Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   GPW48_RS05220 Genome accession   NZ_LR738720
Coordinates   1006964..1008190 (+) Length   408 a.a.
NCBI ID   WP_002934974.1    Uniprot ID   G7SE29
Organism   Streptococcus suis isolate GD-0001     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1001964..1013190
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPW48_RS05185 - 1002915..1003250 (+) 336 WP_002934966.1 hypothetical protein -
  GPW48_RS05190 - 1003346..1004305 (+) 960 WP_023370402.1 ROK family glucokinase -
  GPW48_RS05195 - 1004432..1004710 (+) 279 WP_012775087.1 hypothetical protein -
  GPW48_RS05200 - 1004722..1005024 (+) 303 WP_024383529.1 hypothetical protein -
  GPW48_RS05205 - 1005077..1005916 (+) 840 WP_014637954.1 thymidylate synthase -
  GPW48_RS05210 - 1006254..1006766 (+) 513 WP_024411301.1 dihydrofolate reductase -
  GPW48_RS05220 clpX 1006964..1008190 (+) 1227 WP_002934974.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  GPW48_RS05225 yihA 1008245..1008832 (+) 588 WP_014638915.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  GPW48_RS05230 ndk 1008855..1009268 (+) 414 WP_024405714.1 nucleoside-diphosphate kinase -
  GPW48_RS05235 lepA 1009364..1011196 (+) 1833 WP_024405713.1 translation elongation factor 4 -
  GPW48_RS05240 - 1011250..1011537 (+) 288 WP_024405712.1 hypothetical protein -
  GPW48_RS10910 - 1011723..1011866 (+) 144 WP_323156734.1 IS3 family transposase -
  GPW48_RS05245 - 1011954..1012136 (-) 183 WP_002934978.1 4-oxalocrotonate tautomerase -
  GPW48_RS05250 - 1012259..1012483 (+) 225 WP_024405711.1 hypothetical protein -
  GPW48_RS05255 - 1012582..1013163 (+) 582 WP_002934983.1 thymidine kinase -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45318.84 Da        Isoelectric Point: 4.6382

>NTDB_id=1129392 GPW48_RS05220 WP_002934974.1 1006964..1008190(+) (clpX) [Streptococcus suis isolate GD-0001]
MAVKHTHELIYCSFCGKNQEEVKKIIAGNNVFICNECVELAQEIIREELAEEVLTDLADTPKPQELLNILNNYVIGQDRA
KRALAVAVYNHYKRINFQDSRDENDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENIL
LKLLQAADFNIDRAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIHVDTKN
ILFIVGGAFDGIEEIVKQRLGEKIIGFGHNNRAIDEKESYMQHIIADDIQKFGIIPELIGRLPVFAALDQLTTEDLVRIL
TEPKNALVKQYQTLLSYDDVELDFDEDALLAIAEKAIERKTGARGLRSIIEETMLDVMFEVPGQDNVKRVRVTKAAVDGK
EKPLLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=1129392 GPW48_RS05220 WP_002934974.1 1006964..1008190(+) (clpX) [Streptococcus suis isolate GD-0001]
ATGGCAGTTAAGCATACACATGAGCTAATCTATTGCTCATTTTGCGGAAAAAATCAAGAAGAAGTTAAAAAAATTATCGC
AGGGAACAATGTCTTCATTTGTAATGAGTGCGTGGAACTAGCACAGGAAATCATTCGTGAGGAACTGGCAGAAGAAGTTT
TGACAGACTTGGCCGATACACCAAAGCCACAAGAATTACTCAATATCCTGAACAACTACGTCATCGGACAGGATCGTGCA
AAACGTGCTTTAGCAGTAGCCGTTTACAACCACTATAAACGTATCAATTTCCAAGATAGCCGTGATGAGAACGATGTTGA
TTTGCAAAAATCAAATATCCTTATGATTGGCCCGACTGGTTCAGGAAAAACCTTCCTAGCTCAGACCTTGGCTAAAAGTT
TGAATGTCCCTTTTGCTATTGCCGATGCGACCGCTCTTACTGAGGCGGGTTATGTTGGTGAAGACGTAGAAAATATCCTC
CTCAAACTTTTGCAGGCTGCAGACTTTAACATCGACCGTGCAGAAAGAGGAATTATCTATGTGGATGAAATTGATAAAAT
TGCCAAAAAAGGTGAAAATGTGTCCATTACCCGCGATGTATCTGGTGAAGGTGTCCAGCAAGCTCTCCTAAAAATTATCG
AGGGAACTGTGGCCAGCGTACCACCACAAGGTGGACGCAAACATCCAAACCAAGAAATGATTCACGTGGACACCAAAAAT
ATCCTGTTTATCGTTGGCGGTGCATTTGATGGTATCGAAGAAATCGTCAAGCAGCGTCTCGGTGAAAAAATCATCGGTTT
TGGTCATAATAATCGTGCTATTGATGAAAAAGAATCATACATGCAACATATCATTGCAGACGATATTCAAAAATTCGGTA
TCATTCCAGAGTTGATTGGTCGCTTGCCTGTATTCGCAGCTTTGGACCAATTGACAACAGAGGATTTGGTACGCATTTTG
ACGGAACCGAAGAATGCTCTTGTAAAACAATACCAGACACTCTTGTCTTATGATGACGTGGAGCTTGACTTTGATGAGGA
CGCCTTGTTAGCAATTGCAGAAAAAGCAATTGAACGTAAAACTGGTGCTCGTGGACTTCGCTCCATCATTGAAGAAACGA
TGTTGGATGTCATGTTTGAGGTGCCAGGTCAAGATAACGTTAAACGCGTTCGTGTAACCAAAGCAGCAGTAGACGGTAAG
GAAAAGCCTTTACTAGAAACTGCATAA

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G7SE29

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

83.13

100

0.833
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.209

98.529

0.574

Multiple sequence alignment