.949

100

0.432

Multiple sequence alignment